Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides

Sefa Celık; Serda Kecel Gunduz

doi:10.19113/sdufbed.12478

Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides

Öz

In this study, eight possible stable conformers of the Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) dipeptides, which show the most significant inhibition in cervical carcinoma cells opposite to HT-29 and MCF-7 cells, performed depending on the obtained conformational analysis. The possible stable geometries were determined with the aid of φ, Ψ backbone and c chain dihedral angles. Available all conformers and their energies were calculated and made comparison with the quantum chemical ab-initio results. The Van der Waals, electrostatic , torsional , interaction energies between side and main chains of aminoacids and total energies of cysteine containing dipeptides were computed by using Fortran program.

Anahtar Kelimeler

Cyclic dipeptides,Conformational analysis; DFT

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Sefa Celık

Serda Kecel Gunduz

Yayımlanma Tarihi

11 Mayıs 2017

Gönderilme Tarihi

14 Şubat 2017

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2017 Cilt: 21 Sayı: 2

DOI

https://doi.org/10.19113/sdufbed.12478

IZ

https://izlik.org/JA69UY36SN

Kaynak Göster

RIS / Bibtex

APA

Celık, S., & Kecel Gunduz, S. (2017). Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 21(2), 306-310. https://doi.org/10.19113/sdufbed.12478

AMA

1.Celık S, Kecel Gunduz S. Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 2017;21(2):306-310. doi:10.19113/sdufbed.12478

Chicago

Celık, Sefa, ve Serda Kecel Gunduz. 2017. “Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides”. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi 21 (2): 306-10. https://doi.org/10.19113/sdufbed.12478.

EndNote

Celık S, Kecel Gunduz S (01 Ağustos 2017) Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi 21 2 306–310.

IEEE

[1]S. Celık ve S. Kecel Gunduz, “Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides”, Süleyman Demirel Üniv. Fen Bilim. Enst. Derg., c. 21, sy 2, ss. 306–310, Ağu. 2017, doi: 10.19113/sdufbed.12478.

ISNAD

Celık, Sefa - Kecel Gunduz, Serda. “Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides”. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi 21/2 (01 Ağustos 2017): 306-310. https://doi.org/10.19113/sdufbed.12478.

JAMA

1.Celık S, Kecel Gunduz S. Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 2017;21:306–310.

MLA

Celık, Sefa, ve Serda Kecel Gunduz. “Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides”. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, c. 21, sy 2, Ağustos 2017, ss. 306-10, doi:10.19113/sdufbed.12478.

Vancouver

1.Sefa Celık, Serda Kecel Gunduz. Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 01 Ağustos 2017;21(2):306-10. doi:10.19113/sdufbed.12478

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