Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi

Çiğdem Küçükeşmen; Yıldırım Erdoğan

doi:10.17343/sdutfd.54798

Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi

Öz

Süleyman Demirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2009 Mart; 16 (1) Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi Çiğdem Küçükeşmen, Yıldırım Erdoğan Özet Son yıllarda estetik kaygısının artmasıyla, diş sert dokularına bağlanabilen estetik dolgu materyalleri ve adeziv sistemler geliştirilmiştir. Kullanılacak restoratif materyalin seçiminde diş, çevre dokular, hastaya bağlı faktörler ve materyalin özellikleri gibi birçok etken rol oynar. Günümüzde adeziv sistemler, genel olarak uygulama basamaklarına göre .total-etch. ve .self-etch. sistemler olarak sınıflandırılmaktadırlar ve her iki sistemin de restoratif diş hekimliğinde ve klinik uygulamalarda birbirine göre avantaj ve dezavantajları bulunmaktadır. Süt ve daimi dişlerin anatomik, histolojik ve fizyolojik özelliklerinin farklı olması nedeniyle adeziv sistemlerin bu dokulardaki etkinliği de farklılıklar göstermektedir. Adeziv sistemlerin çeşitliliği, özellikle çalışmanın zor olduğu çocuk hastalar açısından pedodontik diş hekimliğinde kolaylık ve avantaj sağlamaktadır. Çeşitli kimyasal yapılara sahip yeni materyallerin diş hekimliğinde kullanımı, bu materyal ve uygulama tekniklerinin biyolojik güvenilirliklerinin artan bir şekilde sorgulanmasına neden olmuştur. Bu biyolojik riskler karmaşıktır ve tam olarak belirlenememiştir. Adeziv teknolojisindeki hızlı ilerleme, gelecekte daha gelişmiş ve daha biyouyumlu adeziv sistemlerin ortaya çıkabileceğine işaret etmektedir. Anahtar kelimeler: asitle pürüzlendirme, total-etch sistemler, self-etch sistemler, biyouyumluluk, sitotoksisite. Abstract The efficiency, biocompatibility and cytotoxicity of bonding agents in primary and permanent teeth In recent years, restorative and adhesive materials bonded to dental hard tissues are improved because of rising aesthetic concerns of patients. There are many factors affecting the selection of dental materials such as tooth and surrounding tissues, factors belong to patients and properties of material itself. Recently, adhesive systems are classified as .total-etch. and .self-etch. and both systems have several advantages and disadvantages on clinical applications. Because of the differences between primary and permanent teeth regarding the morphology, histology and physiology, the performance of the adhesive systems are different from each other. The variety of adhesive systems provides simplicity and some advantages in pediatric dentistry in which is difficult to work with children. The use of new materials with new chemical properties has also raised questions about the biological safety of new materials. These biological risks are complex and they can not be defined completely yet. The development in the adhesive technology points that more biocompatible and advanced adhesive systems may be improved in the future. Key words: acid-etching, total-etch systems, self-etch systems,biocompatibility, cytotoxicity.

Anahtar Kelimeler

asitle pürüzlendirme, total-etch sistemler, self-etch sistemler, biyouyumluluk, sitotoksisite

Kaynakça

Jensen ME. Chapter 3: Dentin bonding agents. In:
Aschheim KW, Dale BG. Esthetic Dentistry / A clinical approach to techniques and materials, 2nd ed. St. Louis, Mosby-Year Book Inc, 2001:41-3.
Bouillaguet S. Biological risks of resin-based materials
to the dentin-pulp complex. Crit Rev Oral Biol Med. 2004;15:47-60.
McCabe JF, Walls A. Applied dental materials. Chapter
: Adhesive restorative materials: Bonding of resin based materials. 8th ed. Madlen MA-USA: Blackwell Publishing Co. 1998:169-201.
Kaaden C, Schmalz G, Powers JM. Morphological characterization of the resin-dentin interface in primary teeth. Clin Oral Investig 2003;7:235-40.
Agostini FG, Kaaden C, Powers JM. Bond strength of self-etching primers to enamel and dentin of primary teeth. Pediatr Dent 2001;23:481-6.

