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İntraosseöz migrasyonlu kalsifik tendinitin radyolojik değerlendirmesi: tek merkez deneyimi

Yıl 2025, Cilt: 18 Sayı: 3, 8 - 8

Öz

Amaç: Kalsiyum depositlerin kemik, kaslar ve subakromiyal-subdeltoid bursa gibi komşu dokulara göçü, tanısal zorluklara ve gereksiz prosedürlere yol açabilen nadir bir komplikasyondur. Bu çalışmanın amacı, rotator manşet kalsifik tendinitinin nadir görülen intraosseöz migrasyonunu tanımlamak ve bu vakaları demografik özellikler, ilişkili patolojiler ve radyolojik bulgular açısından değerlendirmektir.
Gereç ve yöntem: Bu retrospektif çalışma, Ocak 2021 ile Eylül 2024 tarihleri arasında gerçekleştirilmiş ve 3,755 omuz MRG incelemesi gözden geçirilmiştir. Hariç tutulanlar arasında hareket artefaktı olan hastalar, pediatrik vakalar, travma veya cerrahi öyküsü olanlar ve enfeksiyon vakaları yer almıştır. İki radyolog kalsifik tendinit ve intraosseöz migrasyon vakalarını bağımsız olarak değerlendirmiş, bulgular demografik veriler ve ilişkili patolojilerle analiz edilmiştir.
Bulgular: 3,000 tarama sonucunda vakaların %8,17'sinde kalsifik tendinit tespit edilmiştir. İntraosseöz komplikasyonlar toplam popülasyonun %0,5’inde ve kalsifik tendinit vakalarının %6,12'sinde gözlenmiştir. Kalsifik tendinit hastalarının çoğunluğu (%73,77) kadın olup, intraosseöz komplikasyonların %86,67’si kadın hastalarda görülmüştür (p=0.211 (Fisher's Exact Test)). İntraosseöz komplikasyonlar, supraspinatus ve infraspinatus tendonlarının daha yüksek tutulma oranlarıyla ilişkilendirilmiştir (%73'er), komplikasyonu olmayan hastalarda ise bu oranlar sırasıyla %63 ve %36 olarak gözlenmiştir (p<0.001).
Sonuç: Kalsifik tendinit, nadir görülen intraosseöz uzanımlar gösterebilir ve doğru tanı için dikkatli görüntüleme gerektirir. MRG ve BT, bu vakaların tanısında kritik bir rol oynar. Tedavi edilmeyen vakalarda komplikasyonlar devam ederken, ultrason rehberliğinde yapılan enjeksiyon tedavisi etkili sonuçlar vermektedir. Kalsifik tendinit, görüntülemede tümörleri taklit edebileceğinden doğru ayırıcı tanı gereklidir. İntraosseöz komplikasyonların erken teşhisi ve uygun tedavisi esastır. Gelecekteki çalışmalar, daha geniş popülasyonlar ve uzun dönem takiplerle prognoz ve tedavi sonuçlarını daha iyi değerlendirmelidir.

Etik Beyan

Etik kurul onayı: Dicle Üniversitesi Tıp Etiği Kurulu'ndan (25.09.2025/243) etik kurul onayı alındı.

