Akut ve Kronik Ürtiker Hastalarında Platelet Belirteçlerinin, C-Reaktif Protein Düzeyleri ve Hastalık Şiddeti ile Karşılaştırılması

Öz

Bu çalışmada; akut ve kronik ürtikerli hastalarda, platelet belirteçlerini ve C-reaktif protein düzeyleri ölçülmüştür. Ürtiker patogenezinde plateletlerin rolünü araştırmak amaçlandı. Çalışmaya 18-76 yaş arasında 34 akut ürtiker hastası, 27 kronik ürtiker hastası ve 30 sağlıklı gönüllü alınmıştır. Gruplar arasında demografik veriler açısından anlamlı fark saptanmamıştır. Platelet belirteçlerinden MPV ve PDW değerlerinde akut ürtiker ve kronik ürtiker grubu arasında fark saptanmaz iken, kontrol grubunda bu değerler istatistiksel olarak anlamlı yüksek bulundu (p<0,001).  Kontrol grubunda CRP değeri istatistiksel olarak anlamlı düşük bulundu (p:0,008). Ürtiker patogenezinde plateletlerin rolünün daha iyi anlaşılması için geniş hasta serilerinde çalışmalara gereksinim vardır.

Anahtar Kelimeler

• ürtiker,c-reaktif protein,kronik ürtiker,akut ürtiker

Comparison of Platelet Markers with C-Reactive Protein Levels and Disease Severity at Patients with Acute and Chronic Urticaria

Abstract

In this study; Platelet markers and C-reactive protein levels were measured in patients with acute and chronic urticaria. The aim of this study was to investigate the role of platelets in the pathogenesis of urticaria.  The study included 34 acute urticaria patients, 27 chronic urticaria patients and 30 healthy volunteers between the ages of 18-76. There was no significant difference between the groups in terms of demographic data. MPV and PDW values of platelet markers were not significantly different between acute urticaria and chronic urticaria group (p<0.001). CRP values were significantly lower in the control group (p:0.008). In order to better understand the role of platelets in the pathogenesis of urticaria, large series of patients are needed.

Keywords

• urticaria,platelets,C-reactive protein,Chronic Urticaria

Kaynakça

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