BibTex RIS Kaynak Göster

Evaluation of Scintigraphic Image Quality in Thyroid Nodules

Yıl 2018, Cilt: 1 Sayı: 1, 11 - 18, 01.10.2018

Öz

Aim: The main goal of this study was to analyze the imaging parameters that impact image quality of nodular thyroid scintigraphy for more accurate diagnosis in nuclear medicine. Method: This work consists of two components: phantom and patients’ study. A properly designed phantom was used to mimic human’s thyroid gland. The phantom was scanned using small field of view (SFOV) gamma camera (Mediso Nucline TH-22 model) at 1 cm and 10 cm distance from the collimator. Contrast (C) and contrast-to-noise ratio (CNR) were evaluated based on ROI counts analysis. Additionally, the above mentioned C and CNR were investigated on actual thyroid images acquired up to 200.000 counts. Results: It was demonstrated that both C and CNR were higher when the distance between the detector and collimator was 1 cm. This image was also considered the optimum according to evaluation made by two experienced nuclear medicine physicians. Conclusion: The phantom and patients scintigraphy performed on gamma camera showed superior contrast and CNR with closed distances to the detector. Besides, acquisition up to 200.000 counts seems to be feasible for thyroid scintigraphy in nuclear medicine

Kaynakça

  • Bhatia B.S., Bugby S.L., Lees J.E., Perkins A.C. (2015): A scheme for assessing the performance characteristics of small field-of-view gamma cameras, Physica Medica, 31(1): 98–103.
  • Brem R.F. et al. (2005): Occult breast cancer: scintimam- mography with high-resolution breast-specific gamma camera in women at high risk for breast cancer, Radio- logy, 237(1): 274-80.
  • British Nuclear Medicine Society (BNMS) (2003): Cli- nical guidelines: Radionuclide thyroid scans, Notting- ham, http://www.bnms.org.uk/procedures-guidelines/ bnms-clinical-guidelines/radionuclide-thyroid-scans. html (07.03.2018).
  • Cherry S.R., Sorenson J.A., Phelps M.E. (2012): Physics in nuclear medicine (4th ed.), PA, USA: Elsevier.
  • Currie G.M., Towers P.A., Wheat J.M. (2006): Improved Detection and Localization of Lower Gastrointestinal Tract Hemorrhage by Subtraction Scintigraphy: Phan- tom Analysis, Journal of Nuclear Medicine Technology, 34(3): 160-168.
  • Demir M. (2014): Nükleer Tıp Fiziği ve Klinik Uygula- maları (4. Baskı), Ankara: Bayrak Matbaası, 88-91.
  • Dickerscheid D., Lavalaye J., Romijn L., Habraken J. (2013): Contrast-noise-ratio (CNR) analysis and optimi- sation of breast-specific gamma imaging (BSGI) acqu- isition protocols, European Journal of Nuclear Medicine and Molecular Imaging Research, 3(21): 2-9.
  • Hruska C.B., Weinmann A.L., O’Connor M.K. (2012): Proof of concept for low-dose molecular breast imaging with a dual-head CZT gamma camera. Part I. Evaluation in phantoms, Medical Physics, 39(6): 3466-75.
  • Jones E.A., Phan T.D., Blanchard D.A., Miley A (2009): Breast-specific γ -imaging: molecular imaging of the breast using 99mTc-sestamibi and a small-field-of-view γ -camera. , Journal of Nuclear Medicine Technology, 37(4): 201–205.
  • Rose A. (1974): The visual process. vision: optical physi- cs and engineering, Springer US.
  • Seret A (2006): A Comparison of Contrast and Sensiti- vity in Tc-99m Thyroid Scintigraphy between Nine Nuc- lear Medicine Centres of a geographic area, Alasbimn Journal, 8(32): AJ32–3.
  • Stoutjesdijk M.J. et al. (2007): Automated analysis of contrast enhancement in breast MRI lesions using mean shift clustering for ROI selection, Journal of Magnetic Re- sonance Imaging, 26(3): 606-14.
  • Tsuchimochi M., Hayama K (2013): Intraoperative gam- ma cameras for radioguided surgery: technical charac- teristics, performance parameters, and clinical applicati- ons, Physica Medica, 29(2): 126–38.
  • Turoglu T., Demir M., Güveniş A., Urgancıoğlu İ. (1993): Nükleer Tıpta Lezyon Saptanabilirliği, Turkish Journal of Nuclear Medicine, 2: 29–35.

