Hipotiroidili Hastalarda Korneal Biyomekanik Özelliklerin Değerlendirilmesi

Yıl 2019, Cilt: 10 Sayı: 4, 340 - 343, 13.12.2019

Seyfullah Kan Uğur Acar Adnan Karairahimoğlu Merve İnanç Muhammed Kızılgül Selvihan Beysel Erman Çakal

Öz

Amaç:
Hipotiroidizmin korneal biyomekanik değişikliklerle ilişkili olup olmadığını
belirlemek.

Materyal-Metot: Çalışmaya hipotiroidisi olan 48 hasta (çalışma grubu) ve
49 sağlıklı birey (kontrol grubu) alındı. Korneal histerezis (KH), korneal
rezistans faktörü (KRF) ve göz içi basıncı (GİB) dahil olmak üzere korneal
biyomekanik özellikler, oküler cevap analizörü (OCA) ile ölçüldü. GİB ayrıca
Goldmann aplanasyon tonometresi (GAT) ve merkezi kornea kalınlığı (MKK)
ultrasonik pakimetreyle ölçüldü. Çalışma ve kontrol grubu katılımcıları
arasında OCA parametreleri ve MKK'daki farklılıklar analiz edildi.

Bulgular:
Çalışma grubunda ortalama KH, KRF sırasıyla 9.7 ± 1.2 mm Hg ve 9.8 ± 1.4 idi.
Kontrol grubunda aynı değerler sırasıyla 10.0 ± 1.7 mm Hg ve 10.5 ± 2.0 idi. İki
grup arasında KH ve KRF açısından istatistiksel olarak anlamlı fark yoktu
(sırasıyla P=0.28 ve P=0.07). Korneal kompanzasyonlu GİB (17.0 ± 3.0 mm Hg’a
karşın 17.8 ± 3.7 mm Hg, P = 0.25) ve Goldmann-korelasyonlu GİB (15.7 ± 3.2 mm
Hg’a karşın 16.8 ± 4.3 mm Hg, P = 0.15) arasında anlamlı bir fark yoktu. MKK
çalışma grubu gözlerinde 551.3 ± 36.9 µm, kontrol gözlerinde 552.1 ± 41.3 µm
idi (P = 0.92).

Sonuç:
Çalışmamız hipotiroidizmin kornea biyomekanik parametreleri ve MKK değerlerini
etkilemediğini göstermektedir. Kornea biyomekanik özelliklerinin GİB
ölçümlerinin doğruluğu üzerindeki olası etkileri dikkate alınmadan hipotiroidi
hastalarında GİB ölçümlerinin güvenle kullanılabileceği sonucuna vardık.

Anahtar Kelimeler

Hipotiroidi, kornea biyomekaniği, korneal histerezis

Kaynakça

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