Kaynakça

  • 1. Paruthikunnan SM, Boily M, Martin MH, Assaf A, Jaffer R. Intra-osseous migration in calcific rotator cuff tendinopathy- a novel depiction of temporal evolution on multimodality imaging. BJR Case Rep. 2022;8(2):20210156. Published 2022 Jan 20. doi:10.1259/bjrcr.20210156
  • 2. Marinetti A, Sessa M, Falzone A, Della Sala SW. Intraosseous migration of tendinous calcifications: two case reports. Skeletal Radiol. 2018;47(1):131-136. doi:10.1007/s00256-017-2769-4 3. Kalaycı CB, Kızılkaya E. Calcific tendinitis: intramuscular and intraosseous migration. Diagn Interv Radiol. 2019;25(6):480-484. doi:10.5152/dir.2019.18593
  • 4. Malghem J, Omoumi P, Lecouvet F, Vande Berg B. Intraosseous migration of tendinous calcifications: cortical erosions, subcortical migration and extensive intramedullary diffusion, a SIMS series. Skeletal Radiol. 2015;44(10):1403-1412. doi:10.1007/s00256-015-2165-x
  • 5. Flemming DJ, Murphey MD, Shekitka KM, Temple HT, Jelinek JJ, Kransdorf MJ. Osseous involvement in calcific tendinitis: a retrospective review of 50 cases. AJR Am J Roentgenol. 2003;181(4):965-972. doi:10.2214/ajr.181.4.1810965
  • 6. Martin S, Rapariz JM. Intraosseous calcium migration in calcifying tendinitis: a rare cause of single sclerotic injury in the humeral head (2010: 2b). Eur Radiol. 2010;20(5):1284-1286. doi:10.1007/s00330-009-1500-9
  • 7. Chan R, Kim DH, Millett PJ, Weissman BN. Calcifying tendinitis of the rotator cuff with cortical bone erosion [published correction appears in Skeletal Radiol. 2005 Jan;34(1):61]. Skeletal Radiol. 2004;33(10):596-599. doi:10.1007/s00256-004-0770-1
  • 8. Zampa V, Aringhieri G, Rossi P, Capanna R, Caramella D. Humeral greater tuberosity osteolysis as a complication of intraosseous calcification migration: natural history depicted by imaging. Acta Biomed. 2021;92(S1):e2021052. Published 2021 Apr 30. doi:10.23750/abm.v92iS1.8370
  • 9. Angileri HS, Gohal C, Comeau-Gauthier M, et al. Chronic calcific tendonitis of the rotator cuff: a systematic review and meta-analysis of randomized controlled trials comparing operative and nonoperative interventions. J Shoulder Elbow Surg. 2023;32(8):1746-1760. doi:10.1016/j.jse.2023.03.017
  • 10. DE Carli A, Pulcinelli F, Rose GD, Pitino D, Ferretti A. Calcific tendinitis of the shoulder. Joints. 2014;2(3):130-136. Published 2014 Aug 1. doi:10.11138/jts/2014.2.3.130
  • 11. Merolla G, Bhat MG, Paladini P, Porcellini G. Complications of calcific tendinitis of the shoulder: a concise review. J Orthop Traumatol. 2015;16(3):175-183. doi:10.1007/s10195-015-0339-x
  • 12. Klontzas ME, Vassalou EE, Karantanas AH. Calcific tendinopathy of the shoulder with intraosseous extension: outcomes of ultrasound-guided percutaneous irrigation. Skeletal Radiol. 2017;46(2):201-208. doi:10.1007/s00256-016-2538-9
  • 13. Sussmann AR, Cohen J, Nomikos GC, Schweitzer ME. Magnetic resonance imaging of shoulder arthropathies. Magn Reson Imaging Clin N Am. 2012;20(2):349-xii. doi:10.1016/j.mric.2012.01.004
  • 14. Lanza E, Banfi G, Serafini G, et al. Ultrasound-guided percutaneous irrigation in rotator cuff calcific tendinopathy: what is the evidence? A systematic review with proposals for future reporting. Eur Radiol. 2015;25(7):2176-2183. doi:10.1007/s00330-014-3567-1
  • 15. Kim YS, Lee HM, Kim JP. Acute calcific tendinitis of the rectus femoris associated with intraosseous involvement: a case report with serial CT and MRI findings. Eur J Orthop Surg Traumatol. 2013;23 Suppl 2:S233-S239. doi:10.1007/s00590-012-1156-z
  • 16. Porcellini G, Paladini P, Campi F, Pegreffi F. Osteolytic lesion of greater tuberosity in calcific tendinitis of the shoulder. J Shoulder Elbow Surg. 2009;18(2):210-215. doi:10.1016/j.jse.2008.09.016

