Otizm Spektrum Bozukluğu Olan Hastalarda Risk Faktörleri Ve Dismorfolojinin İncelenmesi

Yıl 2020, Cilt: 18 Sayı: 2, 220 - 236, 01.08.2020

Dilşad Yıldız Miniksar

Öz

GİRİŞ ve AMAÇ: Çalışmamızda Otizm Spektrum Bozukluğu (OSB) tanısına sahip çocuk ve ergenlerin sosyodemografik özellikleri, prenatal- postnatal öyküleri,dismorfik bulguları ve olguların annelerinin gebelik öykülerinin araştırılması amaçlanmıştır.

YÖNTEM ve GEREÇLER: Bu prospektif tanımlayıcı çalışmaya OSB tanısı alan yaşları 5-17 arasında olan 74 çocuk ve ergen dahil edilmiştir. Bu çocukların zeka düzeyini belirlemek için Wechsler Çocuklar İçin Zeka Ölçeği (WISC –R) kullanılmıştır. Otistik semptomların şiddetini değerlendirmek için Çocukluk Otizm Derecelendirme Ölçeği (CARS) kullanılmıştır. Olguların annelerinin gebelik öyküsü, olguların prenatal ve postnatal öyküleri, varsa o zamanın görüntüleme raporları ile birlikte aile anamnezi ve epikriz kayıtları değerlendirilmiştir. Olguların fizik muayene ile baş çevresi ölçülmüş ve dismorfik bulguları Minör Konjenital Anomaliler için Yüzey Değerlendirme ölçeği kullanılarak belirlenmiştir

BULGULAR: Olguların annelerinin gebelik öyküleri, olguların prenatal-postnatal risk faktörleri ve dismorfoloji ASD etyolojisinde etkili bulunmuştur
TARTIŞMA ve SONUÇ: OSB etyolojisi karışık ve tam olarak aydınlatılamamış olmakla birlikte, çalışmamızdaki verilerle bu spektrumun risk faktörleri değerlendirilmiş, etyopatogenezinin aydınlatılmasına katkı sunulmuş ve OSB’nin önlenebilir risk faktörleri belirlenmiştir.

Anahtar Kelimeler

otizm,, risk faktörleri,, dismorfoloji,

Kaynakça

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