Yıl 2020, Cilt 13 , Sayı 2, Sayfalar 341 - 349 2020-05-14

Purpose: The aim of this study is to determine whether the parameters that are not included in the criteria of metabolic syndrome and which are considered as indicators of adiposity, differ between women with and without metabolic syndrome and to determine the cut-off points predicting metabolic syndrome. Materials and Methods: A total of 393 adult women without glucose metabolism disorder were included. After determining the participants with and without metabolic syndrome, anthropometric measurements and body fat distribution of all participants were measured and laboratory parameters were examined. The ROC curves were plotted and the areas under the curve were calculated. The cut-off points predicting metabolic syndrome and the sensitivity and specificity ratios of these cut-off points were determined. Results: While the area under the curve for body mass index, neck circumference, visceral fat level, body fat percentage, HOMAIR index and insulin levels was found to be over 0.7, area under the curve for hip circumference, waist-hip ratio, total fat mass and total fat percentage, and LDL-C and TSH levels were below 0.7. The cut-off points of parameters that predict metabolic syndrome for women were found to be 27.7 kg/m2 for body mass index, 33.8 cm for neck circumference, 91.5 cm for waist circumference, 10.8 for visceral fat, 43.1% for trunk fat percentage, 2.14 for HOMAIR index and 8.7 µU/mL for insulin levels. Conclusion: Body mass index, neck circumference, visceral fat level, body fat percentage, HOMAIR index and insulin levels are valuable criteria to predict metabolic syndrome.
Amaç: Metabolik sendrom kriterler içinde yer almayan ve adipozite göstergesi kabul edilen parametrelerin, metabolik sendromu olan ve olmayan kadınlar arasında farklılık gösterip göstermediğini ortaya koymak ve bu parametrelerin metabolik sendromu predikte eden kesim noktalarını saptamak amaçlanmıştır. Gereç ve Yöntem: Kilo vermek için başvuran, bilinen glikoz metabolizma bozukluğu olmayan 393 kadın birey (18-70 yaş) alındı. Bu bireylerden NCEP ATPIII kriterlerine göre metabolik sendromu olan ve olmayanlar tespit edildikten sonra, tüm katılımcıların antropometrik ölçümleri ve vücut yağ dağılımı ölçüldü ve laboratuar parametrelerine bakıldı. ROC eğrileri çizildi ve eğri altındaki alanlar hesaplandı ve parametrelerin metabolik sendromu predikte eden kesim noktaları ve bu kesim noktalarının duyarlılık ve özgüllük oranları belirlendi. Bulgular: Metabolik sendromu predikte eden parametrelerden, vücut kitle indeksi, boyun çevresi, visseral yağ miktarı, gövde yağ yüzdesi, HOMAIR indeksi ve insülin düzeylerinin, eğri altındaki alanları 0,7'nin üstünde olduğu; kalça çevresi, bel-kalça oranı, konvansiyonel BİA ile ölçülen total yağ kitlesi ve yağ yüzdesinin, LDL-K ve TSH düzeyinin ise 0,7'nin altında olduğu saptanmıştır. Vücut kitle indeksi için 27,7 kg/m2, boyun çevresi için 33,8 cm, bel çevresi için 91,5 cm, visseral yağ miktarı için 10,8 birim, gövde yağ yüzdesi için %43,1, HOMAIR indeksi için 2,14 ve insülin düzeyi için 8,7 µU/mL değerlerinin metabolik sendromu predikte etmedeki duyarlılıkları %80 ve üstünde bulunmuştur. Sonuç: Vücut kitle indeksi, boyun çevresi, visseral yağ miktarı, gövde yağ yüzdesi, HOMAIR indeksi ve insülin düzeyleri metabolik sendromun alternatif prediktörü olarak kullanılabilecek pratik ve değerli ölçütlerdir.
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Birincil Dil tr
Konular Endokrinoloji ve Metabolizma
Yayımlanma Tarihi Mayıs 2020
Bölüm Araştırma Makalesi
Yazarlar

Orcid: 0000-0002-6976-6659
Yazar: Yusuf BOZKUŞ (Sorumlu Yazar)
Kurum: BAŞKENT ÜNİVERSİTESİ
Ülke: Turkey


Orcid: 0000-0002-8078-9376
Yazar: Umut MOUSA
Kurum: DR. BURHAN NALBANTOĞLU DEVLET HASTANESİ ,KKTC
Ülke: KKTC


Orcid: 0000-0001-7103-9963
Yazar: Nazlı GÜLSOY KİRNAP
Kurum: BAŞKENT ÜNİVERSİTESİ
Ülke: Turkey


Orcid: 0000-0001-5305-6807
Yazar: Özlem TURHAN İYİDİR
Kurum: BAŞKENT ÜNİVERSİTESİ
Ülke: Turkey


Orcid: 0000-0002-4141-6163
Yazar: Lala RAMAZANOVA
Kurum: BAŞKENT ÜNİVERSİTESİ
Ülke: Turkey


Orcid: 0000-0003-0998-8388
Yazar: Aslı NAR
Kurum: BAŞKENT ÜNİVERSİTESİ
Ülke: Turkey


