Relationship Between Adult Separation Anxiety Disorder and Suicide in Patients with Bipolar Disorder

Abstract

The present study aimed to investigate the comorbidity of Adult Separation Anxiety Disorder (ASAD) and the relationship between this comorbidity and suicide in patients with bipolar disorder (BD). A total of 138 outpatients with BD at remission between the ages of 18-65 years and 63 healthy controls were included in our study. All participants were administered a sociodemographic data form, Hamilton Depression Scale (HMDS), Young Mania Rating Scale (YMRS), Adult Separation Anxiety Questionnaire, and Structured Clinical Interview for Separation Anxiety Symptoms (ASAD-SCI). The age and gender of the participants did not differ significantly between the control group, the BD and BD+ASAD groups. The mean age of the participants was 42.3±11.9 years. When categorized according to gender, 42.3% of the participants were male and 57.7% were female. ASAD was detected in 46.3% of the participants. The suicide attempt rate was significantly higher in the BD and BD+ASAD groups than in the control group. The rate of suicide attempt was significantly higher in the BD+ASAD group than in the BD group. We demonstrated that the comorbidity of ASAD was associated with previous suicide attempts in patients with BD. Recognizing and treating ASAD in patients with BD may reduce suicide attempts in these patients.

Keywords

• Bipolar disorder
• suicidality
• separation anxiety

Bipolar Bozukluk Tanılı Hastalarda Yetişkin Ayrılma Anksiyete Bozukluğu ve İntihar Arasındaki İlişki

Öz

Çalışmamızda bipolar bozukluk (BB) tanılı hastalarda Yetişkin Ayrılma Anksiyete Bozukluğu (YAAB) komorbiditesi ve bu komorbiditenin intihar ile ilişkisinin araştırılması amaçlanmıştır. Çalışmamıza ayaktan izlenen remisyonda BB tanılı 18-65 yaşları arasındaki 138 hasta ve 63 sağlıklı kontrol alınmıştır. Tüm katılımcılara tarafımızca hazırlanmış sosyodemografik veri formu, Hamilton Depresyon Ölçeği (HMDÖ), Young Mani Derecelendirme Ölçeği (YMDÖ), Yetişkin ayrılma anksiyete anketi, Ayrılma Anksiyetesi Belirtileri için Yapılandırılmış Klinik Görüşme (AAB-YKG) verilmiştir. Kontrol grubu, BB ve BB+YAAB grupları arasında katılımcıların yaşları ve cinsiyetleri anlamlı farklılık göstermemiştir. Katılımcıların yaş ortalaması 42,3±11,9 olarak tespit edilmiştir. Cinsiyet durumuna göre kategorize edildiğinde katılımcıların % 42,3’ü erkek olup % 57,7’si kadınlardan oluşmaktadır. Katılımcıların % 46,3’ünde YAAB tepit edilmiştir.BB ve BB+YAAB gruplarında intihar girişim oranı kontrol grubundan anlamlı olarak daha yüksekti. BB+YAAB olan grupta intihar girişim oranı BB grubundan anlamlı olarak daha yüksekti. Sonuçlarımız, BB tanılı hastalarda YAAB komorbiditesinin önceki intihar girişimleriyle ilişkili olduğunu göstermiştir. BB tanılı hastalarda YAAB’nin tanınması ve tedavi edilmesi bu hastalarda intihar girişimini azaltabilir.

Anahtar Kelimeler

• bipolar bozukluk
• intihar
• ayrılma anksiyetesi
• Bipolar disorder
• suicidality
• separation anxiety

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