Radiological evaluation of calcific tendinitis with ıntraosseous migration: a single-center experience

Yıl 2025, Cilt: 18 Sayı: 3, 8 - 8

Öz

Purpose: Migration of calcific deposits into adjacent tissues, such as bones, muscles, and the subacromial-subdeltoid bursa, is a rare complication that can lead to diagnostic challenges and unnecessary procedures. This study aims to describe the uncommon intraosseous migration of rotator cuff calcific tendinitis and evaluate these cases concerning demographic characteristics, associated pathologies, and radiological findings.
Materials and methods: This retrospective study, conducted between January 2021 and September 2024, reviewed 3.755 shoulder MRI scans. Exclusions included motion artifacts, pediatric cases, trauma or surgery history, and infections. Two radiologists independently evaluated cases of calcific tendinitis and intraosseous migration, analyzing findings against demographic data and related pathologies.
Results: Out of 3.000 scans, calcific tendinitis was found in 8.17% of cases. Intraosseous complications occurred in 0.5% of the total population and 6.12% of tendinitis cases. Most calcific tendinitis patients (73.77%) were female, with 86.67% of intraosseous cases being women (p=0.211 (Fisher's Exact Test)). The supraspinatus tendon was most frequently affected (63% of cases), with effusion being the most common pathology (55%). Intraosseous complications showed higher involvement of the supraspinatus and infraspinatus tendons (73% each) compared to patients without complications (63% and 36%, p<0.001).
Conclusion: Calcific tendinitis can present rare intraosseous extensions, requiring careful imaging for accurate diagnosis. MRI and CT play crucial roles in identifying these cases. Untreated cases show persistent complications, while ultrasound-guided injections provide effective treatment. Proper differential diagnosis is necessary as calcific tendinitis may mimic tumors. Early diagnosis and appropriate treatment of intraosseous complications are essential. Future studies should explore larger populations and long-term follow-up for better evaluation of prognosis and outcomes.

Etik Beyan

Ethics committee approval: Ethics Committee approval from Dicle University Medical Ethics Committee (09.25.2025/243)) were obtained.