Hannig M, Grafe A, Atalay S, Bott B. Microleakage and SEM evaluation of fissure sealants placed by use of self-etching priming agents. J Dent 2004;32:75-81.
Swift EJ Jr. Dentin/enamel adhesives: review of the literature. Pediatr Dent 2002;24:456-61.
Dayangaç B. Kompozit rezin restorasyonlar. 2. Bölüm: Bonding sistemleri. Ankara, Güneþ Kitabevi, 2000:21- 39.
Küçükeþmen Ç, Sönmez H. Baðlayýcý sistemler/Adeziv sistemler/Mine-dentin bonding ajanlar. Akademik Dental Diþ Hekimliði Dergisi 2007;9:7-13.
Van Meerbeek B, Vargas M, Inoue S, Yoshida Y, Peumans M, Lambrechts P, Vanherle G. Adhesives and cements to promote preservation dentistry. Oper Dent (Suppl.). 2001;6:119-44.
Hashimoto M, de Geee AJ, Kaga M, Feilzer AJ. Contraction stress in dentin adhesives bonded to dentin. J Dent Res 2006;85:728-32.
Akpata ES, Behbehani J. Effect of bonding systems on post-operative sensitivity from posterior composites. Am J Dent 2006;19:151-4.
Van Landuyt K, De Munck J, Coutinho E, Peumans M, Lambrechts P, Van Meerbeek B. Bonding to Dentin: Smear layer and the process of hybridization In: G. Eliades DC, Watts T. Eliades, eds. Dental Hard Tissues and Bonding. Chapter 5. Springer-Berlin, 2005:89- 118.
Nakabayashi N, Takarada K. Effect of HEMA on bonding to dentin. Dent Mater 1992;8:125-30.
Van Meerbeek B, Dhem A, Goret-Nicaise M, Braem
M, Lambrechts P, Vanherle G. Comparative SEM and TEM examination of the ultrastructure of the resindentin interdiffusion zone. J Dent Res 1993;72:495-501.
Nakabayashi N, Pashley DH. Hybridization of dental hard tissues. Tokyo, Quintessence Publishing Co. 1998:1-106.
Miyazaki M, Onose H, Moore BK. Analysis of dentin- resin interface by use of laser raman spectroscopy. Dent Mater 2002;18:576-80.
Watanabe I, Nakabayashi N, Pashley DH. Bonding to ground dentin by a phenyl-P self etching primer. J Res Dent. 1994;73:1212-20.
Lambrechts P, Van Meerbeek B, Perdigao J, Vanherle G. Adezyon. In: Wilson NHF, Roulet JF, Fuzzi M. eds. Operatif diþ hekimliðinde geliþmeler. Cilt 2. Quintessence Yayýncýlýk, 2006:142-3.
Tay FR, Pashley DH.Aggressiveness of contemporary self-etching systems. I: Depth of penetration beyond dentin smear layers. Dent Mater 2001;17:296-308.
Frankenberger R, Perdigão J, Rosa BT, Lopes M. No- bottle vs multi-bottle dentin adhesives: a microtensile bond strength and morphological study. Dent Mater 2001; 17:373-80.
Farah JW, Powers JM. Self-etching bonding agents. The Dental Advisor, 2003:1-4.
Bouillaguet S, Gysi P,Wataha JC, Ciucchi B, Cattani M, Godin C, Meyer JM. Bond strength of composite to dentin using conventional, one-step, and self-etching adhesive systems. J Dent 2001; 29:55-61.
Tay FR, Pashley DH, Yoshiyama M. Two modes of nanoleakage expression in single-step adhesives. J Dent Res 2002; 81:472-6.
Gwinnet AJ. Structure and composition of enamel. Oper Dent. 1992;5:10-7.
Swift EJ Jr, Perdigao J, Heymann HO. Bonding to enamel and dentin: a brief history and state of the art. Quintessence Int 1995;26:95-110.
Yilmaz Y, Gurbuz T, Kocogullari ME. The influence of various conditioner agents on the interdiffusion zone and microleakage of a glass lonomer cement with a high viscosity in primary teeth. 2005;30:105-12.
Gardner A, Hobson R. Variations in acid-etch patterns with different acids and etch times. 2001;120:64-7.
Vicente A, Bravo LA, Romero M. Self-etching primer and non-rinse conditioner versus phosphoric acid: alternative methods for bonding brackets. Eur J Orthod 2006;28:173-8.
Torneck CD. Chapter 10: Dentin-Pulp Complex. In: Ten Cate AR. Oral histology: Development, Structure, and Function. 4th ed. St. Louis, Mosby-Year Book Inc, 1994:169-217.
