Yüksek vücut kitle indeksi, sağ lob canlı donörden karaciğer nakli alıcılarında postoperatif kanama ve safra komplikasyon oranlarını artıran bir faktör mü?

Öz

Amaç: Yüksek Vücut Kitle İndeksi, karaciğer transplantasyonu için önemli bir perioperatif ve postoperatif risk faktörü olarak ortaya çıkmaktadır. Karaciğer transplantasyonu alıcılarında artmış BMI'nin perioperatif takip parametreleri ve postoperatif komplikasyonlar üzerine etkisini incelemeyi amaçladık. Gereç ve yöntem: Son dönem karaciğer sirozu nedeniyle canlı vericiden karaciğer nakli yapılan 172 hasta çalışmaya dahil edildi. Bunlara göre soğuk iskemi süresi, operasyon süresi, kan ürünü transfüzyon oranları, hastane yatış süresi, safra komplikasyonları, hepatik ven trombozu, portal ven trombozu, NASH etiyolojisi, postoperatif kanama, sepsis ve primer greft disfonksiyonu arasında fark olup olmadığı BMI'sı 25 ve üzeri olan ve 25'in altında olan kişiler açısından istatistiksel olarak analiz edildi. Bulgular: BMI >25 olan hastalarda anhepatik faz süresi (p=0,047) ve soğuk iskemi süresi (p=0,009) istatistiksel olarak daha uzundu. Sonuç: Uzamış anhepatik faz ve soğuk iskemi süreleri, artan vücut kitle indeksinin postoperatif greft sağ kalımına etkisi açısından önemli olabilir.

Anahtar Kelimeler

• Obezite
• vücut kitle indeksi
• karaciğer
• transplantasyon
• komplikasyon

Is high body mass index a factor that increases postoperative hemorrhage and bile complication rates in right lobe living donor liver transplant recipients?

Öz

Purpose: High Body Mass Index emerges as an important perioperative and postoperative risk factor for liver transplantation. We aimed to examine the effect of increased BMI on perioperative follow-up parameters and per-postoperative complications in liver transplant recipients. Materials and methods: One hundred and seventy-two patients who underwent living-donor liver transplantation for end stage liver cirrhosis were included in the study. Whether there was a difference between cold ischemia time, operation time, blood product transfusion rates, hospital, biliary complications, hepatic vein thrombosis, portal vein thrombosis, NASH etiology, postoperative hemorrhage, sepsis, and primary graft dysfunction were analyzed statistically in terms of those with a BMI of 25 and above and those below 25. Results: Anhepatic phase duration (p=0.047) and cold ischemia duration (p=0.009) were statistically longer in patients with BMI >25. Conclusion: Prolonged anhepatic phase and cold ischemia times may be important in terms of the effect of increased BMI on postoperative graft survival.

Anahtar Kelimeler

• Obesity
• body mass index
• liver
• transplantation
• complication

Kaynakça

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