Araştırma Makalesi
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Vascular Zone Matters: Clinical Outcomes of Arthroscopic Meniscal Repair in Red–Red, Red–White, and White–White Tears

Yıl 2026, Cilt: 11 Sayı: 1, 24 - 31, 15.03.2026
https://doi.org/10.26453/otjhs.1813497
https://izlik.org/JA93AY29EP

Öz

Objective: Meniscal repair is superior to meniscectomy in preserving knee biomechanics and preventing degenerative progression. However, the healing potential may differ depending on the vascular zone. This study aimed to compare the clinical and functional outcomes of meniscal tears located in distinct vascular regions. Materials and Methods: A retrospective review was conducted on 118 patients who underwent arthroscopic meniscal repair between 2015 and 2025, with a minimum 12-month follow-up. Tears were categorized as red–red (RR, n=42), red–white (RW, n=53), or white–white (WW, n=23). Outcomes were assessed using IKDC, Lysholm, and VAS scores. Return-to-sport time, patient satisfaction, and complication rates were also analyzed. Group comparisons and multivariate logistic regression were performed to determine independent predictors of failure. Results: At the 12-month follow-up, functional scores were significantly higher in the RR group (IKDC 89.3; Lysholm 91.7) and VAS scores were lower (1.8) than in other groups (p<0.001). The mean return-to-sport time was shorter in RR tears (5.8 months) than in RW (6.4) and WW (8.2) groups (p<0.001). Satisfaction was highest in RR (90.5%) and lowest in WW (60.9%) tears (p=0.004). Complications were least frequent in RR (14.3%) and most common in WW (39.1%; p=0.03). WW localization independently predicted repair failure (OR=4.98; 95% CI: 1.88–13.18; p=0.001). Conclusion: Meniscal repair outcomes vary according to vascular zone. RR-zone tears achieve better function, faster recovery, and fewer complications, whereas WW-zone tears have a higher risk of reoperation. Vascular zone evaluation should guide surgical decision-making.

Etik Beyan

This study was approved by the Non-Interventional Clinical Research Ethics Committee of Düzce University (Date: 22/09/2025; Decision No: 2025/256) and conducted in accordance with the principles of the Declaration of Helsinki (2013 revision). Owing to the retrospective design, no additional interventions were performed, and the requirement for written informed consent was waived. All patient data were anonymised prior to analysis to ensure confidentiality.

