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Yoğun bakımda Covid-19

Yıl 2020, Cilt: 13 Sayı: 3, 833 - 841, 18.09.2020
https://doi.org/10.31362/patd.740256

Öz

Koronavirüsler 21.yüzyılda üç kez ciddi salgınlara yol açmıştır. Yeni tanımlanan SARS-CoV-2 virüsünün neden olduğu pandemi küresel endişeye neden olmuştur. Hastalığının hızlı yayılması, geniş kitleleri etkilemesi, yüksek oranda hastane ve yoğun bakım yatışı gerektirmesi nedeniyle bu pandemide yoğun bakımların yönetimi ve yoğun bakımda hasta takibi ciddi bir önem arz etmiştir. Bu derlemede COVİD-19 tanılı yoğun bakım hastalarının tedavileri şu ana dek elde edilen literatürler ve deneyimler ışığında derlenmiştir.

Kaynakça

  • 1. https://www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/ .Erişim 1 Mayıs 2020.
  • 2. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/. Erişim 1 Mayıs 2020.
  • 3. https://covid19.who.int/ . Erişim 6 mayıs 2020.
  • 4. https://covid19bilgi.saglik.gov.tr/tr/ . Erişim 6 Mayıs 2020.
  • 5. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease. 2019.
  • 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497-506.
  • 7. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. Jama. 2020;323(11):1061-9.
  • 8. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020;395(10223):507-13.
  • 9. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020.
  • 10. Mission W-CJ. Report of the who-china joint mission on coronavirus disease 2019 (covid-19). World Health Organization) Retrieved. 2020;8.
  • 11. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020.
  • 12. Yang X, Yu Y, Xu J, Shu H, Liu H, Wu Y, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020.
  • 13. Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State. Jama. 2020.
  • 14. https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf . Erişim 1 Mayıs 2020.
  • 15. Phua J, Weng L, Ling L, Egi M, Lim C-M, Divatia JV, et al. Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. The Lancet Respiratory Medicine. 2020.
  • 16. Cook T, El‐Boghdadly K, McGuire B, McNarry A, Patel A, Higgs A. Consensus guidelines for managing the airway in patients with COVID‐19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists. Anaesthesia. 2020.
  • 17. Yao W, Wang T, Jiang B, Gao F, Wang L, Zheng H, et al. Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations. British Journal of Anaesthesia. 2020.
  • 18. Wax RS, Christian MD. Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients. Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 2020:1-9.
  • 19. Kearsley R. Consensus guidelines for managing the airway in patients with COVID‐19. Anaesthesia. 2020.
  • 20. Everington K. Taiwanese doctor invents device to protect US doctors against coronavirus. Taiwan News. 2020.
  • 21. Canelli R, Connor CW, Gonzalez M, Nozari A, Ortega R. Barrier enclosure during endotracheal intubation. New England Journal of Medicine. 2020.
  • 22. Carrillo A, Gonzalez-Diaz G, Ferrer M, Martinez-Quintana ME, Lopez-Martinez A, Llamas N, et al. Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Intensive care medicine. 2012;38(3):458-66.
  • 23. Rochwerg B, Brochard L, Elliott MW, Hess D, Hill NS, Nava S, et al. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. European Respiratory Journal. 2017;50(2):1602426.
  • 24. Cheung TM, Yam LY, So LK, Lau AC, Poon E, Kong BM, et al. Effectiveness of noninvasive positive pressure ventilation in the treatment of acute respiratory failure in severe acute respiratory syndrome. Chest. 2004;126(3):845-50.
  • 25. Ñamendys-Silva SA. Respiratory support for patients with COVID-19 infection. The Lancet Respiratory Medicine. 2020;8(4):e18.
  • 26. Meng L, Qiu H, Wan L, Ai Y, Xue Z, Guo Q, et al. Intubation and Ventilation amid the COVID-19 OutbreakWuhan’s Experience. Anesthesiology: The Journal of the American Society of Anesthesiologists. 2020.
