Is There Any Correlation Between The Grade of Coronary Collaterals and Vitamin D Levels In Patients with Coronary Chronic Total Occlusion?

Yıl 2019, , 206 - 211, 20.09.2019

Çağın Mustafa Üreyen , Kahraman Coşansu

https://doi.org/10.22312/sdusbed.567536

Öz

Objective:
There
have been studies which revealed a possible relation with the grade of coronary
collateral circulation (CCC) and the level of Vitamin D in the literature. The
objective of this study was to assess whether there is a correlation between
the grade of CCC and the level of Vitamin D according to both Rentrop and
Werner classifications in patients with coronary chronic total occlusion (CTO)
who underwent percutaneous coronary intervention.

Material-Method:
The
present study is a single-centre, retrospective cohort study. A total of 101
consecutive patients, who were hospitalized to undergo coronary CTO procedure,
were enrolled in the study. The patients were classified into 3 groups with
regard to the grade of CCC according to both Rentrop and Werner classifications.
These groups were compared with each other according to the 25(OH)VitD₃ levels.

Results:
There
was no significant difference among 3 groups with regard to 25(OH)VitD₃ levels
when the patients were classified according to the Rentrop classification
[Rentrop 1: 15.7 ng/ml (7.0-77.0 ng/ml), Rentrop 2: 16.9 ng/ml (7.0-71.3),
Rentrop 3: 16.6 ng/ml (7.0-28.7), p=0.925]. Moreover, there was no significant
difference among 3 groups with regard to 25(OH)VitD₃ levels when the
patients were classified according to the Werner classification. [Werner 0:
19.6 ng/ml (7.0-77.0 ng/ml), Werner 1: 16.6 ng/ml (7.0-71.3), Werner 2: 17.0
ng/ml (7.0-28.3), p=0.411].

Conclusion:
We
deem that there may not be a direct correlation (one-to-one relationship)
between the level of 25(OH)VitD₃ and the grade of CCC in clinical
practice.  

Anahtar Kelimeler

Collateral circulation, Coronary occlusion, Percutaneous coronary intervention, Vitamin D

Teşekkür

We would like to thank to Işın ÜREYEN, MD for her contribution to the statistical analysis of the present study.

The Relation Between The Grade of Coronary Collaterals and Vitamin D Levels

Öz

Amaç:
Literatürde
koroner kollateral dolaşımın (KKD) derecesi ile D vitamini seviyesi arasında
muhtemel bir ilişki olabileceğine dair yayınlar mevcuttur. Bu çalışmanın amacı
kronik total oklüzyon (KTO) nedeniyle perkütan koroner girişim yapılan
hastalarda hem Rentrop hem de Werner sınıflandırmasına göre KKD ile D vitamini
seviyesi arasında bir ilişki olup olmadığının araştırılmasıdır.

Materyal-Metot:
Mevcut
çalışma tek-merkezli, retrospektif kohort çalışmasıdır. KTO işlemi için
hastaneye yatırılan ardışık 101 hasta çalışmaya alınmıştır. Hastalar KKD
derecesine göre hem Rentrop hem de Werner sınıflandırmasına göre üçer gruba
ayrılmıştır. Her bir grup 25(OH)VitD₃ seviyesine göre birbiriyle
kıyaslanmıştır.

Bulgular:
Hastalar
Rentrop sınıflandırmasına göre üç
gruba ayrıldığında gruplar arasında
25(OH)VitD₃ seviyesi açısından fark saptanmamıştır [Rentrop 1: 15,7
ng/ml (7,0-77,0 ng/ml), Rentrop 2: 16,9 ng/ml (7,0-71,3), Rentrop 3: 16,6 ng/ml
(7,0-28,7), p=0,925]. Hastalar Werner sınıflandırmasına göre tekrar üç gruba sınıflandırıldığında
yine gruplar arasında 25(OH)VitD₃ seviyesi açısından fark
saptanmamıştır [Werner 0: 19,6 ng/ml (7,0-77,0 ng/ml), Werner 1: 16,6 ng/ml
(7,0-71,3), Werner 2: 17,0 ng/ml (7,0-28,3), p=0,411].

Sonuç: Çalışma sonucuna göre 25(OH)VitD₃ seviyesi ile KKD derecesi arasında klinik
pratikte bire bir ilişki olmadığı kanaatindeyiz. 

Anahtar Kelimeler

Kollateral dolaşım, Koroner oklüzyon, Perkütan koroner girişim, D vitamini

Kaynakça

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