Periferik arter embolisi geçiren atriyal fibrilasyonu olan ve olmayan hastaların CHA2DS2-VASc skoru birbirinden farklı mıdır?

Öz

Bulgular: Hastaların %59’unda AF saptandı.  AF’li hastaların yaş ortalaması,  kadın cinsiyet oranı, hipertansiyon , kalp yetmezliği , hiperlipidemi  ve inme oranı daha yüksek izlenmiştir (p<0,05). AF hastalarının ortalama CHA2DS2-VASc skoru 5,1±1,7’e 3,5±1,8 p<0,001) AF’si olmayan hastalara göre daha yüksekti. CHA2DS2-VASc skoru 1-3 aralığında olanların oranı AF si olmayan hastalarda daha yüksek iken(%41’e %23 p=0,017)  CHA2DS2-VASc skoru 7-9 aralığında olanların oranı AF grubunda daha yüksek izlenmiştir (%28’e %6 p<0,001). Hastane içi mortalite (%14’e %7 p=0,235) her iki grupta benzerdi.

Gereç ve Yöntem: Bu çalışmada ocak 2011 ve aralık 2016 tarihleri arasında periferik arteryel emboli tanısı alan 150 hastanın kayıtları geriye dönük taranmıştır. Tüm hastaların olay öncesi CHA2DS2-VASc skoru hesaplanmıştır.

Giriş: CHA2DS2-VASc skoru atriyal fibrilasyona (AF) bağlı tromboembolik komplikasyonların risk sınıflandırmasında kullanılan geçerli, pratik bir yöntemdir.  Fakat klinik pratikte kullanımı daha çok inme için olmaktadır. Bu çalışmada periferik arteriyel emboli (PAE) geçiren AF’li ve AF’li olmayan hastaların CHA2DS2-VASc skoru karşılaştırılmıştır.

Sonuç: Atriyal fibrilasyonlu  hastaların CHA2DS2-VASc skor temelli tromboembolik risk düzeyi daha yüksek olmasına rağmen, PAE oranı açısından AF’li ve AF’li olmayan hastalar arasında fark izlenmemiştir.

Anahtar Kelimeler

• Atriyal fibrilasyon
• tromboembolizm

Is CHA2DS2-VASc Score different between patients with and without atrial fibrillation suffering from peripheral arterial embolism?

Öz

Objective: CHA2DS2-VASc is a validated , straightforward and practical stratification of  thromboembolic risk score for  non-valvular atrial fibrillation (NVAF). However it is usually used for stroke. In this trial we aim to compare the CHA2DS2-VASc score between patients with and without AF suffering from peripheral arterial embolism (PAE).

Materials and Methods: We retrospectively evaluated the data registries of 150 patients who admitted to hospital due to PAE between January 2011- December 2016.  CHA2DS2-VASc score was calculated for each patient

Results: Atrial fibrillation was detected 59% of patients.  Patients with AF were elder, more often female gender, hypertension, heart failure, hyperlipidemia, stroke and transient ischemic attack (p<0.05). The rate of prior PAE was similar between two groups (p>0.05). Patients with AF had higher CHA2DS2-VASc score then those without AF (5.1±1.7 vs 3.5±1.8 p<0.001).   The rate of the patients with a CHA2DS2-VASc score 1-3  was higher in non-AF group (41% vs 23% p=0.017. However the rate of the patients with a CHA2DS2-VASc score score 7-9 was higher in AF group (28% vs 6% p<0.001). In-hospital mortality was similar between groups (14% vs 7% p=0.235).

Conclusion: Although AF patients had higher thromboembolic risk level based on CHA2DS2-VASc score. The rate of prior PAE rate was similar between AF and non-AF groups.

Anahtar Kelimeler

• Atrial Fibrillation
• Thromboembolism
• CHA2DS2-VASc score

Kaynakça

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