Baş Dönmesi Olan Hastalarda Periferik ve Santral Vertigonun Ayırt Edilmesinde Nötrofil/Lenfosit Oranının Tanısal Değeri

Öz

Amaç: Nötrofil/lenfosit oranı (NLR), sistemik inflamatuar yanıt ve hücresel bağışıklık yanıtı hakkında fikir veren düşük maliyetli bir parametredir. Bu çalışmanın amacı, NLR'nin periferik ve merkezi vertigo arasındaki farkı ayırt etmedeki değerini araştırmaktır. Materyal ve Metot: Ocak 2017 ile Aralık 2018 tarihleri arasında acil klinikte akut vertigo ile başvuran hastalar çalışmaya dahil edildi. Hastaları periferik ve merkezi vertigo gruplarına ayırmak için hemogram, beyin bilgisayarlı tomografi ve difüzyon manyetik rezonans görüntüleme verileri incelendi. Laboratuvar parametreleri bu gruplar arasında karşılaştırıldı. Bulgular: Nötrofil, lenfosit ve C-reaktif protein düzeyleri, periferik vertigo hastalarına kıyasla merkezi vertigo hastalarında daha yüksek bulundu (sırasıyla p=0,03, p=0,003, p=0,022). Ayrıca, NLR değeri merkezi vertigo vakalarında (ortalama: 3,99), periferik vertigo vakalarına kıyasla (ortalama: 2,32) anlamlı derecede yüksekti (p <0,001). Sonuç: NLR, vertigo semptomlarıyla acil servise başvuran hastalarda periferik ve merkezi vertigo arasındaki farkı ayırt etmede değerli bir belirleyicidir. Yüksek NLR değerleri merkezi vertigoyu düşündürmektedir.

Anahtar Kelimeler

• Acil servis
• ayırıcı tanı
• baş dönmesi
• nötrofil/lenfosit oranı
• vertigo

Diagnostic Value of Neutrophil/Lymphocyte Ratio in Distinguishing Peripheral and Central Vertigo in Patients with Dizziness

Öz

Objective: Neutrophil/lymphocyte ratio (NLR) is an inexpensive parameter that gives an idea about systemic inflammatory response and cellular immune response. This study aims to investigate the value of NLR in distinguishing peripheral and central vertigo. Materials and Methods: Patients presenting with acute vertigo at the emergency clinic were included between January 2017 and December 2018. Hemogram, brain computerized tomography, and diffusion magnetic resonance imaging data were reviewed to categorize patients into peripheral and central vertigo groups. Laboratory parameters were compared between these groups. Results: Neutrophil, lymphocyte, and C-reactive protein levels were higher in patients with central vertigo than those with peripheral vertigo (p=0.003, p=0.003, p=0.022, respectively). Moreover, the NLR value was significantly elevated in central vertigo cases (median: 3.99) in contrast to peripheral vertigo cases (median: 2.32) (p <0.001). Conclusions: The NLR is a valuable marker for distinguishing peripheral and central vertigo in emergency department patients with dizziness. Higher NLR values suggest central vertigo.

Anahtar Kelimeler

• Emergency department
• differential diagnosis
• dizziness
• neutrophil/lymphocyte ratio
• vertigo

Kaynakça

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