Pediatric pineal and tectal region tumors: the use of neuroendoscopy
Öz
Purpose: In this article, we aimed to contribute to the literature by describing our approach to pediatric pineal
and tectal masses treated with endoscopic interventions in our clinic.
Materials and methods: We retrospectively reviewed the records of 26 patients with lesions in the pineal and
tectal regions who underwent endoscopic procedures between 2012 and 2023 at Gazi University Department
of Pediatric Neurosurgery. Demographic data, blood tumor markers (alpha fetoprotein-BETA AFP, alpha
fetoprotein-β-hCG), pathological diagnoses, reasons for clinical presentation, presence of hydrocephalus and
additional interventions were analyzed.
Results: Of the 26 patients who underwent endoscopic procedure, 6 had lesions in the pineal region and 20
had lesions in the tectal region. The success rate for ETV was 75-80%. The success rate for ETV was 78.3%
for patients with tumors in the pineal region and 84% for tectal tumors.
Conclusion: Pineal or tectal region tumors are a rare group of tumors. In addition, these regions are among
the most heterogeneous regions in the central nervous system in terms of tumor type and histology. Endoscopic
intervention through a single burr hole using rigid endoscopy is a comfortable and safe minimally invasive
method for both pathologic sampling and management of hydrocephalus in indicated cases in the same session.
Anahtar Kelimeler
Pediatric tumors, pineal tumors, tectal tumors, neuroendoscopy
Destekleyen Kurum
Gazi UNIVERSITY
Proje Numarası
6e27d218-19d0-4594-a3a3-5b3f63ac37b3
Kaynakça
- 1. Bruce JN, Ogden AT. Surgical strategies for treating patients with pineal region tumors. J Neurooncol 2004;69:221-236. https://doi.org/10.1023/b:neon.0000041885.09226.2d
- 2. Ostrom QT, Gittleman H, Xu J, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the united States in 2009-2013. Neuro Oncol 2016;18:1-75. https://doi.org/10.1093/neuonc/now207
- 3. Ezzat S, Kamal M, El Khateeb N, et al. Pediatric brain tumors in a low/middle income country: does it differ from that in developed world? J Neurooncol 2016;126:371-376. https://doi.org/10.1007/s11060-015-1979-7
- 4. Hu J, Western S, Kesari S. Brainstem Glioma in Adults. Front Oncol 2016;6:180(e1-7). https://doi.org/10.3389/fonc.2016.00180
- 5. Ahmed AI, Zaben MJ, Mathad NV, Sparrow OCE. Endoscopic biopsy and third ventriculostomy for the management of pineal region tumors World Neurosurg 2015;83:543-547. https://doi.org/10.1016/j.wneu.2014.11.013
- 6. O’Brien DF, Hayhurst C, Pizer B, Mallucci CL. Outcomes in patients undergoing single-trajectory endoscopic third ventriculostomy and endoscopic biopsy for midline tumors presenting with obstructive hydrocephalus. J Neurosurg 2006;105:219-226. https://doi.org/10.3171/ped.2006.105.3.219
- 7. Sahana D, Rathore L, Kumar S, Sahu RK. Endoscopic anatomy of lateral and third ventricles: a must know for performing endoscopic third ventriculostomy. Neurol India 2021;69:45-48. https://doi.org/10.4103/0028-3886.310075
- 8. Tien RD, Barkovich AJ, Edwards MS. MR imaging of pineal tumors. AJR Am J Roentgenol 1990;155:143-151. https://doi.org/10.2214/ajr.155.1.2162137
- 9. Fukushima T. Endoscopic biopsy of intraventricular tumors with the use of a ventriculofiberscope. Neurosurgery 1978;2:110-113. https://doi.org/10.1227/00006123-197803000-00006
- 10. Grant GA, Avellino AM, Loeser JD, Ellenbogen RG, Berger MS, Roberts TS. Management of intrinsic gliomas of the tectal plate in children: a ten-year review. Pediatr Neurosurg 1999;31:170-176. https://doi.org/10.1159/000028857
