Adenovirüs ve Rotavirüs Gastroenterit Sıklığının Araştırılması

Öz

Amaç: Akut gastroenteritler, özellikle çocukluk çağında görülmekle beraber her yaş grubundan insanı etkilemekte ve tüm dünyada yaygın olarak görülen enfeksiyon hastalıkları arasında yer almaktadır. Bu çalışmada, beş yıllık süreçte hastanemizde akut gastroenterit tanısı almış çocuk ve yetişkin hastalarda adenovirüs ve rotavirüs sıklığının retrospektif olarak incelenmesi amaçlanmıştır.

 

Gereç ve Yöntemler: Bu çalışmada, 1 Ocak 2014-31 Aralık 2018 tarihlerinde Tıbbi Mikrobiyoloji Laboratuvarına gönderilen dışkı örneklerinde combo test kullanılarak rotavirüs ve adenovirüs pozitifliği retrospektif olarak değerlendirilmiştir.

 

Bulgular: Bu çalışmaya dahil edilen toplam 18938 dışkı örneğinin 2615 (%13,8)’inde viral antijenler saptanmıştır. Pozitif örneklerin 1686 (%64,5)’sı rotavirüs, 479 (%18,3)’u adenovirüs, 450 (%17,2)’si hem adenovirüs hem de rotavirüs açısından pozitif olarak tespit edilmiştir.

 

Sonuçlar: Sonuç olarak, yaptığımız çalışmada akut viral gastroenterit etkenleri arasında en sık rotavirüs antijenleri saptanmıştır. Viral antijenlerin yarısından fazlası 3 yaş altı çocuklarda saptansada, ileri yaştaki insanlarda da pozitiflik tespit edilmiştir. Akut gastroenteritli hastalardan viral antijenleri hızlı bir şekilde saptanması ampirik antibiyotik tedavisi kullanılmasının önüne geçecektir. 

Anahtar Kelimeler

• Adenovirüs
• Gastroenterit
• Rotavirüs

Investgation of Gastroenteritis Frequency Caused by Adenovirus And Rotavirus

Öz

Aim: Acute gastroenteritis appears mostly during childhood but can effect people of all ages and it is one of the most common infectious diseases worldwide. The aim of this study was to evaluate the incidence of adenovirus and rotavirus in children and adults with acute gastroenteritis in our hospital for five years period.

 

Materials and Methods: In this study, between 1 January 2014-31 December 2018 stool samples sent to Medical Microbiology Laboratory were evaluated  retrospectively according to  adenovirus and rotavirus positivity by using combo test.

 

Results: Totally 18938 stool samples included to this study and 2615 (%13.8) of the samples were identified positive for viral antigens. 1686 (%64.5%) of the samples were positive for rotavirus, 479 (18.3%) of the samples were positive for adenovirus, 450 (17.2%) of the samples were positive both for adenovirus and rotavirus.

 

Conclusions: As a result, in our study rotavirus antigens were detected the most common cause of acute viral gastroenteritis. Although more than half of the viral antigens were detected in children aged under 3 years, but positivity was also found in elderly people. Rapid detection of viral antigens from patients with acute gastroenteritis will prevent the use of empirical antibiotic therapy.

Anahtar Kelimeler

• Adenovirus
• Gastroenteritis
• Rotavirus

Kaynakça

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