Kaynakça

  • 1. Patil SS, Shekhar A, Tapasvi SR. Meniscal Preservation is Important for the Knee Joint. Indian journal of orthopaedics. Sep-Oct 2017;51(5):576-587. doi:10.4103/ortho.IJOrtho_247_17
  • 2. Hantouly AT, Aminake G, Khan AS, et al. Meniscus root tears: state of the art. International orthopaedics. 2024;48(4):955-964.
  • 3. Gajjar SM, Solanki KP, Shanmugasundaram S, Kambhampati SBS. Meniscal Extrusion: A Narrative Review. Orthopaedic journal of sports medicine. Nov 2021;9(11):23259671211043797. doi:10.1177/23259671211043797
  • 4. Kuczyński N, Boś J, Białoskórska K, et al. The Meniscus: Basic Science and Therapeutic Approaches. Journal of Clinical Medicine. 2025;14(6):2020.
  • 5. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomaterials. Oct 2011;32(30):7411-31. doi:10.1016/j.biomaterials.2011.06.037
  • 6. Khan M, Evaniew N, Bedi A, Ayeni OR, Bhandari M. Arthroscopic surgery for degenerative tears of the meniscus: a systematic review and meta-analysis. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. Oct 7 2014;186(14):1057-64. doi:10.1503/cmaj.140433
  • 7. Jahani A, Ebrahimzadeh MH. Clinical outcomes of artificial meniscus scaffolds for partial meniscus injury: a systematic review and meta-analysis. Sep 30 2025;37(1):41. doi:10.1186/s43019-025-00293-2
  • 8. Orellana F, Zaffagnini S, Hlushchuk R, Khoma OZ, Halm S, Parrilli A. Vascularization Characteristics of the Different Meniscal Layers: Three-Dimensional Assessment With Micro-CT. Jun 2025;13(6):23259671251341472. doi:10.1177/23259671251341472
  • 9. Mameri ES, Dasari SP, Fortier LM, et al. Review of Meniscus Anatomy and Biomechanics. Current reviews in musculoskeletal medicine. Oct 2022;15(5):323-335. doi:10.1007/s12178-022-09768-1
  • 10. Gerritsen LM, van der Lelij TJN, van Schie P, et al. Higher healing rate after meniscal repair with concomitant ACL reconstruction for tears located in vascular zone 1 compared to zone 2: a systematic review and meta-analysis. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. Jun 2022;30(6):1976-1989. doi:10.1007/s00167-022-06862-2
  • 11. Song X, Chen D, Qi X, Jiang Q, Xia C. Which factors are associated with the prevalence of meniscal repair? BMC musculoskeletal disorders. Mar 22 2021;22(1):295. doi:10.1186/s12891-021-04107-w
  • 12. Salem HS, Huston LJ, Zajichek A, et al. Anterior Cruciate Ligament Reconstruction With Concomitant Meniscal Repair: Is Graft Choice Predictive of Meniscal Repair Success? Orthopaedic journal of sports medicine. Sep 2021;9(9):23259671211033584. doi:10.1177/23259671211033584
  • 13. Bingol I, Kamaci S, Kaya I, et al. Low meniscus reoperation rates following meniscus repair during anterior cruciate ligament reconstruction in Turkey: an in-depth national analysis of 8-years. BMC musculoskeletal disorders. 2024;25(1):554.
  • 14. Ferrari MB, Murphy CP, Gomes JLE. Meniscus Repair in Children and Adolescents: A Systematic Review of Treatment Approaches, Meniscal Healing, and Outcomes. The journal of knee surgery. Jun 2019;32(6):490-498. doi:10.1055/s-0038-1653943
  • 15. Hohmann E. Editorial Commentary: Discovery: Progenitor Cells and Endothelial Cells Are Found in the White-White Zone of the Meniscus, But This Does Not Mean That These Tears Heal or Should Be Repaired. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Jan 2021;37(1):266-267. doi:10.1016/j.arthro.2020.11.007