Hosoya Y, Goto G. Resin adhesion to the ground primary enamel: influence of etching times and thermal cycling test. J Clin Pediatr Dent 1992;17:25-31.
Hallett KB, Garcia-Godoy F, Trotter AR. Shear bond strength of a resin composite to enamel etched with maleic or phosphoric acid. Aust Dent J 1994; 39:292- 7.
Cengiz T. Bölüm 4: Biyokimyasal yapý. In: Endodonti. Barýþ Yayýnlarý 3. baský Ýzmir, 1990: 43-6.
Gwinnett AJ, Tay FR, Wei SHY. Bridging the gap between overdry and overwet bonding phenomenon- optimization of dentin hybridization and tubular seal. In: Shimono M, Maseda T, Suda H, Takayashi K, eds. Dentin/pulp complex. Tokyo, Quintessence 1996:359- 63.
Ruschel HC, Chevitarese O. Density and diameter of dentinal tubules of first and second primary human molars--comparative scanning electron microscope study. J Clin Pediatr Dent. 2002;26:297-304.
Perdigão J. Dentin bonding as a function of dentin structure. Dent Clin North Am. 2002:46;277-301.
Breschi L, Perdigão J, Gobbi P, Mazzotti G, Falconi M, Lopes M. Immuno-cytochemical identification of type I collagen in acid-etched dentin. J Biomed Mater Res A. 2003;15;66:764-9.
Jacobsen T, Söderholm KJ, Garcea I, Mondragon E. Calcium leaching from dentin and shear bond strength after etching with phosphoric acid of different concentrations. Eur J Oral Sci 2000;108:247-54.
Finger WJ, Balkenhol M. Rewetting strategies for bonding to dry dentin with an acetone-based adhesive. J Adhes Dent 2000; 2:51-6.
3rd. Resin bonding to wet substrate. 1. Bonding to dentin. 1992; 23:39-41.
Tay FR, Gwinnett JA, Wei SH. The overwet phenomenon in two-component acetone-based primers containing aryl amine and carboxylic acid monomers. Dent Mater 1997; 13:118-27.
Sardella TN, de Castro FL, Sanabe ME, Hebling J. Shortening of primary dentin etching time and its implication on bond strength. J Dent 2005;33:355-62.
Hosoya Y, Kawada E, Ushigome T, Oda Y, Garcia- Godoy F. Micro-tensile bond strength of sound and caries-affected primary tooth dentin measured with original designed jig. 2006;77:241-8.
Burrow MF, Nopnakeepong U, Phrukkanon S. A comparison of microtensile bond strengths of several dentin bonding systems to primary and permanent dentin. Dent Mater 2002;18:239-45.
Pashley DH, Ciucchi B, Sano H, Horner JA. Permeability of dentin to adhesive agents. Quintessence Int. 1993;24:618-31.
Nör JE, Feigal RJ, Dennisson JB, Edwards CA. Dentin bonding: SEM comparison of the resin-dentin interface in primary and permanent teeth. J Dent Res 1996;75:1396-403.
Angker L, Swain MV, Kilpatric N. Micro-mechanical characterisation of the properties of primary tooth dentine. J Dent. 2003;31:261-7.
Kaaden C, Schmalz G, Powers JM. Morphological characterization of the resin-dentin interface in primary teeth. 2003;7:235-40.
El Kalla IH, Garcia-Godoy F. Bond strength and interfacial micromorphology of four adhesive systems in primary and permanent teeth. J Dent Child 1998;65:169-76.
Hosoya Y, Kawashita Y, Marshall GW, Goto G. Influence of CarisolvTM for resin adhesion to sound human primary dentin and young permanent dentin. J Dent 2001;29:163-71.
Burrow MF, Nopnakeepong U, Phrukkanon S. A comparison of microtensile bond strengths of several dentin bonding systems to primary and permanent dentin. Dent Mater 2002;18:239-45.
Hosoya Y, Kawashita Y, Yoshida M, Suefuji C, Marshall GW Jr. Fluoridated light activated bonding resin adhesion to enamel and dentin: Primary vs permanent. Pediatr Dent 1997;19:246-52.
Hosoya Y, Shinkawa H, Marshall GW. Influence of Carisolv on resin adhesion for two different adhesive systems to sound human primary dentin and young permanent dentin. J Dent 2005;33:283-91.
