A rare neurological manifestation of seizure in a case of anaphylaxis following a hornet sting: case report & literature review
Öz
Anaphylaxis is a severe, life-threatening allergic reaction that can present with a variety of systemic manifestations. Neurological symptoms such as seizures or seizure-like activity are uncommon in anaphylaxis. We present the case of a healthy young male with no history of seizures who experienced anaphylaxis following a hornet sting, manifested by urticarial rashes, facial flushing, and generalized pruritus. Interestingly, he developed seizure-like activity, characterized by focal jerky movement of the left upper limb with impaired consciousness as reported by eyewitnesses. This case highlights the atypical presentation of neurological manifestations of anaphylaxis, discusses its potential pathophysiological mechanisms, and reflecting individualized management approach in relation to established guidelines.
Anahtar Kelimeler
Anaphylaxis, wasp sting, hornet sting, seizure, neurological manifestations
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Proje Numarası
Etik Beyan
Teşekkür
Kaynakça
- Simons FE, Ardusso LR, Bilò MB, et al. World Allergy Organization anaphylaxis guidelines: summary. J Allergy Clin Immunol. 2011;127(3):587-593e22. doi:10.1016/j.jaci.2011.01.038
- Lieberman P, Nicklas RA, Randolph C, et al. Anaphylaxis--a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115(5):341-384. doi:10.1016/j.anai.2015.07.019
- Pumphrey RS. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy. 2000;30(8):1144-1150. doi:10.1046/j.1365-2222.2000.00864.x
- Worm M, Francuzik W, Renaudin JM, et al. Factors increasing the risk for a severe reaction in anaphylaxis: An analysis of data from The European Anaphylaxis Registry. Allergy. 2018;73(6):1322-1330. doi:10.1111/all.13380
- Golden DB. Insect sting anaphylaxis. Immunol Allergy Clin North Am. 2007;27(2):261-vii. doi:10.1016/j.iac.2007.03.008
- Turner PJ, Campbell DE, Boyle RJ, Levin ME. Primary Prevention of Food Allergy: Translating Evidence from Clinical Trials to Population-Based Recommendations. J Allergy Clin Immunol Pract. 2018;6(2):367-375. doi:10.1016/j.jaip.2017.12.015
- Kemp SF, Lockey RF, Simons FE; World Allergy Organization ad hoc Committee on Epinephrine in Anaphylaxis. Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy Organization. Allergy. 2008;63(8):1061-1070. doi:10.1111/j.1398-9995.2008.01733.x
- Schwartz LB. Diagnostic value of tryptase in anaphylaxis and mastocytosis. Immunol Allergy Clin North Am. 2006;26(3):451-463. doi:10.1016/j.iac.2006.05.010
- Kharal GA, Darby RR, Cohen AB. Envenomation seizures. Neurohospitalist. 2018;8(1):29-30. doi:10.1177/1941874417737016
- Banks WA. The blood-brain barrier in neuroimmunology: Tales of separation and assimilation. Brain Behav Immun. 2015;44:1-8. doi:10.1016/j.bbi.2014.08.007
