Araştırma Makalesi

Valsalva-induced anterior segment changes in phakic and pseudophakic eyes

Cilt: 19 Sayı: 4 10 Ekim 2026
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Valsalva-induced anterior segment changes in phakic and pseudophakic eyes

Öz

Purpose: To evaluate anterior segment changes induced by the Valsalva maneuver in phakic and pseudophakic eyes using Scheimpflug imaging.
Materials and methods: This paired-eye cross-sectional observational study included 136 eyes of 68 patients with unilateral pseudophakia, with each participant contributing one pseudophakic eye and the contralateral phakic eye. Intraocular pressure (IOP), central corneal thickness (CCT), corneal volume (CV), anterior chamber depth (ACD), anterior chamber volume (ACV), pupil diameter (PD), iridocorneal angle (ICA), axial length (AL), and the ACD/AL ratio were measured at baseline and during a standardized Valsalva maneuver. Measurements were obtained using non-contact tonometry, Scheimpflug imaging, and optical biometry. Within-eye changes from baseline were analyzed separately for phakic and pseudophakic eyes.
Results: During the Valsalva maneuver, IOP and PD increased significantly in both phakic and pseudophakic eyes (all p≤0.003). In phakic eyes, ACD and ACV decreased significantly (both p=0.03), whereas ICA did not change significantly (p=0.58). In pseudophakic eyes, ICA decreased significantly (p=0.002), whereas the changes in ACD and ACV were not statistically significant (p=0.08 and p=0.61, respectively). No statistically significant changes were detected in AL, CV, or the ACD/AL ratio in either group. CCT changes did not reach the predefined threshold for statistical significance.
Conclusions: The Valsalva maneuver was associated with transient changes in intraocular pressure, pupil diameter, and selected anterior segment parameters in both phakic and pseudophakic eyes. Within-eye analyses showed significant reductions in ACD and ACV in phakic eyes and significant narrowing of the ICA in pseudophakic eyes. However, direct comparison of these changes between lens-status groups is required before concluding that phakic and pseudophakic eyes exhibit different biomechanical responses. Standardization of respiratory effort may improve the reliability of anterior segment imaging and biometric measurements.

Anahtar Kelimeler

Destekleyen Kurum

Pamukkale University

Etik Beyan

Ethical approval for this study was obtained from the Non-Interventional Clinical Research Ethics Committee of Pamukkale University (Approval No: E-60116787-020-761878, Date: 30.09.2025).

Teşekkür

Pamukkale University

Kaynakça

  1. References 1. Zebrowska, A., Gasior, Z., & Jastrzebski, D. (2013). Cardiovascular effects of the valsalva maneuver during static arm exercise in elite power lifting athletes. Advances in experimental medicine and biology, 755, 335–342. https://doi.org/10.1007/978-94-007-4546-9_42
  2. 2. Pstras, L., Thomaseth, K., Waniewski, J., Balzani, I., & Bellavere, F. (2016). The Valsalva manoeuvre: physiology and clinical examples. Acta physiologica (Oxford, England), 217(2), 103–119. https://doi.org/10.1111/apha.12639
  3. 3. Ozcan, S. C., Kurtul, B. E., & Ozarslan Ozcan, D. (2020). Evaluation of microvascular changes in optic disc and retina by optical coherence tomography angiography during Valsalva maneuver. International ophthalmology, 40(10), 2743–2749. https://doi.org/10.1007/s10792-020-01461-x
  4. 4. Çiçek, A., Duru, N., Duru, Z., Altunel, O., Haşhaş, A. S. K., Arifoğlu, H. B., Alabay, B., & Ataş, M. (2017). The assessment of choroidal thickness with spectral-domain optical coherence tomography during Valsalva maneuver. International ophthalmology, 37(4), 843–848. https://doi.org/10.1007/s10792-016-0340-2
  5. 5. Mete, A., Kimyon, S., Saygılı, O., Evişen, A., Pamukcu, C., Çeri, S., & Güngör, K. (2016). Dynamic changes in optic disc morphology, choroidal thickness, anterior chamber parameters, and intraocular pressure during Valsalva maneuver. Arquivos brasileiros de oftalmologia, 79(4), 209–213. https://doi.org/10.5935/0004-2749.20160061
  6. 6. Pekel, G., Acer, S., Yagci, R., Kaya, H., & Pekel, E. (2014). Impact of Valsalva maneuver on corneal morphology and anterior chamber parameters. Cornea, 33(3), 271–273. https://doi.org/10.1097/ICO.0000000000000046
  7. 7. Wiest, M. R. J., Hamann, T., & Zweifel, S. (2022). Effect of Valsalva Maneuver on Choriocapillary Retinal Microvasculature. Der Effekt des Valsalva-Manövers auf die choriokapilläre retinale Microvaskulatur. Klinische Monatsblatter fur Augenheilkunde, 239(4), 523–526. https://doi.org/10.1055/a-1766-6071
  8. 8. Mutaf, Ç., Uzun, I., Reyhan, A. H., & Yüksekyayla, F. (2025). An evaluation of anterior segment and corneal changes during the valsalva maneuver in keratoconus patients with and without corneal cross-linking. International ophthalmology, 45(1), 224. https://doi.org/10.1007/s10792-025-03618-y

