Nanotechnology and Nanobiomaterials: Redefining Ways of Managing Oral Cancer

Öz

Nano-biotechnology can be considered as application of various nanotechnologies in the biological field. With the advent of nano-particles, a revolution has come in the scientific community. The convergence of nanotechnology and medicine recently led to an interdisciplinary field, nanomedicine, which brings together engineers, physicists, biologists, chemists, mathematicians, and physicians striving to improve detection, imaging, and drug-delivery devices. The approaches to nanomedicine range from the medical use of nanomaterials, to nanoelectronics biosensors, and even possible future applications of molecular nanotechnology. Cancer is a leading cause of mortality in the world. Cancers of the head and neck—including the salivary glands, thyroid, and the mucosal lining of the oral cavity, pharynx, nasopharynx, and larynx—account for the high percentage of malignancies of the world. At present the treatment modalities available are very limited. A multidisciplinary approach is needed, including the cooperation of biophysics experts, molecular biologists and medical practitioners, to find ways of using nano-biotechnologies for cancer management. Hence future research needs to focus on designing new strategies where nano-biomaterials and medicine can come together to find a cure.

Anahtar Kelimeler

• Oral squamous cell carcinoma
• Nano-biotechnology
• malignancies
• nano particles

Nanoteknoloji ve Nanobiyomalzemeler: Ağız Kanserini Yönetme Yollarını Yeniden Tanımlama

Öz

Nano-biyoteknoloji, biyolojik alanda çeşitli nanoteknolojilerin uygulaması olarak düşünülebilir. Nano parçacıkların ortaya çıkmasıyla, bilim camiasında bir devrim gerçekleşti. Nanoteknoloji ve tıbbın yakınlaşması, son zamanlarda disiplinler arası bir alana, yani nanotıpa yol açtı; bu, algılama, görüntüleme ve ilaç dağıtım cihazlarını iyileştirmeye çalışan mühendisleri, fizikçileri, biyologları, kimyagerleri, matematikçileri ve doktorları bir araya getirdi. Kanser, dünyadaki ölümlerin önde gelen nedenidir. Tükürük bezleri, tiroid, ağız boşluğu, yutak, nazofarenks ve gırtlak dahil olmak üzere baş ve boyun kanserleri, dünyadaki kanser vakalarının yüksek yüzdesini oluşturur. Şu anda mevcut tedavi modaliteleri çok sınırlıdır. Kanser yönetimi için nano-biyoteknolojileri kullanmanın yollarını bulmak için biyofizik uzmanları, moleküler biyologlar ve tıp pratisyenlerinin işbirliğini içeren multidisipliner bir yaklaşıma ihtiyaç vardır. Bu nedenle bir tedavi bulmak için nano biyomalzeme ve tıbbın bir araya gelebileceği yeni stratejiler tasarlamaya odaklanılması gerekiyor.

Anahtar Kelimeler

• Maligniteler
• nano-biyoteknoloji
• nano partiküller
• oral skuamöz hücreli karsinom

Kaynakça

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