Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA

Fevziye Burcu Şirin

doi:10.17343/sdutfd.605545

Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA

Öz

Prenatal tarama testlerinin kullanım amacı gebeliğin erken haftalarında kromozomal anöplöidi açısından yüksek risk taşıyan gebelerin tesbit edilmesi ve her gebenin mevcut riskleri ve tercihleri göz önünde bulundurularak bilgilendirilmesidir. Son yıllarda prenatal tarama testleri geleneksel prenatal tarama testleri ve hücreden bağımsız fetal DNA (cffDNA, fetal DNA, NIPT) olarak ikiye ayrılmaktadır. Maternal kandan biyobelirteçlerin ölçülüp ultrasonografik bulgularla kombine edildiği geleneksel prenatal tarama testleri halen birinci tercih olarak önerilmektedir. cffDNA ile gebeliğin 10. haftasından itibaren maternal kanda yeni nesil sekanslama teknikleri kullanılarak fetal DNA fragmanları analiz edilmektedir. Günümüzde hangi popülasyona cffDNA testinin önerileceği, klinik kullanımda faydası, maliyeti, limitasyonları ve avantajları tartışmalı bir konudur.

Anahtar Kelimeler

prenatal tarama testleri,fetal DNA,cffDNA

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Klinik Tıp Bilimleri

Bölüm

Derleme

Yazarlar

Fevziye Burcu Şirin ^*
0000-0001-5304-1007
Türkiye

Yayımlanma Tarihi

1 Haziran 2020

Gönderilme Tarihi

16 Ağustos 2019

Kabul Tarihi

25 Ekim 2019

Yayımlandığı Sayı

Yıl 2020 Cilt: 27 Sayı: 2

DOI

https://doi.org/10.17343/sdutfd.605545

IZ

https://izlik.org/JA64UZ42RP

Kaynak Göster

RIS / Bibtex

APA

Şirin, F. B. (2020). Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA. Medical Journal of Süleyman Demirel University, 27(2), 254-260. https://doi.org/10.17343/sdutfd.605545

AMA

1.Şirin FB. Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA. SDÜ Tıp Fak Derg. 2020;27(2):254-260. doi:10.17343/sdutfd.605545

Chicago

Şirin, Fevziye Burcu. 2020. “Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA”. Medical Journal of Süleyman Demirel University 27 (2): 254-60. https://doi.org/10.17343/sdutfd.605545.

EndNote

Şirin FB (01 Haziran 2020) Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA. Medical Journal of Süleyman Demirel University 27 2 254–260.

IEEE

[1]F. B. Şirin, “Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA”, SDÜ Tıp Fak Derg, c. 27, sy 2, ss. 254–260, Haz. 2020, doi: 10.17343/sdutfd.605545.

ISNAD

Şirin, Fevziye Burcu. “Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA”. Medical Journal of Süleyman Demirel University 27/2 (01 Haziran 2020): 254-260. https://doi.org/10.17343/sdutfd.605545.

JAMA

1.Şirin FB. Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA. SDÜ Tıp Fak Derg. 2020;27:254–260.

MLA

Şirin, Fevziye Burcu. “Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA”. Medical Journal of Süleyman Demirel University, c. 27, sy 2, Haziran 2020, ss. 254-60, doi:10.17343/sdutfd.605545.

Vancouver

1.Fevziye Burcu Şirin. Prenatal Tarama Testleri ve Hücreden Bağımsız Fetal DNA. SDÜ Tıp Fak Derg. 01 Haziran 2020;27(2):254-60. doi:10.17343/sdutfd.605545

Cited By

İnvaziv Olmayan Prenatal Teste Etik Bakış

Arşiv Kaynak Tarama Dergisi

https://doi.org/10.17827/aktd.1013719

DOWN SENDROMUNUN TESPİTİNDE İNVAZİV OLMAYAN PRENATAL TEST (NIPT) UYGULAMASININ ETİK VE HUKUKİ YÖNÜ

Erciyes Üniversitesi Hukuk Fakültesi Dergisi

https://doi.org/10.58820/eruhfd.1574649