Ayrıntılar

Birincil Dil

İngilizce

Konular

Göz Hastalıkları

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

10 Ekim 2026

Gönderilme Tarihi

29 Temmuz 2026

Kabul Tarihi

9 Ekim 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 19 Sayı: 4

Kaynak Göster

APA
Şeker Ün, E., Akyol, T., Parça, O., Pekel, G., Bahar, A., & Akbulut, S. (2026). Valsalva-induced anterior segment changes in phakic and pseudophakic eyes. Pamukkale Medical Journal, 19(4), 850-860. https://doi.org/10.31362/patd.2005003
AMA
1.Şeker Ün E, Akyol T, Parça O, Pekel G, Bahar A, Akbulut S. Valsalva-induced anterior segment changes in phakic and pseudophakic eyes. Pam Tıp Derg. 2026;19(4):850-860. doi:10.31362/patd.2005003
Chicago
Şeker Ün, Emine, Tunahan Akyol, Osman Parça, Gökhan Pekel, Alperen Bahar, ve Selen Akbulut. 2026. “Valsalva-induced anterior segment changes in phakic and pseudophakic eyes”. Pamukkale Medical Journal 19 (4): 850-60. https://doi.org/10.31362/patd.2005003.
EndNote
Şeker Ün E, Akyol T, Parça O, Pekel G, Bahar A, Akbulut S (01 Ekim 2026) Valsalva-induced anterior segment changes in phakic and pseudophakic eyes. Pamukkale Medical Journal 19 4 850–860.
IEEE
[1]E. Şeker Ün, T. Akyol, O. Parça, G. Pekel, A. Bahar, ve S. Akbulut, “Valsalva-induced anterior segment changes in phakic and pseudophakic eyes”, Pam Tıp Derg, c. 19, sy 4, ss. 850–860, Eki. 2026, doi: 10.31362/patd.2005003.
ISNAD
Şeker Ün, Emine - Akyol, Tunahan - Parça, Osman - Pekel, Gökhan - Bahar, Alperen - Akbulut, Selen. “Valsalva-induced anterior segment changes in phakic and pseudophakic eyes”. Pamukkale Medical Journal 19/4 (01 Ekim 2026): 850-860. https://doi.org/10.31362/patd.2005003.
JAMA
1.Şeker Ün E, Akyol T, Parça O, Pekel G, Bahar A, Akbulut S. Valsalva-induced anterior segment changes in phakic and pseudophakic eyes. Pam Tıp Derg. 2026;19:850–860.
MLA
Şeker Ün, Emine, vd. “Valsalva-induced anterior segment changes in phakic and pseudophakic eyes”. Pamukkale Medical Journal, c. 19, sy 4, Ekim 2026, ss. 850-6, doi:10.31362/patd.2005003.
Vancouver
1.Emine Şeker Ün, Tunahan Akyol, Osman Parça, Gökhan Pekel, Alperen Bahar, Selen Akbulut. Valsalva-induced anterior segment changes in phakic and pseudophakic eyes. Pam Tıp Derg. 01 Ekim 2026;19(4):850-6. doi:10.31362/patd.2005003

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