Vitamin D Deficiency in Syrian and Iraqi Immigrant Children

Yıl 2020, Cilt: 18 Sayı: 1, 104 - 113, 15.04.2020

Eyüp Sarı

Öz

INTRODUCTION: Recent studies have suggested that vitamin D deficiency in immigrant children is widespread.The aim of this study was to establish the correlation between vitamin D levels, age, gender, diagnosis, and nationality of Syrian and Iraqi immigrant children with vitamin D deficiency.

MATERIALS and METHODS: Syrian and Iraqi immigrant children whose blood 25(OH)D levels were checked in hospitals in the province of Ankara in Turkey between the dates of 1 January 2015 and 31 December 2018. Vitamin levels of 25(OH)D were classified as <12 ng/mL deficiency, 12-20 ng/mL insufficiency, >20 ng/mL normal.

RESULTS: A total of 171 immigrant children with a mean age of 10.1±5.3 years were included in the study. Of these children, while 25.7% were observed to have normal (>20 ng/mL) 25(OH)D blood level, 31.2% were established to have mild deficiency (12-20ng/mL), and 40.9% were found to have vitamin D deficiency requiring treatment (<12ng/mL). When compared the vitamin D levels of children according to their gender, age groups, and nationalities, girls (p=0.003) and children at the age of 10 and above (p≤0.001) were observed to have lower 25(OH)D vitamin levels.

CONCLUSIONS: The high frequency of vitamin D deficiency in immigrant children (especially girls older than 10 years) indicates a need for supplementation and nutritional support

Anahtar Kelimeler

Immigrant Children, Vitamin D

Suriye Ve Iraklı Göçmen Çocuklarda D Vitamini Eksikliği

Öz

GİRİŞ ve AMAÇ: Son yıllarda yapılan çalışmalarda çocuklarda D vitamini eksikliğinin yaygın olarak gözlendiği özellikle de göçmenlerde bu oranın daha fazla olduğu bildirilmiştir. Biz de bu çalışmada Suriye ve Iraklı göçmen çocukların D vitamini düzeyleri ve yaş, cinsiyet, tanı ve uyruklarının D vitamini eksikliğiyle ilişkilerini belirlemeyi amaçladık.

YÖNTEM ve GEREÇLER: 1 Ocak 2015 ile 31 Aralık 2018 tarihleri arasında Ankara ili içerisindeki hastanelerde kan 25(OH)D vitamini seviyesi bakılan Irak ve Suriyeli göçmen çocuklar retrospektif olarak incelendi. 25 (OH) D vitamin seviyeleri <12 ng / mL eksikliği, 12-20 ng / mL yetersizliği,> 20 ng / mL normal olarak sınıflandırıldı.

BULGULAR: Çalışmaya yaş ortalaması 10.1±5.3 olan, toplam 171 göçmen çocuk dahil edildi. Çocukların %25. 7’ sinin normal (>20 ng/mL) 25(OH)D vitamini kan seviyesine sahip olduğu gözlenirken, %31.2 sinde hafif eksiklik, (12-20 ng/mL), %40.9 unda tedavi gerektiren D vitamini eksikliği (< 12 ng/mL) tespit edildi. Çocuklar cinsiyet, yaş grupları ve uyruklarına göre D vitamini seviyeleri karşılaştırıldığında kız çocukların (p=0.003) ve 10 yaş ve üzerindekilerin (p=<0.001) 25(OH)D vitamini seviyelerinin daha düşük olduğu gözlendi.

TARTIŞMA ve SONUÇ: Çalışmamız göçmen çocuklarda özellikle 10 yaş üstü ve kız çocuklarında yüksek oranda tedavi gerektiren D vitamini eksikliği olduğunu göstermektedir. Ciddi olumsuz sonuçları olabilecek D vitamini eksikliği ve yetersizliği açısından yüksek risk altında olan göçmen çocukların D vitamini takviyesi ve beslenme desteğine ihtiyaçları olduğunu düşünüyoruz