  • 27. Arabi YM, Fowler R, Hayden FG. Critical care management of adults with community-acquired severe respiratory viral infection. Intensive care medicine. 2020;46(2):315-28.
  • 28. Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, et al. Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19). Intensive Care Medicine. 2020:1-34.
  • 29. Rochwerg B, Granton D, Wang D, Helviz Y, Einav S, Frat J-P, et al. High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis. Intensive care medicine. 2019;45(5):563-72.
  • 30. Koga Y, Kaneda K, Fujii N, Tanaka R, Miyauchi T, Fujita M, et al. Comparison of high‐flow nasal cannula oxygen therapy and non‐invasive ventilation as first‐line therapy in respiratory failure: a multicenter retrospective study. Acute Medicine & Surgery. 2019.
  • 31. Matthay MA, Aldrich JM, Gotts JE. Treatment for severe acute respiratory distress syndrome from COVID-19. The Lancet Respiratory Medicine. 2020.
  • 32. Li L, Li R, Wu Z, Yang X, Zhao M, Liu J, et al. Therapeutic strategies for critically ill patients with COVID-19. Annals of Intensive Care. 2020;10(1):1-9.
  • 33. Marini JJ, Gattinoni L. Management of COVID-19 Respiratory Distress. JAMA. 2020.
  • 34. MacLaren G, Fisher D, Brodie D. Preparing for the most critically ill patients with COVID-19: the potential role of extracorporeal membrane oxygenation. Jama. 2020;323(13):1245-6.
  • 35. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). Jama. 2016;315(8):801-10.
  • 36. Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. COVID-19: consider cytokine storm syndromes and immunosuppression. The Lancet. 2020;395(10229):1033-4.
  • 37. Fu B, Xu X, Wei H. Why tocilizumab could be an effective treatment for severe COVID-19? Journal of Translational Medicine. 2020;18(1):1-5.
  • 38. Moore B, June CH. Cytokine release syndrome in severe COVID-19. Science (New York, NY). 2020.
  • 39. Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, et al. Kidney impairment is associated with in-hospital death of COVID-19 patients. MedRxiv. 2020.
  • 40. Zhou M, Zhang X, Qu J. Coronavirus disease 2019 (COVID-19): a clinical update. Frontiers of medicine. 2020:1-10.
  • 41. Durvasula R, Wellington T, McNamara E, Watnick S. COVID-19 and Kidney Failure in the Acute Care Setting: Our Experience From Seattle. American Journal of Kidney Diseases. 2020.
  • 42. Ronco C, Reis T. Kidney involvement in COVID-19 and rationale for extracorporeal therapies. Nature Reviews Nephrology. 2020:1-3.
  • 43. Santoso A, Pranata R, Wibowo A, Al-Farabi MJ, Huang I, Antariksa B. Cardiac injury is associated with mortality and critically ill pneumonia in COVID-19: A meta-analysis. The American Journal of Emergency Medicine. 2020.
  • 44. Guzik TJ, Mohiddin SA, Dimarco A, Patel V, Savvatis K, Marelli-Berg FM, et al. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res. 2020.
  • 45. Testa S, Prandoni P, Paoletti O, Morandini R, Tala M, Dellanoce C, et al. Direct oral anticoagulant plasma levels striking increase in severe COVID‐19 respiratory syndrome patients treated with antiviral agents. The Cremona experience. Journal of Thrombosis and Haemostasis. 2020.
  • 46. Thachil J, Tang N, Gando S, Falanga A, Cattaneo M, Levi M, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19. Journal of Thrombosis and Haemostasis. 2020.
  • 47. https://erc.edu/ .Erişim 1 Mayıs 2020.
  • 48. Mahase E. Coronavirus: covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate. British Medical Journal Publishing Group; 2020.
  • 49. Zheng Z, Peng F, Xu B, Zhao J, Liu H, Peng J, et al. Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis. Journal of Infection. 2020.
  • 50. Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive care medicine. 2020:1-3.
  • 51. https://bestpractice.bmj.com/topics/en-gb/3000168/prognosis .Erişim 6 mayıs 2020.

