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Hepatit C tedavisinde 2016 sağlık uygulama tebliğinin getirdiği yenilikler

Year 2016, Volume: 1 Issue: 2, 23 - 29, 28.06.2016

Abstract

Hepatit c tedavisindeki başarı direkt etkili oral antivirallerle %90’ları aşmaktadır. Geri ödeme kapsamındaki ilaçlar ülkeden ülkeye değişiklik göstermektedir. Ülkemizde iki farklı kombinasyon (sofosbuvir-ledipasvir  ve ombitasvir-paritaprevir- ritonavir- dasabuvir) Haziran 2016’dan itibaren geri ödeme kapsamına alındı. Bununla birlikte bu kombinasyonlarla ilgili düzenlemeler kronik hepatit C tedavisinde yeni şartlar ve sınırlamalar getirdi. Bu derlemede ülkemizdeki hepatit c tedavi şemaları ve geri ödeme şartları eski ve yeni kurallarıyla gözden geçirilmiştir.

References

  • http://www.resmigazete.gov.tr/default.aspx (Erişim tarihi:23.06.2016).
  • Tosun S . Viral hepatitlerin ülkemizdeki değişen epidemiyolojisi. ANKEM Derg 2013;27(Ek 2):128-134.
  • Chen SL. The Natural History of Hepatitis C Virus (HCV) Infection. International Journal of Medical Sciences Int J Med Sci 2006;3(2):47-52.
  • Sarasin-Filipowicz M. Interferon therapy of hepatitis C: molecular insights
  • into success and failure. Swiss Med Wkly. 2010 Jan 9;140(1-2):3-11.
  • American Association for the study of liver diseases (AASLD) and Infectious Diseases Society of America (IDSA). HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C http://www.hcvguidelines.org (Erişim tarihi: 22.06.2016).
  • Zhu Y, Chen S. Antiviral treatment of hepatitis C virus infection and factors
  • affecting efficacy. World J Gastroenterol. 2013 Dec 21;19(47):8963-73.
  • Afdhal N, Zeuzem S, Kwo P, et al. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med. 2014 May 15;370(20):1889-98.
  • Feld JJ, Kowdley KV, Coakley E, et al. Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med 2014; 370: 1594–603.
  • Holmes JA, Thompson AJ. Interferon-free combination therapies fort he treatment of hepatitis C: current insights. Hepat Med. 2015 Nov 2;7:51-70.
Year 2016, Volume: 1 Issue: 2, 23 - 29, 28.06.2016

Abstract

References

  • http://www.resmigazete.gov.tr/default.aspx (Erişim tarihi:23.06.2016).
  • Tosun S . Viral hepatitlerin ülkemizdeki değişen epidemiyolojisi. ANKEM Derg 2013;27(Ek 2):128-134.
  • Chen SL. The Natural History of Hepatitis C Virus (HCV) Infection. International Journal of Medical Sciences Int J Med Sci 2006;3(2):47-52.
  • Sarasin-Filipowicz M. Interferon therapy of hepatitis C: molecular insights
  • into success and failure. Swiss Med Wkly. 2010 Jan 9;140(1-2):3-11.
  • American Association for the study of liver diseases (AASLD) and Infectious Diseases Society of America (IDSA). HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C http://www.hcvguidelines.org (Erişim tarihi: 22.06.2016).
  • Zhu Y, Chen S. Antiviral treatment of hepatitis C virus infection and factors
  • affecting efficacy. World J Gastroenterol. 2013 Dec 21;19(47):8963-73.
  • Afdhal N, Zeuzem S, Kwo P, et al. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med. 2014 May 15;370(20):1889-98.
  • Feld JJ, Kowdley KV, Coakley E, et al. Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med 2014; 370: 1594–603.
  • Holmes JA, Thompson AJ. Interferon-free combination therapies fort he treatment of hepatitis C: current insights. Hepat Med. 2015 Nov 2;7:51-70.
There are 11 citations in total.

Details

Journal Section Review article
Authors

Aziz Öğütlü This is me

Oğuz Karabay

Ertuğrul Güçlü

Publication Date June 28, 2016
Submission Date June 24, 2016
Published in Issue Year 2016 Volume: 1 Issue: 2

Cite

AMA Öğütlü A, Karabay O, Güçlü E. Hepatit C tedavisinde 2016 sağlık uygulama tebliğinin getirdiği yenilikler. OTJHS. June 2016;1(2):23-29.

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