HEART INVOLVEMENT IN COVID-19 INFECTION IN CHILDREN

Öz

ABSTRACT "Coronavirus Disease 2019 (COVID-19)", which was declared as an epidemic by the World Health Organization (WHO) on March 11, 2020 and named as "Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)" is generally mild in children. In April 2020, the Pediatric Intensive Care Association in the United Kingdom issued a warning about children presenting with an unusual clinical picture coinciding with toxic shock and atypical Kawasaki disease, including pronounced gastrointestinal symptoms and myocardial involvement. After this date, similar cases began to be reported in various centers in Europe. The World Health Organization defined these cases as pediatric multisystemic inflammatory syndrome (MIS-C) on May 14, 2020. Although it has usually a mild course in children, it can be fatal when COVID-19 causes MIS-C picture. Early diagnosis and treatment is important, especially since cardiac involvement is seen in most patients with MIS-C. In this review, we wanted to evaluation of COVID-19 in terms of cardiac involvement in the light of the literature.

Anahtar Kelimeler

• MIS-C
• COVID-19
• Cardiac involvement

ÇOCUKLARDA COVİD-19 ENFEKSİYONUNDA KALP TUTULUMU,

Öz

ÖZET Dünya Sağlık Örgütü (DSÖ) tarafından 11 Mart 2020 tarihinde salgın olarak ilan edilen ve “Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)” olarak isimlendirilen “Coronavirus Disease 2019 (COVID-19)” çocuklarda genellikle hafif seyretmektedir. Nisan 2020'de Birleşik Krallık'taki Pediatrik Yoğun Bakım Derneği, belirgin gastrointestinal semptomları ve miyokardiyal tutulum da dahil olmak üzere toksik şok sendromu ve atipik Kawasaki hastalığı ile örtüşen olağandışı bir klinik tablo ile başvuran çocuklar hakkında bir uyarı yayınladı. Bu tarihten sonra Avrupa’da çeşitli merkezlerde buna benzer vakalar bildirilmeye başlandı. DSÖ 14 Mayıs 2020 tarihinde bu olguları pediatrik multisistemik inflamatuvar sendrom (MIS-C) olarak tanımlamıştır. Çocuklarda hafif seyretmekle birlikte COVID-19 hastalığı MIS-C tablosuna yol açtığında ölümcül olabilmektedir. Özellikle kalp tutulumu MIS-C hastalarının çoğunda görüldüğünden erken tanı ve tedavisi önem arz etmektedir. Bu derlemede COVID-19'u literatür ışığında kardiyak tutulum açısından değerlendirmek istedik.

Anahtar Kelimeler

• MIS-C
• Kardiyak Tutulum
• COVID-19

Kaynakça

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