Covid-19 in intensive care unit

Yıl 2020, Cilt: 13 Sayı: 3, 833 - 841, 18.09.2020
https://doi.org/10.31362/patd.740256

Öz

Abstract
Coronaviruses have caused serious outbreaks three times in the 21st century. The pandemic caused by the
newly identified SARS-CoV-2 virus has caused global concern. In this pandemic, the management of intensive
care units and patient follow-up in intensive care are of great importance due to the rapid spread of the disease,
affecting large masses, and more hospital and intensive care. In this review, the treatment of intensive care
patients diagnosed with COVID-19 has been collected in the light of the literature and experience obtained so
far.

Kaynakça

  • 1. https://www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/ .Erişim 1 Mayıs 2020.
  • 2. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/. Erişim 1 Mayıs 2020.
  • 3. https://covid19.who.int/ . Erişim 6 mayıs 2020.
  • 4. https://covid19bilgi.saglik.gov.tr/tr/ . Erişim 6 Mayıs 2020.
  • 5. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease. 2019.
  • 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497-506.
  • 7. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. Jama. 2020;323(11):1061-9.
  • 8. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020;395(10223):507-13.
  • 9. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020.
  • 10. Mission W-CJ. Report of the who-china joint mission on coronavirus disease 2019 (covid-19). World Health Organization) Retrieved. 2020;8.
  • 11. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020.
  • 12. Yang X, Yu Y, Xu J, Shu H, Liu H, Wu Y, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020.
  • 13. Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State. Jama. 2020.
  • 14. https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf . Erişim 1 Mayıs 2020.
  • 15. Phua J, Weng L, Ling L, Egi M, Lim C-M, Divatia JV, et al. Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. The Lancet Respiratory Medicine. 2020.
  • 16. Cook T, El‐Boghdadly K, McGuire B, McNarry A, Patel A, Higgs A. Consensus guidelines for managing the airway in patients with COVID‐19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists. Anaesthesia. 2020.
  • 17. Yao W, Wang T, Jiang B, Gao F, Wang L, Zheng H, et al. Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations. British Journal of Anaesthesia. 2020.
  • 18. Wax RS, Christian MD. Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients. Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 2020:1-9.
  • 19. Kearsley R. Consensus guidelines for managing the airway in patients with COVID‐19. Anaesthesia. 2020.
  • 20. Everington K. Taiwanese doctor invents device to protect US doctors against coronavirus. Taiwan News. 2020.
  • 21. Canelli R, Connor CW, Gonzalez M, Nozari A, Ortega R. Barrier enclosure during endotracheal intubation. New England Journal of Medicine. 2020.
  • 22. Carrillo A, Gonzalez-Diaz G, Ferrer M, Martinez-Quintana ME, Lopez-Martinez A, Llamas N, et al. Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Intensive care medicine. 2012;38(3):458-66.
  • 23. Rochwerg B, Brochard L, Elliott MW, Hess D, Hill NS, Nava S, et al. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. European Respiratory Journal. 2017;50(2):1602426.
  • 24. Cheung TM, Yam LY, So LK, Lau AC, Poon E, Kong BM, et al. Effectiveness of noninvasive positive pressure ventilation in the treatment of acute respiratory failure in severe acute respiratory syndrome. Chest. 2004;126(3):845-50.
  • 25. Ñamendys-Silva SA. Respiratory support for patients with COVID-19 infection. The Lancet Respiratory Medicine. 2020;8(4):e18.
  • 26. Meng L, Qiu H, Wan L, Ai Y, Xue Z, Guo Q, et al. Intubation and Ventilation amid the COVID-19 OutbreakWuhan’s Experience. Anesthesiology: The Journal of the American Society of Anesthesiologists. 2020.
  • 27. Arabi YM, Fowler R, Hayden FG. Critical care management of adults with community-acquired severe respiratory viral infection. Intensive care medicine. 2020;46(2):315-28.
  • 28. Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, et al. Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19). Intensive Care Medicine. 2020:1-34.
  • 29. Rochwerg B, Granton D, Wang D, Helviz Y, Einav S, Frat J-P, et al. High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis. Intensive care medicine. 2019;45(5):563-72.
  • 30. Koga Y, Kaneda K, Fujii N, Tanaka R, Miyauchi T, Fujita M, et al. Comparison of high‐flow nasal cannula oxygen therapy and non‐invasive ventilation as first‐line therapy in respiratory failure: a multicenter retrospective study. Acute Medicine & Surgery. 2019.
  • 31. Matthay MA, Aldrich JM, Gotts JE. Treatment for severe acute respiratory distress syndrome from COVID-19. The Lancet Respiratory Medicine. 2020.
  • 32. Li L, Li R, Wu Z, Yang X, Zhao M, Liu J, et al. Therapeutic strategies for critically ill patients with COVID-19. Annals of Intensive Care. 2020;10(1):1-9.
  • 33. Marini JJ, Gattinoni L. Management of COVID-19 Respiratory Distress. JAMA. 2020.
  • 34. MacLaren G, Fisher D, Brodie D. Preparing for the most critically ill patients with COVID-19: the potential role of extracorporeal membrane oxygenation. Jama. 2020;323(13):1245-6.
  • 35. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). Jama. 2016;315(8):801-10.
  • 36. Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. COVID-19: consider cytokine storm syndromes and immunosuppression. The Lancet. 2020;395(10229):1033-4.
  • 37. Fu B, Xu X, Wei H. Why tocilizumab could be an effective treatment for severe COVID-19? Journal of Translational Medicine. 2020;18(1):1-5.
  • 38. Moore B, June CH. Cytokine release syndrome in severe COVID-19. Science (New York, NY). 2020.
  • 39. Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, et al. Kidney impairment is associated with in-hospital death of COVID-19 patients. MedRxiv. 2020.
  • 40. Zhou M, Zhang X, Qu J. Coronavirus disease 2019 (COVID-19): a clinical update. Frontiers of medicine. 2020:1-10.
  • 41. Durvasula R, Wellington T, McNamara E, Watnick S. COVID-19 and Kidney Failure in the Acute Care Setting: Our Experience From Seattle. American Journal of Kidney Diseases. 2020.
  • 42. Ronco C, Reis T. Kidney involvement in COVID-19 and rationale for extracorporeal therapies. Nature Reviews Nephrology. 2020:1-3.
  • 43. Santoso A, Pranata R, Wibowo A, Al-Farabi MJ, Huang I, Antariksa B. Cardiac injury is associated with mortality and critically ill pneumonia in COVID-19: A meta-analysis. The American Journal of Emergency Medicine. 2020.
  • 44. Guzik TJ, Mohiddin SA, Dimarco A, Patel V, Savvatis K, Marelli-Berg FM, et al. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res. 2020.
  • 45. Testa S, Prandoni P, Paoletti O, Morandini R, Tala M, Dellanoce C, et al. Direct oral anticoagulant plasma levels striking increase in severe COVID‐19 respiratory syndrome patients treated with antiviral agents. The Cremona experience. Journal of Thrombosis and Haemostasis. 2020.
  • 46. Thachil J, Tang N, Gando S, Falanga A, Cattaneo M, Levi M, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19. Journal of Thrombosis and Haemostasis. 2020.
  • 47. https://erc.edu/ .Erişim 1 Mayıs 2020.
  • 48. Mahase E. Coronavirus: covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate. British Medical Journal Publishing Group; 2020.
  • 49. Zheng Z, Peng F, Xu B, Zhao J, Liu H, Peng J, et al. Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis. Journal of Infection. 2020.
  • 50. Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive care medicine. 2020:1-3.
  • 51. https://bestpractice.bmj.com/topics/en-gb/3000168/prognosis .Erişim 6 mayıs 2020.
Toplam 51 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Anesteziyoloji
Bölüm Derleme
Yazarlar

