Microencapsulation of Hemp Oil with Gelatin and Sodium Alginate Polymers and Investigation of Release Properties

Öz

Hemp oil is an oil used for different purposes around the world. In this study, hemp oil with different properties was microencapsulated by complex coacervation method in an experiment set formed with gelatin (GE) and sodium alginate (ALG). Stirring speed, temperature and surfactant concentration were chosen as input factors and the relationship between percent encapsulation efficiency (EE%) was investigated. The obtained results were optimized to maximize and the release properties in hexane medium were investigated. In the results obtained, the p value of the lack-of-fit was found to be 0.060. Since p>0.050, the data matches the model created. Maximize optimized results were calculated as 63.491% at 1460.310 rpm stirring speed, 56.897 ℃ temperature and 0.827% w/v surfactant concentration, and it was found to be 62.780% in the experiment. Obtained microcapsules were characterized by FT-IR, optical microscope and SEM devices. When the optical microscope images were examined, it was determined that the microcapsules were smooth and round in shape.

Anahtar Kelimeler

• Gelatine
• Sodium Alginate
• Hemp Oil
• Encapsulation
• Release
• Experimental Design

Jelatin ve Sodyum Aljinat Polimerleriyle Kenevir Yağının Mikroenkapsülasyonu ve Salınım Özelliklerinin İncelenmesi

Öz

Kenevir yağı dünyada farklı amaçlar için kullanılan bir yağdır. Farklı özelliklere sahip olan kenevir yağı bu çalışmada jelatin (JE) ve sodyum aljinat (ALJ) ile oluşturulan bir deney setinde kompleks koaservasyon yöntemiyle mikroenkapsüle edilmiştir. Karıştırma hızı, sıcaklık ve surfaktan derişimi giriş faktörleri olarak seçilmiş ve yüzde enkapsülasyon verimi (%EV) ile arasındaki ilişki incelenmiştir. Elde edilen sonuçlar maksimize olarak optimize edilmiş ve hekzan ortamında salınım özellikleri incelenmiştir. Elde edilen sonuçlarda model uyumsuzluğunun p değeri 0,060 bulunmuştur. p>0,050 olduğu için oluşturulan model ile veri uyuşmaktadır. Maksimize olarak optimize edilen sonuçlar 1460,310 rpm karıştırma hızı, 56,897 ℃ sıcaklık ve %0,827 a/h surfaktan derişiminde verim değeri %63,491 hesaplanmış ve yapılan deneyde %62,780 olarak bulunmuştur. Elde edilen mikrokapsüller FT-IR, optik mikroskop ve SEM cihazları ile karakterize edilmiştir. Optik mikroskop görüntüleri incelendiğinde mikrokapsüllerin düzgün, yuvarlak şeklinde olduğunu belirlenmiştir.

Anahtar Kelimeler

• Kenevir yağı
• Enkapsülasyon
• Salınım
• Jelatin
• Sodyum Aljinat
• Deney Tasarımı

Kaynakça

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