Yıl 2018, Cilt 10 , Sayı 1, Sayfalar 19 - 39 2018-03-31

Attention Deficit Hyperactivity Disorder and Genetics
Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik

Fatih Hilmi ÇETİN [1] , Yasemen IŞIK [2]


Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder of which three basic symptoms are lack of attention, over-activity that is improper to the age and impulsivity, all of which appear in childhood. Its incidence is %5-12 in children and %4.4 in adults throughout the world. ADHD provides a basis for important problems for both patient, family and society and thus it is important to diagnose the disorder early and understand the factors that create predisposition to the disorder. ADHD is a multifactorial disorder with an etiology of genetic and environmental com-ponents. The importance of genetic factors first implied by Cantwell and Morrison is supported by many studies ever since. All these studies showed that inheritance rate of ADHD is as high as %76. The aim of this article is to explain ADHD genetics in categorization of twin studies, adoption studies, family studies, segregation analyzes and molecular genetic researches and to review the genetic component of ADHD.
Dikkat Eksikliği Hiperaktivite Bozukluğu (DEHB) üç temel özelliği çocukluk döneminde başlayan dikkatsizlik, gelişimsel düzeye uygun olmayan aşırı hareketlilik ve dürtüsellik olan nörogelişimsel bir bozukluktur. Dünya çapında yaygınlığı çocuklarda %5-12 ve yetişkinlerde %4.4 kadardır. DEHB hem birey hem de aile ve toplum açısından önemli sorunlara zemin hazırlamaktadır ve bu nedenle bozuk-luğun erken tanınması ve aynı zamanda bozukluğa yatkınlık oluşturan faktörlerin anlaşılması önemli-dir. DEHB, etyolojisinde genetik ve çevresel faktörlerin rol oynadığı multifaktöriyel bir bozukluktur. Yapılan tüm çalışmalar DEHB’nin kalıtılabilirlik oranının %76 gibi hayli yüksek bir oranda olduğunu göstermiştir. Bu yazıda DEHB genetiği ikiz çalışmaları, evlat edinme çalışmaları, aile çalışmaları, segregasyon analizleri ve moleküler genetik çalışmalar şeklinde sınıflandırılarak anlatılmış ve DEHB’nin genetik yönünün gözden geçirilmesi amaçlanmıştır.
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Bölüm Derleme
Yazarlar

Orcid: 0000-0002-2167-7542
Yazar: Fatih Hilmi ÇETİN

Yazar: Yasemen IŞIK

Tarihler

Kabul Tarihi : 20 Nisan 2021
Yayımlanma Tarihi : 31 Mart 2018

Bibtex @derleme { pgy334547, journal = {Psikiyatride Güncel Yaklaşımlar}, issn = {1309-0658}, eissn = {1309-0674}, address = {}, publisher = {Lut TAMAM}, year = {2018}, volume = {10}, pages = {19 - 39}, doi = {10.18863/pgy.334547}, title = {Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik}, key = {cite}, author = {Çetin, Fatih Hilmi and Işık, Yasemen} }
APA Çetin, F , Işık, Y . (2018). Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik . Psikiyatride Güncel Yaklaşımlar , 10 (1) , 19-39 . DOI: 10.18863/pgy.334547
MLA Çetin, F , Işık, Y . "Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik" . Psikiyatride Güncel Yaklaşımlar 10 (2018 ): 19-39 <https://dergipark.org.tr/tr/pub/pgy/issue/30902/334547>
Chicago Çetin, F , Işık, Y . "Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik". Psikiyatride Güncel Yaklaşımlar 10 (2018 ): 19-39
RIS TY - JOUR T1 - Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik AU - Fatih Hilmi Çetin , Yasemen Işık Y1 - 2018 PY - 2018 N1 - doi: 10.18863/pgy.334547 DO - 10.18863/pgy.334547 T2 - Psikiyatride Güncel Yaklaşımlar JF - Journal JO - JOR SP - 19 EP - 39 VL - 10 IS - 1 SN - 1309-0658-1309-0674 M3 - doi: 10.18863/pgy.334547 UR - https://doi.org/10.18863/pgy.334547 Y2 - 2021 ER -
EndNote %0 Psikiyatride Güncel Yaklaşımlar Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik %A Fatih Hilmi Çetin , Yasemen Işık %T Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik %D 2018 %J Psikiyatride Güncel Yaklaşımlar %P 1309-0658-1309-0674 %V 10 %N 1 %R doi: 10.18863/pgy.334547 %U 10.18863/pgy.334547
ISNAD Çetin, Fatih Hilmi , Işık, Yasemen . "Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik". Psikiyatride Güncel Yaklaşımlar 10 / 1 (Mart 2018): 19-39 . https://doi.org/10.18863/pgy.334547
AMA Çetin F , Işık Y . Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik. pgy. 2018; 10(1): 19-39.
Vancouver Çetin F , Işık Y . Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik. Psikiyatride Güncel Yaklaşımlar. 2018; 10(1): 19-39.
IEEE F. Çetin ve Y. Işık , "Dikkat Eksikliği Hiperaktivite Bozukluğu ve Genetik", Psikiyatride Güncel Yaklaşımlar, c. 10, sayı. 1, ss. 19-39, Mar. 2018, doi:10.18863/pgy.334547