CHANGES IN THE DEMOGRAPHIC AND CLINICAL FEATURES OF COLORECTAL CARCINOMA CASES FOLLOWING THE COVID-19 PANDEMIC

Öz

Objective This study aimed to compare the demographic, clinical and pathological features of patients with colorectal carcinomas presenting before and after the Covid-19 pandemic. Material and Method Subjects presenting from 9 months prior to and those clinipresenting within the first 9 months of the pandemic were included in the study. The primary outcome measure of this study was the difference in the clinical and pathological features of the patients with invasive colorectal carcinomas during the two periods. Results Pre-pandemic and post-pandemic patients were similar with respect to age, gender, tumor location, tumor size, lymph node invasion, differentiation, presence of synchronous tumor, radial and distal surgical margin positivity, perineural and lymphovascular invasion, TNM stage, and liver metastasis and recurrence. Although the difference was not statistically significant when compared to the pre-pandemic period, we identified 3 patients (4.7%) with ileus and 2 patients with tumor perforation (3.2%) among post-pandemic patients. Conclusion Our findings show a slight decrease in the number of patients undergoing surgery for colorectal carcinomas in the post-pandemic period compared to the prepandemic period, probably due to the structural changes in health-care organization in hospitals and patients’ hesitation to apply for healthcare due to possible infection with SARS-CoV-2. It is evident that healthcare systems should strive to find new ways to manage serious clinical conditions such as malignancies during the Covid-19 pandemic.

Anahtar Kelimeler

• Covid-19
• Colorectal carcinomas
• Healthcare
• Delay

COVID-19 PANDEMİSİNİ TAKİBEN KOLOREKTAL KARSİNOM VAKALARININ DEMOGRAFİK VE KLİNİK ÖZELLİKLERİNDE MEYDANA GELEN DEĞİŞİKLİKLER

Öz

Amaç Bu çalışma, Covid-19 pandemisinden önce ve sonra başvuran kolorektal karsinomlu hastaların demografik, klinik ve patolojik özelliklerini karşılaştırmayı amaçladı. Gereç ve Yöntem Pandemiden 9 ay önce ve ilk 9 ay içinde başvuran olgular çalışmaya dahil edildi. Bu çalışmanın birincil sonuç ölçütü, iki dönem boyunca invaziv kolorektal karsinomlu hastaların klinik ve patolojik özelliklerindeki farklılıktı. Bulgular Pandemi öncesi ve pandemi sonrası hastalar yaş, cinsiyet, tümör yerleşimi, tümör boyutu, lenf nodu invazyonu, farklılaşma, senkron tümör varlığı, radyal ve distal cerrahi sınır pozitifliği, perinöral ve lenfovasküler invazyon, TNM evresi, karaciğer metastazı ve nüks bakımından benzerdi. Pandemi öncesi döneme göre fark istatistiksel olarak anlamlı olmasa da, pandemi sonrası hastalarda ileuslu 3 hasta (%4,7) ve tümör perforasyonu olan 2 hasta (%3,2) belirledik. Sonuç: Bulgularımız, pandemi sonrası dönemde kolorektal karsinom nedeniyle ameliyat olan hasta sayısında, muhtemelen hastanelerdeki sağlık organizasyonundaki yapısal değişiklikler ve hastaların SARS-CoV-2 ile olası enfeksiyon nedeniyle sağlık hizmetine başvuruda tereddüt etmesi nedeniyle pandemi öncesi döneme göre hafif bir azalma olduğunu göstermektedir. Sağlık sistemlerinin, Covid-19 salgını sırasında maligniteler gibi ciddi klinik durumları yönetmenin yeni yollarını bulmaya çalışması gerektiği açıktır.

Anahtar Kelimeler

• Covid-19
• Kolorektal karsinomlar
• Sağlık hizmeti
• Erteleme

Kaynakça

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