Kaynakça

  • 1. Paruthikunnan SM, Boily M, Martin MH, Assaf A, Jaffer R. Intra-osseous migration in calcific rotator cuff tendinopathy- a novel depiction of temporal evolution on multimodality imaging. BJR Case Rep. 2022;8(2):20210156. Published 2022 Jan 20. doi:10.1259/bjrcr.20210156
  • 2. Marinetti A, Sessa M, Falzone A, Della Sala SW. Intraosseous migration of tendinous calcifications: two case reports. Skeletal Radiol. 2018;47(1):131-136. doi:10.1007/s00256-017-2769-4 3. Kalaycı CB, Kızılkaya E. Calcific tendinitis: intramuscular and intraosseous migration. Diagn Interv Radiol. 2019;25(6):480-484. doi:10.5152/dir.2019.18593
  • 4. Malghem J, Omoumi P, Lecouvet F, Vande Berg B. Intraosseous migration of tendinous calcifications: cortical erosions, subcortical migration and extensive intramedullary diffusion, a SIMS series. Skeletal Radiol. 2015;44(10):1403-1412. doi:10.1007/s00256-015-2165-x
  • 5. Flemming DJ, Murphey MD, Shekitka KM, Temple HT, Jelinek JJ, Kransdorf MJ. Osseous involvement in calcific tendinitis: a retrospective review of 50 cases. AJR Am J Roentgenol. 2003;181(4):965-972. doi:10.2214/ajr.181.4.1810965
  • 6. Martin S, Rapariz JM. Intraosseous calcium migration in calcifying tendinitis: a rare cause of single sclerotic injury in the humeral head (2010: 2b). Eur Radiol. 2010;20(5):1284-1286. doi:10.1007/s00330-009-1500-9
  • 7. Chan R, Kim DH, Millett PJ, Weissman BN. Calcifying tendinitis of the rotator cuff with cortical bone erosion [published correction appears in Skeletal Radiol. 2005 Jan;34(1):61]. Skeletal Radiol. 2004;33(10):596-599. doi:10.1007/s00256-004-0770-1
  • 8. Zampa V, Aringhieri G, Rossi P, Capanna R, Caramella D. Humeral greater tuberosity osteolysis as a complication of intraosseous calcification migration: natural history depicted by imaging. Acta Biomed. 2021;92(S1):e2021052. Published 2021 Apr 30. doi:10.23750/abm.v92iS1.8370
  • 9. Angileri HS, Gohal C, Comeau-Gauthier M, et al. Chronic calcific tendonitis of the rotator cuff: a systematic review and meta-analysis of randomized controlled trials comparing operative and nonoperative interventions. J Shoulder Elbow Surg. 2023;32(8):1746-1760. doi:10.1016/j.jse.2023.03.017
  • 10. DE Carli A, Pulcinelli F, Rose GD, Pitino D, Ferretti A. Calcific tendinitis of the shoulder. Joints. 2014;2(3):130-136. Published 2014 Aug 1. doi:10.11138/jts/2014.2.3.130
  • 11. Merolla G, Bhat MG, Paladini P, Porcellini G. Complications of calcific tendinitis of the shoulder: a concise review. J Orthop Traumatol. 2015;16(3):175-183. doi:10.1007/s10195-015-0339-x
  • 12. Klontzas ME, Vassalou EE, Karantanas AH. Calcific tendinopathy of the shoulder with intraosseous extension: outcomes of ultrasound-guided percutaneous irrigation. Skeletal Radiol. 2017;46(2):201-208. doi:10.1007/s00256-016-2538-9
  • 13. Sussmann AR, Cohen J, Nomikos GC, Schweitzer ME. Magnetic resonance imaging of shoulder arthropathies. Magn Reson Imaging Clin N Am. 2012;20(2):349-xii. doi:10.1016/j.mric.2012.01.004
  • 14. Lanza E, Banfi G, Serafini G, et al. Ultrasound-guided percutaneous irrigation in rotator cuff calcific tendinopathy: what is the evidence? A systematic review with proposals for future reporting. Eur Radiol. 2015;25(7):2176-2183. doi:10.1007/s00330-014-3567-1
  • 15. Kim YS, Lee HM, Kim JP. Acute calcific tendinitis of the rectus femoris associated with intraosseous involvement: a case report with serial CT and MRI findings. Eur J Orthop Surg Traumatol. 2013;23 Suppl 2:S233-S239. doi:10.1007/s00590-012-1156-z
  • 16. Porcellini G, Paladini P, Campi F, Pegreffi F. Osteolytic lesion of greater tuberosity in calcific tendinitis of the shoulder. J Shoulder Elbow Surg. 2009;18(2):210-215. doi:10.1016/j.jse.2008.09.016
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Radyoloji ve Organ Görüntüleme
Bölüm Araştırma Makalesi
Yazarlar

Muhammed Tekinhatun 0000-0002-3240-6991

Kadirhan Alver 0000-0002-4692-2401

İbrahim Akbudak 0000-0001-9874-0055

Mehmet Turmak 0000-0002-2278-4729

Muhammed Akif Deniz 0000-0002-9586-2425

Erken Görünüm Tarihi 14 Ocak 2025
Yayımlanma Tarihi
Gönderilme Tarihi 4 Ekim 2024
Kabul Tarihi 2 Ocak 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 18 Sayı: 3

Kaynak Göster

AMA Tekinhatun M, Alver K, Akbudak İ, Turmak M, Deniz MA. Radiological evaluation of calcific tendinitis with ıntraosseous migration: a single-center experience. Pam Tıp Derg. Ocak 2025;18(3):8-8.
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