Tiroid Nodüllerinde Sintigrafik Görüntü Kalitesinin Değerlendirilmesi

Yıl 2018, Cilt: 1 Sayı: 1, 11 - 18, 01.10.2018

Öz

Amaç: Bu çalışmada, tiroid nodüllerinde tanısal doğruluğu yüksek sintigrafik görüntü kalitesinin elde edilebilmesi için uygun çekim parametrelerinin belirlenmesi amaçlanmıştır. Yöntem: Çalışma iki aşamada gerçekleştirildi: Fantom ve hasta çalışması. Fantom çalışmasında, insan tiroidini temsil eden bir fantom Mediso Marka Nucline TH-22 model küçük görüş alanlı (SFOV) gama kamerada 99mTc kullanılarak 1 cm ve 10 cm mesafelerde görüntülendi. Fantomdaki lezyonlardan ve zeminden ilgi alanları (ROI) çizilerek kontrast (C) ve kontrast-gürültü oranı (CNR) hesaplandı. 200.000 toplam sayım değerinde çekilmiş hasta tiroid sintigrafilerinden C ve CNR parametreleri hesaplandı. Bulgular: Fantom-kolimatör mesafesi 1 cm olan sintigrafik görüntülerde, toplam sayım miktarı 200.000 olana kadar görüntülerde C ve CNR değerleri arttı. Görüntüler 2 ayrı nükleer tıp uzmanı tarafından değerlendirildi. 1 cm mesafede 200.000 sayımlı görüntü en iyi olarak yorumlandı. Kantitatif değerlendirmede ise 1 cm mesafede 200.000 sayımlı görüntünün en yüksek C ve CNR değerlerini verdiği belirlendi. Sonuç: Gama kamerada çekilen tiroid sintigrafilerinde hem fantom hem de hasta çalışmasında hastanın kolimatöre 1 cm mesafede tutulması ve çekimin 200.000 sayımda sonlandırılmasının en iyi sintigrafi kalitesi sağladığı sonucuna varıldı.

Kaynakça

  • Bhatia B.S., Bugby S.L., Lees J.E., Perkins A.C. (2015): A scheme for assessing the performance characteristics of small field-of-view gamma cameras, Physica Medica, 31(1): 98–103.
  • Brem R.F. et al. (2005): Occult breast cancer: scintimam- mography with high-resolution breast-specific gamma camera in women at high risk for breast cancer, Radio- logy, 237(1): 274-80.
  • British Nuclear Medicine Society (BNMS) (2003): Cli- nical guidelines: Radionuclide thyroid scans, Notting- ham, http://www.bnms.org.uk/procedures-guidelines/ bnms-clinical-guidelines/radionuclide-thyroid-scans. html (07.03.2018).
  • Cherry S.R., Sorenson J.A., Phelps M.E. (2012): Physics in nuclear medicine (4th ed.), PA, USA: Elsevier.
  • Currie G.M., Towers P.A., Wheat J.M. (2006): Improved Detection and Localization of Lower Gastrointestinal Tract Hemorrhage by Subtraction Scintigraphy: Phan- tom Analysis, Journal of Nuclear Medicine Technology, 34(3): 160-168.
  • Demir M. (2014): Nükleer Tıp Fiziği ve Klinik Uygula- maları (4. Baskı), Ankara: Bayrak Matbaası, 88-91.
  • Dickerscheid D., Lavalaye J., Romijn L., Habraken J. (2013): Contrast-noise-ratio (CNR) analysis and optimi- sation of breast-specific gamma imaging (BSGI) acqu- isition protocols, European Journal of Nuclear Medicine and Molecular Imaging Research, 3(21): 2-9.
  • Hruska C.B., Weinmann A.L., O’Connor M.K. (2012): Proof of concept for low-dose molecular breast imaging with a dual-head CZT gamma camera. Part I. Evaluation in phantoms, Medical Physics, 39(6): 3466-75.
  • Jones E.A., Phan T.D., Blanchard D.A., Miley A (2009): Breast-specific γ -imaging: molecular imaging of the breast using 99mTc-sestamibi and a small-field-of-view γ -camera. , Journal of Nuclear Medicine Technology, 37(4): 201–205.
  • Rose A. (1974): The visual process. vision: optical physi- cs and engineering, Springer US.
  • Seret A (2006): A Comparison of Contrast and Sensiti- vity in Tc-99m Thyroid Scintigraphy between Nine Nuc- lear Medicine Centres of a geographic area, Alasbimn Journal, 8(32): AJ32–3.
  • Stoutjesdijk M.J. et al. (2007): Automated analysis of contrast enhancement in breast MRI lesions using mean shift clustering for ROI selection, Journal of Magnetic Re- sonance Imaging, 26(3): 606-14.
  • Tsuchimochi M., Hayama K (2013): Intraoperative gam- ma cameras for radioguided surgery: technical charac- teristics, performance parameters, and clinical applicati- ons, Physica Medica, 29(2): 126–38.
  • Turoglu T., Demir M., Güveniş A., Urgancıoğlu İ. (1993): Nükleer Tıpta Lezyon Saptanabilirliği, Turkish Journal of Nuclear Medicine, 2: 29–35.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Research Article
Yazarlar

Mert Karagöz Bu kişi benim

Yağmur İdil Ulusoy

Özge Ulu Bu kişi benim

Hüseyin Demir Bu kişi benim

Özgür Taylan Akdağ Bu kişi benim

Deniz Azaklıoğlu Bu kişi benim

Nazenin İpek Bu kişi benim

Mustafa Demir

Yayımlanma Tarihi 1 Ekim 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 1 Sayı: 1

Kaynak Göster

MLA Karagöz, Mert vd. “Tiroid Nodüllerinde Sintigrafik Görüntü Kalitesinin Değerlendirilmesi”. Sağlık Bilimlerinde İleri Araştırmalar Dergisi, c. 1, sy. 1, 2018, ss. 11-18.