  • 16. Bahcecioglu G, Bilgen B, Hasirci N, Hasirci V. Anatomical meniscus construct with zone specific biochemical composition and structural organization. Biomaterials. Oct 2019;218:119361. doi:10.1016/j.biomaterials.2019.119361
  • 17. Cinque ME, DePhillipo NN, Moatshe G, et al. Clinical Outcomes of Inside-Out Meniscal Repair According to Anatomic Zone of the Meniscal Tear. Orthopaedic journal of sports medicine. Jul 2019;7(7):2325967119860806. doi:10.1177/2325967119860806
  • 18. Angele P, Docheva D, Pattappa G, Zellner J. Cell-based treatment options facilitate regeneration of cartilage, ligaments and meniscus in demanding conditions of the knee by a whole joint approach. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. Apr 2022;30(4):1138-1150. doi:10.1007/s00167-021-06497-9
  • 19. Kwon H, Brown WE, Lee CA, et al. Surgical and tissue engineering strategies for articular cartilage and meniscus repair. Nature reviews Rheumatology. Sep 2019;15(9):550-570. doi:10.1038/s41584-019-0255-1
  • 20. Rhim HC, Jeon OH, Han SB, Bae JH, Suh DW, Jang KM. Mesenchymal stem cells for enhancing biological healing after meniscal injuries. World journal of stem cells. Aug 26 2021;13(8):1005-1029. doi:10.4252/wjsc.v13.i8.1005
  • 21. Barber-Westin SD, Noyes FR. Clinical healing rates of meniscus repairs of tears in the central-third (red-white) zone. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Jan 2014;30(1):134-46. doi:10.1016/j.arthro.2013.10.003
  • 22. Mordecai SC, Al-Hadithy N, Ware HE, Gupte CM. Treatment of meniscal tears: An evidence based approach. World journal of orthopedics. Jul 18 2014;5(3):233-41. doi:10.5312/wjo.v5.i3.233
  • 23. Bansal S, Floyd ER. Meniscal repair: The current state and recent advances in augmentation. Jul 2021;39(7):1368-1382. doi:10.1002/jor.25021
  • 24. Lin KM, Gadinsky NE, Klinger CE, et al. Increased Vascularity in the Neonatal versus Adult Meniscus: Evaluation with Magnetic Resonance Imaging. Cartilage. Dec 2021;13(2_suppl):1562s-1569s. doi:10.1177/1947603520923143
  • 25. Wu M, Su Q, Zhao Q, Liu S. Evidence-based weight-bearing protocols after meniscal repair: balancing functional recovery and healing safety across injury types. Journal of orthopaedic surgery and research. Jun 19 2025;20(1):604. doi:10.1186/s13018-025-05988-6
  • 26. Berzolla E, Sundaram V, Strauss E. A Review of Revision Meniscal Repair: Clinical Considerations and Outcomes. Current reviews in musculoskeletal medicine. Sep 2025;18(9):344-352. doi:10.1007/s12178-025-09968-5
  • 27. Kamaci S, Pace JL. Redefining Failure: Criteria for Unsuccessful Outcomes in Meniscus Repair. Current reviews in musculoskeletal medicine. Sep 2025;18(9):353-360. doi:10.1007/s12178-025-09971-w
  • 28. Gallacher P, Gilbert R, Kanes G, Roberts S, Rees D. White on white meniscal tears to fix or not to fix? The Knee. 2010;17(4):270-273.
  • 29. Oeding JF, Berlinberg EJ, Lu Y, et al. Platelet-Rich Plasma and Marrow Venting May Serve as Cost-Effective Augmentation Techniques for Isolated Meniscal Repair: A Decision-Analytical Markov Model-Based Analysis. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Sep 2023;39(9):2058-2068. doi:10.1016/j.arthro.2023.02.018
  • 30. Paxton ES, Stock MV, Brophy RH. Meniscal repair versus partial meniscectomy: a systematic review comparing reoperation rates and clinical outcomes. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Sep 2011;27(9):1275-88. doi:10.1016/j.arthro.2011.03.088

