The Effect of Synthesis Conditions on Calcium Silicate Bioceramic Materials

Yıl 2019, Cilt: 23 Sayı: 3, 727 - 737, 25.12.2019

Yasin Arslan , Erdal Kenduzler , Vahide Tuğçe Adıgüzel Fatma Tomul

https://doi.org/10.19113/sdufenbed.527602

Cited By: 4

Öz

In
this study, calcium silicate bioceramic materials of various Ca/Si ratios were
prepared using tetraethyl orthosilicate and calcium nitrate by a hydrothermal
synthesis method, taking into consideration cost-effective and environmentally
friendly, ‘green’, synthesis rules. For comparison purposes, sol-gel synthesis
method was also used. Calcium silicate bioceramic materials produced by both
methods were calcined at 600°C and 950°C. Fourier Transform Infrared
Spectroscopy, Thermogravimetric Thermal Analysis, Field Emission Scanning
Electron Microscopy and X-ray Diffraction methods were used to characterize calcium
silicate bioceramic materials. The characterization results validated the
formation of calcium silicate materials.

Anahtar Kelimeler

Calcium silicate bioceramic, Materials, Hydrothermal synthesis, Calcination, X-ray diffraction

Sentez Koşullarının Kalsiyum Silikat Biyoseramik Malzemelere Etkisi

Öz

Bu
çalışmada, çeşitli Ca/Si oranlarındaki kalsiyum silikat biyoseramik
malzemeleri, düşük maliyetli ve çevre dostu "yeşil" sentez kuralları
göz önünde bulundurularak, bir hidrotermal sentez yöntemi ile hazırlanmıştır.
Karşılaştırma amacıyla sol-gel sentez metodu da kullanılmıştır. Başlangıç
materyali olarak tetraetil ortosilikat ve kalsiyum nitrat kullanılmıştır. Her
iki yöntemle üretilen kalsiyum silikat biyoseramik malzemeleri 600 °C ve 950
°C'de kalsine edilmiştir. Fourier Dönüşümü Kızılötesi Spektroskopisi,
Termogravimetrik Termal Analiz, Alan Emisyon Taramalı Elektron Mikroskobu ve X-Işını
Kırınımı metodları kalsiyum silikat biyoseramik malzemeleri karakterize etmek
için kullanılmıştır. Karakterizasyon sonuçları kalsiyum silikat malzemelerinin
oluşumunu doğrulamıştır.

Anahtar Kelimeler

Kalsiyum silikat biyoseramik, Malzemeler, Hidrotermal sentez, Kalsinasyon, X ışını kırınımı