Orcid: 0000-0002-1816-3903
Yazar: Neslihan BAŞÇIL TÜTÜNCÜ
Kurum: BAŞKENT ÜNİVERSİTESİ
Ülke: Turkey


Destekleyen Kurum Başkent Üniversitesi Araştırma Fonu
Proje Numarası KA19-405
Teşekkür Bu çalışma Başkent Üniversitesi Tıp ve Sağlık Bilimleri Araştırma Kurulu tarafından onaylanmış ve Başkent Üniversitesi Araştırma Fonunca desteklenmiştir.
Tarihler

Yayımlanma Tarihi : 14 Mayıs 2020

Bibtex @araştırma makalesi { patd662692, journal = {Pamukkale Tıp Dergisi}, issn = {}, eissn = {1308-0865}, address = {Pamukkale Üniversitesi Tıp Fakültesi Eğitim Blokları Kınıklı kampüsü 20070 Kınıklı, Denizli}, publisher = {Pamukkale Üniversitesi}, year = {2020}, volume = {13}, pages = {341 - 349}, doi = {10.31362/patd.662692}, title = {Kadınlarda metabolik sendromun alternatif prediktörleri}, key = {cite}, author = {BOZKUŞ, Yusuf and MOUSA, Umut and GÜLSOY KİRNAP, Nazlı and TURHAN İYİDİR, Özlem and RAMAZANOVA, Lala and NAR, Aslı and BAŞÇIL, Neslihan} }
APA BOZKUŞ, Y , MOUSA, U , GÜLSOY KİRNAP, N , TURHAN İYİDİR, Ö , RAMAZANOVA, L , NAR, A , BAŞÇIL, N . (2020). Kadınlarda metabolik sendromun alternatif prediktörleri. Pamukkale Tıp Dergisi , 13 (2) , 341-349 . DOI: 10.31362/patd.662692
MLA BOZKUŞ, Y , MOUSA, U , GÜLSOY KİRNAP, N , TURHAN İYİDİR, Ö , RAMAZANOVA, L , NAR, A , BAŞÇIL, N . "Kadınlarda metabolik sendromun alternatif prediktörleri". Pamukkale Tıp Dergisi 13 (2020 ): 341-349 <https://dergipark.org.tr/tr/pub/patd/issue/54327/662692>
Chicago BOZKUŞ, Y , MOUSA, U , GÜLSOY KİRNAP, N , TURHAN İYİDİR, Ö , RAMAZANOVA, L , NAR, A , BAŞÇIL, N . "Kadınlarda metabolik sendromun alternatif prediktörleri". Pamukkale Tıp Dergisi 13 (2020 ): 341-349
RIS TY - JOUR T1 - Kadınlarda metabolik sendromun alternatif prediktörleri AU - Yusuf BOZKUŞ , Umut MOUSA , Nazlı GÜLSOY KİRNAP , Özlem TURHAN İYİDİR , Lala RAMAZANOVA , Aslı NAR , Neslihan BAŞÇIL TÜTÜNCÜ Y1 - 2020 PY - 2020 N1 - doi: 10.31362/patd.662692 DO - 10.31362/patd.662692 T2 - Pamukkale Tıp Dergisi JF - Journal JO - JOR SP - 341 EP - 349 VL - 13 IS - 2 SN - -1308-0865 M3 - doi: 10.31362/patd.662692 UR - https://doi.org/10.31362/patd.662692 Y2 - 2020 ER -
EndNote %0 Pamukkale Tıp Dergisi Kadınlarda metabolik sendromun alternatif prediktörleri %A Yusuf BOZKUŞ , Umut MOUSA , Nazlı GÜLSOY KİRNAP , Özlem TURHAN İYİDİR , Lala RAMAZANOVA , Aslı NAR , Neslihan BAŞÇIL TÜTÜNCÜ %T Kadınlarda metabolik sendromun alternatif prediktörleri %D 2020 %J Pamukkale Tıp Dergisi %P -1308-0865 %V 13 %N 2 %R doi: 10.31362/patd.662692 %U 10.31362/patd.662692
ISNAD BOZKUŞ, Yusuf , MOUSA, Umut , GÜLSOY KİRNAP, Nazlı , TURHAN İYİDİR, Özlem , RAMAZANOVA, Lala , NAR, Aslı , BAŞÇIL, Neslihan . "Kadınlarda metabolik sendromun alternatif prediktörleri". Pamukkale Tıp Dergisi 13 / 2 (Mayıs 2020): 341-349 . https://doi.org/10.31362/patd.662692
AMA BOZKUŞ Y , MOUSA U , GÜLSOY KİRNAP N , TURHAN İYİDİR Ö , RAMAZANOVA L , NAR A , BAŞÇIL N . Kadınlarda metabolik sendromun alternatif prediktörleri. Pamukkale Tıp Dergisi. 2020; 13(2): 341-349.
Vancouver BOZKUŞ Y , MOUSA U , GÜLSOY KİRNAP N , TURHAN İYİDİR Ö , RAMAZANOVA L , NAR A , BAŞÇIL N . Kadınlarda metabolik sendromun alternatif prediktörleri. Pamukkale Tıp Dergisi. 2020; 13(2): 349-341.