Vasküler Zon Önemlidir: Kırmızı–Kırmızı, Kırmızı–Beyaz ve Beyaz–Beyaz Yırtıklarda Artroskopik Menisküs Onarımının Klinik Sonuçları

Yıl 2026, Cilt: 11 Sayı: 1, 24 - 31, 15.03.2026
https://doi.org/10.26453/otjhs.1813497
https://izlik.org/JA93AY29EP

Öz

Giriş: Menisküs onarımı, diz biyomekaniğinin korunması ve dejeneratif süreçlerin önlenmesinin sağlanması açısından menisektomiye göre daha üstün kabul edilmektedir. Ancak onarım başarısı, menisküsün bulunduğu vasküler zonun kanlanma düzeyine bağlı olarak değişiklik gösterebilmektedir. Bu çalışma, farklı vasküler bölgelerdeki menisküs yırtıklarında klinik ve fonksiyonel sonuçları karşılaştırmayı amaçlamıştır. Materyal ve Metot: 2015–2025 yılları arasında artroskopik menisküs onarımı uygulanan ve en az 12 ay takip edilen 118 hasta retrospektif olarak incelendi. Yırtıklar kırmızı–kırmızı (RR, n=42), kırmızı–beyaz (RW, n=53) ve beyaz–beyaz (WW, n=23) zon olarak sınıflandırıldı. Fonksiyonel sonuçlar IKDC, Lysholm ve VAS skorlarıyla değerlendirildi; spora dönüş süresi, hasta memnuniyeti ve komplikasyon oranları kaydedildi. Gruplar arası farklar uygun istatistiksel testlerle analiz edildi ve onarım başarısızlığını öngören bağımsız değişkenler çok değişkenli lojistik regresyon analizinde belirlendi. Bulgular: On ikinci ayda RR grubunda fonksiyonel skorlar anlamlı olarak daha yüksekti (IKDC: 89,3; Lysholm: 91,7) ve ağrı skorları daha düşüktü (VAS: 1,8) (p<0,001). Spora dönüş süresi RR grubunda (5,8 ay), RW (6,4 ay) ve WW (8,2 ay) gruplarına kıyasla daha kısaydı (p<0,001). Hasta memnuniyeti RR grubunda en yüksek (%90,5), WW grubunda en düşüktü (%60,9) (p=0,004). Komplikasyon oranı RR grubunda %14,3, WW grubunda %39,1 olarak saptandı (p=0,03). Lojistik regresyon analizinde WW lokalizasyonu onarım başarısızlığının bağımsız bir öngördürücüsü olarak belirlendi (OR=4,98; %95 GA: 1,88–13,18; p=0,001). Sonuç: Menisküs onarımının başarısı, yırtığın bulunduğu vasküler zonla yakından ilişkilidir. RR zonundaki yırtıklar daha iyi fonksiyonel iyileşme, daha hızlı spora dönüş ve daha düşük komplikasyon oranları göstermektedir. Buna karşılık WW zonundaki yırtıklar daha yüksek başarısızlık riski taşımaktadır.

Etik Beyan

Bu çalışma, Düzce Üniversitesi Girişimsel Olmayan Klinik Araştırmalar Etik Kurulu tarafından onaylanmıştır (Tarih: 22/09/2025; Karar No: 2025/256) ve Helsinki Bildirgesi'nin (2013 revizyonu) ilkelerine uygun olarak yürütülmüştür. Retrospektif tasarım nedeniyle ek müdahaleler yapılmamış ve yazılı bilgilendirilmiş onam şartı kaldırılmıştır. Gizliliğin sağlanması için tüm hasta verileri analizden önce anonimleştirilmiştir.