Anahtar Kelimeler

Göçmen çocuklar, Vitamin D

Kaynakça

• 1. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357(3):266-81.
• 2. Holick MF. Vitamin D: A millenium perspective. J Cell Biochem 2003; 88(2): 296-307.
• 3. Caradonna P, Rigante D. Bone health as a primary target in the pediatric age. Eur Rev Med Pharmacol Sci 2009; 13(2): 117-28.
• 4. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. Clin Endocrinol Metab 2011; 96(7): 1911-30.
• 5. Munns CF, Shaw N, Kiely M, Specker BL, Thacher TD, Ozono K, et al. Global Consensus Recommendations on Prevention and Management of Nutritional Rickets. J Clin Endocrinol Metab 2016; 101(2): 394-415.
• 6. UNHCR (2017) Global trends in forced displacement. Available from: https://www.unhcr.org/statistics/unhcrstats/5943e8a34/global-trends-forced-displacement-2016.html. Accessed in 2019 (July 31).
• 7. International Organization for Migration. MPM Turkey Migrants' Presence Monitoring - Situation Report (April 2019). Published on 30 Apr 2019. Available from:https://displacement.iom.int/system/tdf/reports/Turkey_Sitrep_04_Apr_19.pdf?file=1&type=node&id=5749. Accessed in 2019 (July 31).
• 8. Lane G, Farag M, White J, Nisbet C, Vatanparast H. Chronic health disparities among refugee and immigrant children in Canada. Appl Physiol Nutr Metab 2018; 43(10): 1043-58.
• 9. Pavlopoulou ID, Tanaka M, Dikalioti S, Samoli E, Nisianakis P, Boleti OD, et al. Clinical and laboratory evaluation of new immigrant and refugee children arriving in Greece. BMC pediatr 2017; 17(1): 132.
• 10. Lips P, de Jongh RT. Vitamin D deficiency in immigrants. Bone Rep 2018; 9: 37-41.
• 11. Pedersen P, Michaelsen KF, Molgaard C. Children with nutritional rickets referred to hospitals in Copenhagen during a 10-year period. Acta paediatr 2003; 92(1): 87-90.
• 12. Hintzpeter B, Scheidt-Nave C, Muller MJ, Schenk L, Mensink GB. Higher prevalence of vitamin D deficiency is associated with immigrant background among children and adolescents in Germany. J Nutr 2008; 138(8): 1482-90.
• 13. Holvik K, Meyer HE, Haug E, Brunvand L, et al. Prevalence and predictors of vitamin D deficiency in five immigrant groups living in Oslo, Norway: the Oslo Immigrant Health Study. Eur J Clin Nutr 2005; 59(1): 57-63.
• 14. McGillivray G, Skull SA, Davie G, Kofoed SE, Frydenberg A, Rice J, et al. High prevalence of asymptomatic vitamin D and iron deficiency in East African immigrant children and adolescents living in a temperate climate. Arch Dis Child 2007; 92(12): 1088-93.
• 15. Mansbach JM, Ginde AA, Camargo CA. Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: do children need more vitamin D?. Pediatrics 2009; 124(5): 1404-10.
• 16. Zhu Z, Zhan J, Shao J, Chen W, Chen L, Li W, et al. High prevalence of vitamin D deficiency among children aged 1 month to 16 years in Hangzhou, China. BMC public health 2012; 12: 126.
• 17. Andıran N, Çelik N, Akça H, Doğan G. Vitamin D deficiency in children and adolescents. J Clin Res Pediatr En docrinol 2012; 4(1): 25.
• 18. Hu Y, Chen J, Wang R, Li M, Yun C, Li W, et al. Vitamin D Nutritional Status and its Related Factors for Chinese Children and Adolescents in 2010-2012. Nutrients 2017; 9(9).
• 19. Vatanparast H, Nisbet C, Gushulak B. Vitamin D insufficiency and bone mineral status in a population of newcomer children in Canada. Nutrients 2013; 5(5): 1561-72.
• 20. Demiral M, Sirmagül B, Kirel B. Vitamin D Levels in Children Admitted to the Endocrine Outpatient Clinic. J Curr Pediatr 2016; 14(2).
• 21. Challa AS, Makariou SE, Siomou EC. The relation of vitamin D status with metabolic syndrome in childhood and adolescence: an update. J Pediatr Endocrinol Metab 2015; 28(11-12): 1235-45.
• 22. Szymczak-Pajor I, Sliwinska A. Analysis of Association between Vitamin D Deficiency and Insulin Resistance. Nutrients 2019; 11(4).
• 23. Wang H, Chen W, Li D, Lips P, et al. Vitamin D and Chronic Diseases. Aging and disease 2017; 8(3): 346-53.
• 24. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004; 80(6 Suppl): 1678-88.