Hosoya Y, Tominaga A, Kakazu K, Nishiguchi M, Kashiwabara Y, Goto G. A comparison of three dentin adhesives to permanent dentin in regard to those of primary dentin. Pediatr Dent J 1996;6:23-32.
Nakornchai S, Harnirattisai C, Surarit R, Thiradilok S. Microtensile bond strength of a total-etching versus self-etching adhesive to caries-affected and intact dentin in primary teeth..J Am Dent Assoc 2005;136:477-83.
Nakajima M, Sano H, Burrow MF, Tagami J, Yoshiyama M, Ebisu S, Ciucchi B, Russell CM, Pashley DH. Tensile bond strength and SEM evaluation of caries-affected dentin using dentin adhesives. J Dent Res 1995;74:1679-88.
Yoshiyama M, Tay FR, Doi J, Nishitani Y, Yamada T, Itou K, Carvalho RM, Nakajima M, Pashley DH. Bonding of self-etch and total-etch adhesives to carious dentin. J Dent Res 2002;81: 556-60.
Nakajima M, Sano H, Urabe I, Tagami J, Pashley DH. Bond strengths of single-bottle dentin adhesives to caries-affected dentin. Oper Dent 2000;25:2-10.
Sarý S, Ozalp N, Ozer L. The effect of formocresol on bond strength of adhesive materials to primary dentine. J Oral Rehabil 2004;31; 671-4.
Townsend RD, Dunn WJ. The effect of saliva contamination on enamel and dentin using a self- etching adhesive. J Am Dent Assoc. 2004;135:895- 901.
Campoy MD, Vicente A, Bravo LA. Effect of saliva contamination on the shear bond strength of orthodontic brackets bonded with a self-etching primer. Angle
Orthod 2005;75:865-9.
Yoo HM, Oh TS, Pereira PN. Effect of saliva contamination on the microshear bond strength of one- step self-etching adhesive systems to dentin. Oper Dent. 2006;31:127-34.
Elkins CJ, McCourt JW Bond strength of dentinal adhesives in primary teeth. 1993;24:271-3.
Rueggeberg FA, Margeson DH. The effect of oxygen inhibition on an unfilled/filled composite system. J Dent Res 1990;69:1652-8.
Imazato S, McCabe JF, Tarumi H, Ehara A, Ebisu S. Degree of conversion of composites measured by DTA and FTIR. Dent Mater 2001;17:178-83.
Bouillaguet S, Wataha JC, Hanks CT, Ciucchi B, Holz J. In vitro cytotoxicity and dentin permeability of HEMA. J Endod 1996;22:244-8.
Ratanasathien S, Wataha JC, Hanks CT, Dennison JB. Cytotoxic interactive effects of dentin bonding components on mouse fibroblasts. J Dent Res 1995;74:1602-6.
Rakich DR, Wataha JC, Lefebvre CA, Weller RN. Effect of dentin bonding agents on the secretion of inflammatory mediators from macrophages. J Endod 1999;25:114-7.
Noda M, Wataha JC, Lockwood PE, Volkmann KR, Kaga M, Sano H. Sublethal, 2-week exposures of dental material components alter TNF-alpha secretion of THP-1 monocytes. Dent Mater 2003;19:101-5.
Bouillaguet S, Wataha JC, Virgillito M, Gonzalez L, Rakich DR, Meyer JM. Effect of sub-lethal concentrations of HEMA (2-hydroxyethyl methacrylate) on THP-1 human monocyte-macrophages, in vitro. Dent Mater 2000;16:213-7.
Lefebvre CA, Wataha JC, Bouillaguet S, Lockwood PE. Effects of long-term sub-lethal concentrations of dental monomers on THP-1 human monocytes. J Biomater Sci Polym Ed 1999;10:1265-74.
Schmalz G. The biocompatibility of non-amalgam dental filling materials. Eur J Oral Sci 1998;106:696- 706.
Galler K, Hiller K, Ettl T, Schmalz G. Selective influence of dentin thickness upon cytotoxicity of dentin contacting materials. J Endod 2005; 31:396-9.
de Souza Costa CA, Lopes do Nascimento AB, Teixeira HM, Fontana UF. Response of human pulps capped with a self-etching adhesive system. Dent Mater 2001; 17:230-40.
de Souza Costa CA, do , Teixeira HM. Response of human pulps following acid conditioning and application of a bonding agent in deep cavities. Dent Mater 2002;18:543-51.