Ülkü Arslan Bu kişi benim 0000-0001-5277-9034

Cansu Ozgen Bu kişi benim 0000-0003-2376-0419

Hülya Sungurtekin 0000-0002-9453-5625

Yayımlanma Tarihi 18 Eylül 2020
Gönderilme Tarihi 20 Mayıs 2020
Kabul Tarihi 22 Mayıs 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 13 Sayı: 3

Kaynak Göster

APA Arslan, Ü., Ozgen, C., & Sungurtekin, H. (2020). Yoğun bakımda Covid-19. Pamukkale Medical Journal, 13(3), 833-841. https://doi.org/10.31362/patd.740256
AMA Arslan Ü, Ozgen C, Sungurtekin H. Yoğun bakımda Covid-19. Pam Tıp Derg. Eylül 2020;13(3):833-841. doi:10.31362/patd.740256
Chicago Arslan, Ülkü, Cansu Ozgen, ve Hülya Sungurtekin. “Yoğun bakımda Covid-19”. Pamukkale Medical Journal 13, sy. 3 (Eylül 2020): 833-41. https://doi.org/10.31362/patd.740256.
EndNote Arslan Ü, Ozgen C, Sungurtekin H (01 Eylül 2020) Yoğun bakımda Covid-19. Pamukkale Medical Journal 13 3 833–841.
IEEE Ü. Arslan, C. Ozgen, ve H. Sungurtekin, “Yoğun bakımda Covid-19”, Pam Tıp Derg, c. 13, sy. 3, ss. 833–841, 2020, doi: 10.31362/patd.740256.
ISNAD Arslan, Ülkü vd. “Yoğun bakımda Covid-19”. Pamukkale Medical Journal 13/3 (Eylül 2020), 833-841. https://doi.org/10.31362/patd.740256.
JAMA Arslan Ü, Ozgen C, Sungurtekin H. Yoğun bakımda Covid-19. Pam Tıp Derg. 2020;13:833–841.
MLA Arslan, Ülkü vd. “Yoğun bakımda Covid-19”. Pamukkale Medical Journal, c. 13, sy. 3, 2020, ss. 833-41, doi:10.31362/patd.740256.
Vancouver Arslan Ü, Ozgen C, Sungurtekin H. Yoğun bakımda Covid-19. Pam Tıp Derg. 2020;13(3):833-41.
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