The Relation Between The Grade of Coronary Collaterals and Vitamin D Levels

Öz

Amaç: Literatürde koroner kollateral dolaşımın (KKD) derecesi ile D vitamini seviyesi arasında muhtemel bir ilişki olabileceğine dair yayınlar mevcuttur. Bu çalışmanın amacı kronik total oklüzyon (KTO) nedeniyle perkütan koroner girişim yapılan hastalarda hem Rentrop hem de Werner sınıflandırmasına göre KKD ile D vitamini seviyesi arasında bir ilişki olup olmadığının araştırılmasıdır.

Materyal-Metot: Mevcut çalışma tek-merkezli, retrospektif kohort çalışmasıdır. KTO işlemi için hastaneye yatırılan ardışık 101 hasta çalışmaya alınmıştır. Hastalar KKD derecesine göre hem Rentrop hem de Werner sınıflandırmasına göre üçer gruba ayrılmıştır. Her bir grup 25(OH)VitD₃ seviyesine göre birbiriyle kıyaslanmıştır.

Bulgular: Hastalar Rentrop sınıflandırmasına göre üç gruba ayrıldığında gruplar arasında 25(OH)VitD₃ seviyesi açısından fark saptanmamıştır [Rentrop 1: 15,7 ng/ml (7,0-77,0 ng/ml), Rentrop 2: 16,9 ng/ml (7,0-71,3), Rentrop 3: 16,6 ng/ml (7,0-28,7), p=0,925]. Hastalar Werner sınıflandırmasına göre tekrar üç gruba sınıflandırıldığında yine gruplar arasında 25(OH)VitD₃ seviyesi açısından fark saptanmamıştır [Werner 0: 19,6 ng/ml (7,0-77,0 ng/ml), Werner 1: 16,6 ng/ml (7,0-71,3), Werner 2: 17,0 ng/ml (7,0-28,3), p=0,411].

Sonuç: Çalışma sonucuna göre 25(OH)VitD₃ seviyesi ile KKD derecesi arasında klinik pratikte bire bir ilişki olmadığı kanaatindeyiz. 

Anahtar Kelimeler

• Kollateral dolaşım,Koroner oklüzyon,Perkütan koroner girişim,D vitamini

Is There Any Correlation Between The Grade of Coronary Collaterals and Vitamin D Levels In Patients with Coronary Chronic Total Occlusion?

Öz

Objective: There have been studies which revealed a possible relation with the grade of coronary collateral circulation (CCC) and the level of Vitamin D in the literature. The objective of this study was to assess whether there is a correlation between the grade of CCC and the level of Vitamin D according to both Rentrop and Werner classifications in patients with coronary chronic total occlusion (CTO) who underwent percutaneous coronary intervention.

Material-Method: The present study is a single-centre, retrospective cohort study. A total of 101 consecutive patients, who were hospitalized to undergo coronary CTO procedure, were enrolled in the study. The patients were classified into 3 groups with regard to the grade of CCC according to both Rentrop and Werner classifications. These groups were compared with each other according to the 25(OH)VitD₃ levels.

Results: There was no significant difference among 3 groups with regard to 25(OH)VitD₃ levels when the patients were classified according to the Rentrop classification [Rentrop 1: 15.7 ng/ml (7.0-77.0 ng/ml), Rentrop 2: 16.9 ng/ml (7.0-71.3), Rentrop 3: 16.6 ng/ml (7.0-28.7), p=0.925]. Moreover, there was no significant difference among 3 groups with regard to 25(OH)VitD₃ levels when the patients were classified according to the Werner classification. [Werner 0: 19.6 ng/ml (7.0-77.0 ng/ml), Werner 1: 16.6 ng/ml (7.0-71.3), Werner 2: 17.0 ng/ml (7.0-28.3), p=0.411].

Conclusion: We deem that there may not be a direct correlation (one-to-one relationship) between the level of 25(OH)VitD₃ and the grade of CCC in clinical practice.  

Anahtar Kelimeler

• Collateral circulation,Coronary occlusion,Percutaneous coronary intervention,Vitamin D

Kaynakça

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