Kaynakça

• [1] Ho, C.-C., Wei, C.-K., Lin, S.-Y., Ding, S.-J. 2016. Calcium silicate cements prepared by hydrothermal synthesis for bone repair. Ceram. Int., 42, 9183-9189.
• [2] Niu, L., Jiao, K., Wang, T., Zhang, W., Camilleri, J., Bergeron, B.-E., Feng, H., Mao, J., Chen, J., Pashley, D.-H., Tay, F.-R. 2014. A review of the bioactivity of hydraulic calcium silicate cements. J. Dentistry., 42, 517-533.
• [3] Sun, Y.-S., Li, A.-L., Renb, H.-H., Zhang, X.-P., Wang, C., Qiu, D. 2016 Removal of residual nitrate ion from bioactive calcium silicate through soaking. Chin. Chem. Lett., 27, 579–582.
• [4] Ding, S.-J., Shie, M.-Y., Wei, C.-K. 2011. In vitro physicochemical properties, osteogenic activity, and immunocompatibility of calcium silicate–gelatin bone grafts for load-bearing applications. ACS Appl Mater Interfaces., 3, 4142-4153.
• [5] Giannoulatou, V., Theodorou, G.-S., Zorba, T., Kontonasaki, E., Papadopoulou, L., Kantiranis, N., Paraskevopoulos, K.-M. 2018. Magnesium calcium silicate bioactive glass doped with copper ions; synthesis and in-vitro bioactivity characterization. Journal of Non-Crystalline Solids, 500, 98-109.
• [6] Chen, L., Deng, C., Li, J., Yao, Q., Chang, J., Wang, L., Wu, C. 2019. 3D printing of a lithium-calcium-silicate crystal bioscaffold with dual bioactivities for osteochondral interface reconstruction. Biomaterials, 196, 138-150.
• [7] Zhang, Q., Chen, L., Chen, B., Chen, C., Chang, J., Xiao, Y., Yan, F. 2019. Lithium-calcium-silicate bioceramics stimulating cementogenic/ osteogenic differentiation of periodontal ligament cells and periodontal regeneration. Applied Materials Today, 16, 375-387.
• [8] Liu, C.-H., Hung, C.J., Huang, T.H., Lin, C.C., Kao, C.T., Shie, M.Y. 2014. Odontogenic differentiation of human dental pulp cells by calcium silicate materials stimulating via FGFR/ERK signaling pathway, Materials Science and Engineering: C, 43, 359-366.
• [9] Lu, B.Q., Zhu, Y.J., Ao, H.Y., Qi, C., Chen, F. 2012. Synthesis and Characterization of Magnetic Iron Oxide/Calcium Silicate Mesoporous Nanocomposites as a Promising Vehicle for Drug Delivery, ACS Applied Materials Interfaces, 4, 6969−6974.
• [10] Shirazi, F.S., Mehrali, M., Oshkour, A.A., Metselaar, H.S.C., Kadri, N.A., Osman, N.A.A. 2014. Mechanical and physical properties of calcium silicate/alumina composite for biomedical engineering applications, Journal of the Mechanical Behavior of Biomedical Materials, 30, 168-175.
• [11] Chen, C.C., Ho, C.-C., Lin, S.Y., Ding, S.J. 2015. Green synthesis of calcium silicate bioceramic powders, Ceram. Int., 41, 5445–5453.
• [12] Li, M., Liang, H. 2004. Formation of micro-porous spherical particles of calcium silicate (xonotlite) in dynamic hydrothermal process. China Particuology, 2, 124-127.
• [13] Mehrali, M. Shirazi, S.-F.-S. Baradaran, S.; Mehrali, M.; Metselaar, H.-S.-C.; Bin Kadri, N.-A.;Osman, N.-A.-A. 2014. Facile synthesis of calcium silicate hydrate using sodium dodecyl sulfate as a surfactant assisted by ultrasonic irradiation. Ultrason. Sonochem. 21, 735–742.
• [14] Roosz, C., Gaboreau, S., Grangeon, S., Prêt, D., Montouillout, V., Maubec, N., Ory, S., Blanc, P., Vieillard, P., Henocq, P. 2016. Distribution of water in synthetic calcium silicate hydrates. Langmuir. 32, 6794–6805.
• [15] Yongjia, H., Xiaogang, Z., Linnu, L., Leslie, S., Shuguang, H. 2011. Effect of C/S Ratio on Morphology and Structure of Hydrothermally Synthesized Calcium Silicate Hydrate. J Wuhan Univ. Technol., 26, 770-773.
• [16] Hench, L.-L., West, J.-K. 1990. The sol-gel process. Chem. Rev., 90, 33-72.
• [17] Li, P., De Groot, K. 1994. Better bioactive ceramics through sol-gel process. J. Sol-Gel Sci. Technol., 2, 797-806.
• [18] Meiszterics, A., Sinkό, K. 2008. Sol-gel derived calcium silicate seramics. Colloids Surf. A Physicochem. Eng. Asp., 319, 143-148.
• [19] Zhang, N., Liu, W., Zhu, H., Chen, L., Lin, K., Chang, J. 2014. Tailoring Si-substitution level of Si-hydroxy apatite nanowires via regulating Si content of calcium silicates as hydrothermal precursors. Ceram. Int., 40, 11239-11243.
• [20] Tas, A. -C. 2000. Synthesis of biomimetic Ca-hydroxyapatite powders at 37 C in synthetic body fluids. Biomaterials, 21, 1429-1438.
• [21] Lakshmi, R., Sasikumar, S. 2015. Influence of needle-like morphology on the bioactivity of nanocrystalline wollastonite–an in vitro study. Int. J. Nanomedicine., 10, 129-136.
• [22] Wang, F., Xu, Z., Zhang, Y., Li, J., Nian, S., Zhou, N. 2016. Green synthesis and bioactivity of vaterite-doped beta-dicalcium silicate bone cement. Ceram. Int., 42, 1856-1861.
• [23] Ciprioti, S.-V., Catauro, M. 2016. Synthesis, structural and thermal behavior study of four Ca-containing silicate gel-glasses. J. Therm. Anal. Calorim., 123, 2091–2101.
• [24] Akat’eva, L.-V., Gladun, V.-D., Khol’kin, A.-I. 2011. Use of Extractants in the Synthesis of Calcium Silicates and Calcium Silicate–Based Materials. Theor. Found. Chem. Eng., 45, 702–712.
• [25] Lin, K., Chang, J., Chen, G., Ruan, M., Ning, C. 2007. A simple method to synthesize single-crystalline β-wollastonite nanowires. J. Cryst. Growth. 300, 267-271.
• [26] Chiang, T.-Y., Wei, C.-K., Ding, S.-J. 2013. Effects of Bismuth Oxide on Physicochemical Propertiesand Osteogenic Activity of Dicalcium Silicate Cements. J. Med. Biol. Eng., 34, 30-35.
• [27] Baciu, D., Simitzis, J. 2007. Synthesis and characterization of a calcium silicate bioactive glass. Optoelectron. Adv. Mat., 9, 3320-3324.
• [28] Meiszterics, A., Rosta, L., Peterlik, H., Rohonczy, J., Kubuki, S., Henits, P., Sinkó, K. 2010. Structural characterization of gel-derived calcium silicate systems. J. Phys. Chem. A., 114, 10403-10411.
• [29] Lee, Y.-L., Wang, W.-H., Lin, F.-H., Lin, C.-P. 2017. Hydration behaviors of calcium silicate-based biomaterials. J. Formos. Med. Assoc., 116, 424-431. [30] Lakshmi, R., Sasikumar, S. 2015. Influence of needle-like morphology on the bioactivity of nanocrystalline wollastonite–an in vitro study. Int. J Nanomedicine., 10, 129-136.
• [31] Padilla, S., Roman, J., Carenas, A., Vallet-Regi, M. 2005. The influence of the phosphorus content on the bioactivity of sol–gel glass ceramics. Biomaterials., 26, 475-483.
• [32] Foley, E.-M., Kim, J.-J., Taha, M.-R. 2012. Synthesis and nano-mechanical characterization of calcium-silicate-hydrate (CSH) made with 1.5 CaO/SiO2 mixture. Cem. Concr. Res., 42, 1225-1232.
• [33] Sun, Y.-S., Li, A.-L., Xu, F.-J., Qiu, D. 2013. A low-temperature sol–gel route for the synthesis of bioactive calcium silicates. Chin. Chem. Lett., 24, 170–172.