Tanısı FDG PET-BT İle Konan Erken Evre Takayasu Arteriti Olgusu Ve Literatürün Gözden Geçirilmesi

Yıl 2020, Cilt: 13 Sayı: 2, 425 - 429, 14.05.2020

Nagehan Didem Sarı , Gülşen Yörük , Gülhan Eren

https://doi.org/10.31362/patd.664272

Öz

Tanısı FDG PET-BT İle Konan Erken Evre Takayasu Arteriti Olgusu Ve Literatürün Gözden Geçirilmesi
Nagehan Didem Sarı, Gülşen Yörük, Gülhan Eren
Sağlık Bilimleri Üniversitesi İstanbul Eğitim ve Araştırma Hastanesi Enfeksiyon Hastalıkları ve klinik mikrobiyoloji Kliniği
Takayasu arteriti (TA), etyopatogenezi tam olarak bilinmeyen ve damar duvarında granulomatöz inflamasyonla seyreden, kronik seyirli büyük damar vaskülitidir. Klinik belirtiler hastalığın erken evrelerinde nonspesifik olmakla birlikte ilerleyen dönemde etkilenen damarların beslediği bölgelerde vasküler yetmezlik bulgularıyla seyreder. Hastalık Sebebi Bilinmeyen Ateş (SBA) kliniğiyle nadiren bulgu verebilir. Bu çalışmada SBA tetkiki esnasında tanısı FDG PET-CT ile konan erken evre TA olgusu sunulmuştur.
Anahtar Kelimeler: Sebebi bilinmeyen ateş, Takayasu arteriti, vaskülit
Türkçe Kısa Başlık: PET-BT İle Tanı Konan Takayasu Arteriti



An Early Stage Takayasu Arteritis Case Diagnosed with FDG PET-CT and Review of the Literature
Nagehan Didem Sarı, Gülşen Yörük, Gülhan Eren
Health Sciences University Istanbul Training and Research Hospital Infectious Diseases and Clinical Microbiology Clinic
Takayasu’s arteritis also known as pulseless disease is a kind of granulomatous vasculitis that characterized large size vessels involvement. It is usually occurs in female gender in young ages. At early stage of disease, nonspesific and different clinical presentation can occur.
At diagnosis, ischemic symptom are usually present in the affected vessels.
However, fever of unknown origin (FUO) is rare as an initial presentation and explanation the condition too difficult to diagnose.
In this case report, a patient who presented with a fever of unknown origin, described.
A 59-year-old female was diagnosed with Takayasu arteritis after fluorodeoxyglucose (FDG) positron-emission tomography-computed tomography (PET-CT) was performed at the early stage.
Keywords: Fever of unknown origin, PET-CT, Takayasu arteritis, Vasculitis
İngilizce Kısa Başlık: Takayasu arteritis diagnosed by PET-CT

Anahtar Kelimeler

Sebebi bilinmeyen ateş, Takayasu arteriti

Kaynakça

• 1. Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol 2002;55:481-6.
• 2. Takayasu M. Case with unusual changes of the central vessels in the retina. Acta Soc Ophtal Jpn. 1908;12:554–7. 3
• 3. Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu’s arteritis: a 2011 update. Auto¬immun Rev 2011;11:61-7.
• 4. Maksimowicz-McKinnon K, Clark TM, Hoffmann GS. Limitations of therapy and a guarded prognosis in an American cohort of Takayasu Arteritis patients. Arthritis Rheum. 2007;56:1000–7.
• 5. Emoke Stenová E, Mistecs S, Povinec P. FDG-PET/CT in large-vessel vasculitis: itsdiagnostic and follow up role. Rheumatol Int. 2010;3:1111–4.
• 6.Saritas F, Donmez S, Direskeneli H, Pamuk ON. The epidemiology of Takayasu arteritis: a hospital-based study from northwestern part of Turkey. Rheumatol Int 2016;36(7):911-6.
• 7. Bertaga F, Bosio G, Caobelli F, Motta F, Biasiotto G, Giubbini R. Role of 18F-fluorodeoxyglucose positron emission tomography/computed for therapy evaluation of patients with large vessel vasculitis. Jpn J Radiol. 2010;28: 199–204
• 8. Ilse J.E. Kouijzer, Catharina M. Mulders, Chantal P. Bleeker, and Wim J.G.F ever of Unknown Origin: the Value of FDG-PET/CT.Semin Nucl Med 48:100–107 © 2017 The Author(s). Published by Elsevier Inc. (http://creativecommons.org/licenses/by-nc-nd/4.0/)
• 9. Meller J, Strutz F, Siefker U, Scheel A, Sahlmann CO, Leh¬mann K, Conrad M, Vosshenrich R. Early diagnosis and follow-up of aortitis with [18F]FDG PET and MRI. Eur J Nucl Med Mol Imaging 2003;30:730-6.
• 10. Walter MA, Melzer RA, Schindler C, Müller-Brand J, Tyndall A, Nitzsche EU. The value of [ 18F]FDG-PET in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease. Eur J Nucl Med Mol Imaging. 2005;32:674–81.
• 11. Arend WP, Michel BA, Bloch DA, et al. The American Col¬lege of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum. 1990;33:1129-1134.
• 12. Schmidt WA, Nerenheim A, Seipelt E, et al. Diagnosis of early Takayasu arteritis with sonography. Rheumatology (Oxford). 2002;41:496-502.
• 13.Pacheco Castellanos MC, et al. Diagnóstico precoz de las vasculitis de grandes vasos. Utilidad de la tomografía por emisión de positrones con la tomografía axial computarizada. Reumatol Clin. 2013;9:65–68.
• 14. Oh MD, Ko EM, Suh C, Choi SJ, Choe KW. Fever of unde¬termined origin (FUO) as a presenting symptom of Takayasu arteritis. J Korean Med Assoc 1986;29:1018-22.
• 15. Joohae Kim, and Myoung-don Oh .FDG PET-CT in the Diagnosis of Takayasu Arteritis Presenting as Fever of Unknown Origin: A Case Report . Infect Chemother 2015;47(3):190-193.
• 16.M. Bicakcigil, K. Aksu, S. Kamali,. Takayasu's arteritis in Turkey - Clinical and angiographic features of 248 patient Clin Exp Rheumatol. 2009 Jan-Feb;27(1 Suppl 52):S59-64