Successful use of vincristine in the management of Kasabach-Merritt Phenomenon

Cilt: 19 Sayı: 2 30 Haziran 2012
  • M Asim Aydın
  • Ayca Kuybulu
  • Aslihan Boyacı
  • Tugba Koca
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Successful use of vincristine in the management of Kasabach-Merritt Phenomenon

Öz

A 2-month old boy with Kaposiform Hemangioendothelioma of the lumbosacral region invading the retroperitoneum was admitted with Kasabach-Merritt Phenomenon. After corticosteroid and interferon treatments failed with progression of the disease to a life threatening condition, vincristine monotreatment granted a rapid rise in platelet counts, fibrinogen levels and a resolution in the enlargement of the lesion. The remission was maintained and no adverse effects were observed during the treatment. Vincristin therapy may be suggested instead of multidrugs as first line therapy in patients with KMP.

Anahtar Kelimeler

Kaynakça

  1. Hall GW: Kasabach-Merritt syndrome: pathogenesis and management. Br J Haematol 2001;112(4):851- 862.
  2. Kwok-Williams M, Perez Z, Squire R, Glaser A, Bew S, Taylor R. Radiotherapy for life-threatening mediastinal hemangioma with Kasabach-Merritt syndrome. 2007;49(5):739-44.
  3. Chung T, Hoffer FA, Burrows PE, et al. MR imaging of hepatic hemangiomas of infancy and changes seen with interferon alpha-2a treatment. Pediatr Radiol 1996;26(5):341-348.
  4. Akyuz C, Yaris N, Kutluk MT, et al. Management of cutaneous hemangiomas: a retrospective analysis of 1109 cases and comparison of conventional dose prednisolone with high-dose methylprednisolone therapy. Pediatr Hematol Oncol 2001;18(1): 47-55.
  5. Koerper MA, Addiego JE Jr, deLorimier AA, et al. Use of aspirin and dipyridamole in children with platelet trapping syndromes. J Pediatr 1983;102(2):311-314.
  6. Prost Y, Teillac D, Bodemer C, et al. Successful treatment of Kasabach -Merritt syndrome with pentoxifylline. J Am Acad Dermatol 1991;25(5 Pt 1):854-855.
  7. Dresse MF, David M, Hume H, et al. Successful treatment of Kasabach -Merritt syndrome with prednisone and epsilon-aminocaproic acid. Pediatr Hematol Oncol 1991;8(4):329-334.
  8. Ezekowitz A, Mulliken J, Folkman J. Interferon alpha therapy of haemangiomas in newborns and infants. Br J Haematol 1991;79(Suppl 1):67-68.

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

M Asim Aydın Bu kişi benim

Ayca Kuybulu Bu kişi benim

Aslihan Boyacı Bu kişi benim

Tugba Koca Bu kişi benim

Yayımlanma Tarihi

30 Haziran 2012

Gönderilme Tarihi

29 Eylül 2010

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2012 Cilt: 19 Sayı: 2

Kaynak Göster

APA
Aydın, M. A., Kuybulu, A., Boyacı, A., & Koca, T. (2012). Successful use of vincristine in the management of Kasabach-Merritt Phenomenon. Medical Journal of Süleyman Demirel University, 19(2), 55-58. https://doi.org/10.17343/sdutfd.16253
AMA
1.Aydın MA, Kuybulu A, Boyacı A, Koca T. Successful use of vincristine in the management of Kasabach-Merritt Phenomenon. SDÜ Tıp Fak Derg. 2012;19(2):55-58. doi:10.17343/sdutfd.16253
Chicago
Aydın, M Asim, Ayca Kuybulu, Aslihan Boyacı, ve Tugba Koca. 2012. “Successful use of vincristine in the management of Kasabach-Merritt Phenomenon”. Medical Journal of Süleyman Demirel University 19 (2): 55-58. https://doi.org/10.17343/sdutfd.16253.
EndNote
Aydın MA, Kuybulu A, Boyacı A, Koca T (01 Haziran 2012) Successful use of vincristine in the management of Kasabach-Merritt Phenomenon. Medical Journal of Süleyman Demirel University 19 2 55–58.
IEEE
[1]M. A. Aydın, A. Kuybulu, A. Boyacı, ve T. Koca, “Successful use of vincristine in the management of Kasabach-Merritt Phenomenon”, SDÜ Tıp Fak Derg, c. 19, sy 2, ss. 55–58, Haz. 2012, doi: 10.17343/sdutfd.16253.
ISNAD
Aydın, M Asim - Kuybulu, Ayca - Boyacı, Aslihan - Koca, Tugba. “Successful use of vincristine in the management of Kasabach-Merritt Phenomenon”. Medical Journal of Süleyman Demirel University 19/2 (01 Haziran 2012): 55-58. https://doi.org/10.17343/sdutfd.16253.
JAMA
1.Aydın MA, Kuybulu A, Boyacı A, Koca T. Successful use of vincristine in the management of Kasabach-Merritt Phenomenon. SDÜ Tıp Fak Derg. 2012;19:55–58.
MLA
Aydın, M Asim, vd. “Successful use of vincristine in the management of Kasabach-Merritt Phenomenon”. Medical Journal of Süleyman Demirel University, c. 19, sy 2, Haziran 2012, ss. 55-58, doi:10.17343/sdutfd.16253.
Vancouver
1.M Asim Aydın, Ayca Kuybulu, Aslihan Boyacı, Tugba Koca. Successful use of vincristine in the management of Kasabach-Merritt Phenomenon. SDÜ Tıp Fak Derg. 01 Haziran 2012;19(2):55-8. doi:10.17343/sdutfd.16253

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