Kaynakça

  • 1. Patil SS, Shekhar A, Tapasvi SR. Meniscal Preservation is Important for the Knee Joint. Indian journal of orthopaedics. Sep-Oct 2017;51(5):576-587. doi:10.4103/ortho.IJOrtho_247_17
  • 2. Hantouly AT, Aminake G, Khan AS, et al. Meniscus root tears: state of the art. International orthopaedics. 2024;48(4):955-964.
  • 3. Gajjar SM, Solanki KP, Shanmugasundaram S, Kambhampati SBS. Meniscal Extrusion: A Narrative Review. Orthopaedic journal of sports medicine. Nov 2021;9(11):23259671211043797. doi:10.1177/23259671211043797
  • 4. Kuczyński N, Boś J, Białoskórska K, et al. The Meniscus: Basic Science and Therapeutic Approaches. Journal of Clinical Medicine. 2025;14(6):2020.
  • 5. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomaterials. Oct 2011;32(30):7411-31. doi:10.1016/j.biomaterials.2011.06.037
  • 6. Khan M, Evaniew N, Bedi A, Ayeni OR, Bhandari M. Arthroscopic surgery for degenerative tears of the meniscus: a systematic review and meta-analysis. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. Oct 7 2014;186(14):1057-64. doi:10.1503/cmaj.140433
  • 7. Jahani A, Ebrahimzadeh MH. Clinical outcomes of artificial meniscus scaffolds for partial meniscus injury: a systematic review and meta-analysis. Sep 30 2025;37(1):41. doi:10.1186/s43019-025-00293-2
  • 8. Orellana F, Zaffagnini S, Hlushchuk R, Khoma OZ, Halm S, Parrilli A. Vascularization Characteristics of the Different Meniscal Layers: Three-Dimensional Assessment With Micro-CT. Jun 2025;13(6):23259671251341472. doi:10.1177/23259671251341472
  • 9. Mameri ES, Dasari SP, Fortier LM, et al. Review of Meniscus Anatomy and Biomechanics. Current reviews in musculoskeletal medicine. Oct 2022;15(5):323-335. doi:10.1007/s12178-022-09768-1
  • 10. Gerritsen LM, van der Lelij TJN, van Schie P, et al. Higher healing rate after meniscal repair with concomitant ACL reconstruction for tears located in vascular zone 1 compared to zone 2: a systematic review and meta-analysis. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. Jun 2022;30(6):1976-1989. doi:10.1007/s00167-022-06862-2
  • 11. Song X, Chen D, Qi X, Jiang Q, Xia C. Which factors are associated with the prevalence of meniscal repair? BMC musculoskeletal disorders. Mar 22 2021;22(1):295. doi:10.1186/s12891-021-04107-w
  • 12. Salem HS, Huston LJ, Zajichek A, et al. Anterior Cruciate Ligament Reconstruction With Concomitant Meniscal Repair: Is Graft Choice Predictive of Meniscal Repair Success? Orthopaedic journal of sports medicine. Sep 2021;9(9):23259671211033584. doi:10.1177/23259671211033584
  • 13. Bingol I, Kamaci S, Kaya I, et al. Low meniscus reoperation rates following meniscus repair during anterior cruciate ligament reconstruction in Turkey: an in-depth national analysis of 8-years. BMC musculoskeletal disorders. 2024;25(1):554.
  • 14. Ferrari MB, Murphy CP, Gomes JLE. Meniscus Repair in Children and Adolescents: A Systematic Review of Treatment Approaches, Meniscal Healing, and Outcomes. The journal of knee surgery. Jun 2019;32(6):490-498. doi:10.1055/s-0038-1653943
  • 15. Hohmann E. Editorial Commentary: Discovery: Progenitor Cells and Endothelial Cells Are Found in the White-White Zone of the Meniscus, But This Does Not Mean That These Tears Heal or Should Be Repaired. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Jan 2021;37(1):266-267. doi:10.1016/j.arthro.2020.11.007
  • 16. Bahcecioglu G, Bilgen B, Hasirci N, Hasirci V. Anatomical meniscus construct with zone specific biochemical composition and structural organization. Biomaterials. Oct 2019;218:119361. doi:10.1016/j.biomaterials.2019.119361
  • 17. Cinque ME, DePhillipo NN, Moatshe G, et al. Clinical Outcomes of Inside-Out Meniscal Repair According to Anatomic Zone of the Meniscal Tear. Orthopaedic journal of sports medicine. Jul 2019;7(7):2325967119860806. doi:10.1177/2325967119860806
