Stevens Johnson Sendromu Tanısı Alan Bir Çocuk Olgu

Yıl 2018, Cilt: 16 Sayı: 1, 115 - 124, 01.04.2018

Burcu Tahire Köksal , Özlem Yılmaz Özbek Esra Özmen Merih Tepeoğlu

Öz

Stevens-Johnson sendromu (SJS) nadir görülen fakat hayatı tehdit edebilen mukokutanöz tutulumun
olduğu T hücre aracılı bir aşırı duyarlılık reaksiyonudur. Olguların çoğu ilaçlarla tetiklenmektedir.
Enfeksiyonlar, aşılar, kimyasallar, sistemik ve malign hastalıklar da etiyolojide rol alabilir. Hastalık
genellikle ateş, halsizlik, başağrısı, miyalji, artralji ve üst solunum yolu enfeksiyonu gibi prodromal
semptomlarla başlar. Stevens-Johnson sendromu için özel bir tedavi yöntemi bulunmamaktadır.
Hastalık tanısının hızla konması, sebep olan ilacın erken dönemde kesilmesi ve destek tedavisi tedavinin
temelini oluşturmaktadır. Sistemik steroid, intravenöz immünglobulin (IVIG) ve siklosporin gibi ilaçlar
da tedavi amacıyla kullanılmaktadır.
Stevens-Johnson sendromu farkındalığını arttırmak, erken tanı ve destek tedavinin önemini vurgulamak
amacıyla SJS tanısı alan bir olgu sunulmuştur.

ABSTRACT
Stevens-Johnson syndrome (SJS) is a rare but life-threatening, mucocutaneous, T cell mediated
hypersensitivity reaction. Most of the cases are triggered by a drug. Infections, vaccines, chemicals,
systemic or malign diseases may have also roles in etiology. Disease generally starts with prodromal
symptoms including fever, malaise, headache, myalgia or upper respiratory tract infection. There is no
specific treatment modality for SJS.
Diagnosing the disease rapidly, discontinuation of the suspected drug immediately, and supportive
therapy are the main steps in treatment. Medications like systemic steroids, intravenous immunglobulin
(IVIG) and cyclosporin are also used in treatment.
Our aim in presenting a case of SJS is to increase awareness of this disease, to emphasize importance of
immediate diagnosis and supportive therapy.

Anahtar Kelimeler

Çocuk, IVIG, parasetamol, Stevens Johnson Sendromu

Kaynakça

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