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Çiğdem Küçükeşmen Bu kişi benim

Yıldırım Erdoğan Bu kişi benim

Yayımlanma Tarihi

30 Mart 2009

Gönderilme Tarihi

1 Haziran 2009

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2009 Cilt: 16 Sayı: 1

DOI

https://doi.org/10.17343/sdutfd.54798

IZ

https://izlik.org/JA97KS46GF

Kaynak Göster

RIS / Bibtex

APA

Küçükeşmen, Ç., & Erdoğan, Y. (2009). Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi. Medical Journal of Süleyman Demirel University, 16(1), 48-55. https://doi.org/10.17343/sdutfd.54798

AMA

1.Küçükeşmen Ç, Erdoğan Y. Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi. SDÜ Tıp Fak Derg. 2009;16(1):48-55. doi:10.17343/sdutfd.54798

Chicago

Küçükeşmen, Çiğdem, ve Yıldırım Erdoğan. 2009. “Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi”. Medical Journal of Süleyman Demirel University 16 (1): 48-55. https://doi.org/10.17343/sdutfd.54798.

EndNote

Küçükeşmen Ç, Erdoğan Y (01 Mart 2009) Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi. Medical Journal of Süleyman Demirel University 16 1 48–55.

IEEE

[1]Ç. Küçükeşmen ve Y. Erdoğan, “Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi”, SDÜ Tıp Fak Derg, c. 16, sy 1, ss. 48–55, Mar. 2009, doi: 10.17343/sdutfd.54798.

ISNAD

Küçükeşmen, Çiğdem - Erdoğan, Yıldırım. “Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi”. Medical Journal of Süleyman Demirel University 16/1 (01 Mart 2009): 48-55. https://doi.org/10.17343/sdutfd.54798.

JAMA

1.Küçükeşmen Ç, Erdoğan Y. Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi. SDÜ Tıp Fak Derg. 2009;16:48–55.

MLA

Küçükeşmen, Çiğdem, ve Yıldırım Erdoğan. “Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi”. Medical Journal of Süleyman Demirel University, c. 16, sy 1, Mart 2009, ss. 48-55, doi:10.17343/sdutfd.54798.

Vancouver

1.Çiğdem Küçükeşmen, Yıldırım Erdoğan. Süt ve daimi dişlerde bağlayıcı ajanların etkinliği, biyouyumluluğu ve sitotoksisitesi. SDÜ Tıp Fak Derg. 01 Mart 2009;16(1):48-55. doi:10.17343/sdutfd.54798