  • 18. Angele P, Docheva D, Pattappa G, Zellner J. Cell-based treatment options facilitate regeneration of cartilage, ligaments and meniscus in demanding conditions of the knee by a whole joint approach. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. Apr 2022;30(4):1138-1150. doi:10.1007/s00167-021-06497-9
  • 19. Kwon H, Brown WE, Lee CA, et al. Surgical and tissue engineering strategies for articular cartilage and meniscus repair. Nature reviews Rheumatology. Sep 2019;15(9):550-570. doi:10.1038/s41584-019-0255-1
  • 20. Rhim HC, Jeon OH, Han SB, Bae JH, Suh DW, Jang KM. Mesenchymal stem cells for enhancing biological healing after meniscal injuries. World journal of stem cells. Aug 26 2021;13(8):1005-1029. doi:10.4252/wjsc.v13.i8.1005
  • 21. Barber-Westin SD, Noyes FR. Clinical healing rates of meniscus repairs of tears in the central-third (red-white) zone. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Jan 2014;30(1):134-46. doi:10.1016/j.arthro.2013.10.003
  • 22. Mordecai SC, Al-Hadithy N, Ware HE, Gupte CM. Treatment of meniscal tears: An evidence based approach. World journal of orthopedics. Jul 18 2014;5(3):233-41. doi:10.5312/wjo.v5.i3.233
  • 23. Bansal S, Floyd ER. Meniscal repair: The current state and recent advances in augmentation. Jul 2021;39(7):1368-1382. doi:10.1002/jor.25021
  • 24. Lin KM, Gadinsky NE, Klinger CE, et al. Increased Vascularity in the Neonatal versus Adult Meniscus: Evaluation with Magnetic Resonance Imaging. Cartilage. Dec 2021;13(2_suppl):1562s-1569s. doi:10.1177/1947603520923143
  • 25. Wu M, Su Q, Zhao Q, Liu S. Evidence-based weight-bearing protocols after meniscal repair: balancing functional recovery and healing safety across injury types. Journal of orthopaedic surgery and research. Jun 19 2025;20(1):604. doi:10.1186/s13018-025-05988-6
  • 26. Berzolla E, Sundaram V, Strauss E. A Review of Revision Meniscal Repair: Clinical Considerations and Outcomes. Current reviews in musculoskeletal medicine. Sep 2025;18(9):344-352. doi:10.1007/s12178-025-09968-5
  • 27. Kamaci S, Pace JL. Redefining Failure: Criteria for Unsuccessful Outcomes in Meniscus Repair. Current reviews in musculoskeletal medicine. Sep 2025;18(9):353-360. doi:10.1007/s12178-025-09971-w
  • 28. Gallacher P, Gilbert R, Kanes G, Roberts S, Rees D. White on white meniscal tears to fix or not to fix? The Knee. 2010;17(4):270-273.
  • 29. Oeding JF, Berlinberg EJ, Lu Y, et al. Platelet-Rich Plasma and Marrow Venting May Serve as Cost-Effective Augmentation Techniques for Isolated Meniscal Repair: A Decision-Analytical Markov Model-Based Analysis. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Sep 2023;39(9):2058-2068. doi:10.1016/j.arthro.2023.02.018
  • 30. Paxton ES, Stock MV, Brophy RH. Meniscal repair versus partial meniscectomy: a systematic review comparing reoperation rates and clinical outcomes. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Sep 2011;27(9):1275-88. doi:10.1016/j.arthro.2011.03.088
Toplam 30 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Ortopedi
Bölüm Araştırma Makalesi
Yazarlar

Yunus Emre Bulum 0000-0001-5568-8170

Mehmet Arıcan 0000-0002-0649-2339

Zekeriya Okan Karaduman 0000-0002-6719-3666

Mücahid Osman Yücel 0000-0002-9405-2367

Raşit Emin Dalaslan 0000-0001-5068-8024

Sönmez Sağlam 0000-0003-2651-8003

Gönderilme Tarihi 30 Ekim 2025
Kabul Tarihi 28 Şubat 2026
Yayımlanma Tarihi 15 Mart 2026
DOI https://doi.org/10.26453/otjhs.1813497
IZ https://izlik.org/JA93AY29EP
Yayımlandığı Sayı Yıl 2026 Cilt: 11 Sayı: 1

Kaynak Göster

AMA 1.Bulum YE, Arıcan M, Karaduman ZO, Yücel MO, Dalaslan RE, Sağlam S. Vascular Zone Matters: Clinical Outcomes of Arthroscopic Meniscal Repair in Red–Red, Red–White, and White–White Tears. OTSBD. 2026;11(1):24-31. doi:10.26453/otjhs.1813497

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