BibTex RIS Kaynak Göster

Bronchopulmonary carcinoid tumors: report of 15 cases

Yıl 2013, , 60 - 64, 01.06.2013
https://doi.org/10.5505/sakaryamj.2013.19981

Öz

Objective: Bronchopulmonary carcinoid tumors are rare and constitute less than 5% of all lung tumors. In this study, we aimed to evaluate results, treatment modalities and clinical features in carcinoid tumor patients who underwent surgical operation in our clinic in the light of literature.Materials and Methods: We retrospectively reviewed 15 patients with a diagnosis of carcinoid tumor, who were surgically treated in our clinic between January 2000 and December 2010. Patient characteristics of age, gender, symptoms, localization of lesion, diagnosis, treatment modality and morbidity and mortality ratios were reviewed in addition to length of hospital duration.Results: 8 (53.3%) of cases were male and 7 (46.7%) were female. Mean age was 38.7. Typical carcinoid tumor was detected in 14 cases while atypical carcinoid tumor was determined in only one patient. Carcinoid tumor localized in main bronchus or lobar bronchi in 14 cases and peripheral localization was observed in one case. Lobectomy was performed in 8 cases (53.3%), inferior bilobectomy in 3 cases, sleeve superior lobectomy in 1 case, bronchoplastic resection in 2 cases and wedge resection in 1 case. Postoperative atelectasis developed in one patient only. Hospital mortality was not seen in any of the cases. Mean length of hospital stay was 9.2 (5-13) days.Conclusion: In bronchopulmonary carcinoid tumors, complete resection of tumor tissue while preserving normal lung tissue provides promising results.

Kaynakça

  • Fuks L, Fruchter O, Amital A, Fox BD, Abdel Rahman N, Kramer MR. Long-term follow-up of flexible bronchoscopic treatment for bronchial carcinoids with curative intent. Diagn Ther Endosc. 2009; 2009: 782961.
  • Mezzetti M, Raveglia F, Panigalli T, et al. Assessment of outcomes in typical and atypical carcinoids according to latest WHO classification. Ann Thorac Surg.2003; 76: 1838-1842.
  • Ginsberg RJ. Carcinoid tumors. In: Shields TW, Lo Cicero J, Ponn RB; eds. General Thoracic Surgery. Philadelphia: Lippincott Williams and Wilkins, 2000:1493-1504.
  • Arrigoni MG, Woolner LB, Bernatz PE. Atypical carcinoid tumors of the lung. J Thorac Cardiovasc Surg.1972; 64: 413-21.
  • Rosado de Christenson M, Abbott GF, Kirejczyk WM, Galvin JR, Travis WD. Thoracic carcinoids: radiologic-pathologic correlation. RadioGraphics 1999;19: 707-736.
  • Davilla DG, Dunn WF, Tazelaar HD, Pairolero PC. Bronchial carcinoid tumors. Mayo Clin Poc 1993; 68: 795-803.
  • Yazici Z, Topal U, Gebitekin C, Tolunay S, Tuncel E. Bronchial carcinoids: clinical and radiological findings. Turk J Diagn Intervent Radiol 2001; 7: 359-365.
  • McCaughan BC, Martini N, Bains MS. Bronchial carcinoids. Review of 124 cases. J Thorac Cardiovasc Surg 1985; 89: 8-17.
  • Magid D, Siegelman SS, Eggleston JC, Fishman EK, Zerhouni EA. Pulmonary carcinoid tumors: CT assessment. J Comput Assist Tomogr 1989; 13: 244-7.
  • Zweibel BR, Austin JHM, Grimes MM. Bronchial carcinoid tumors: Assesment with CT of location and intratumoral calsification in 31 patients. Radiology 1991; 179: 483-436.
  • Bini A, Brandolini J, Cassanelli N, et al. Typical and atypical pulmonary carcinoids: our institutional experience. Interact Cardiovasc Thorac Surg 2008; 7: 415-418.
  • Gustafsson BI, Kidd M, Chan A, Malfertheiner MV, Modlin IM. Bronchopulmonary neuroendocrine tumors. Cancer 2008; 113:5- 21
  • Belak J, Kudlac M, Zak V, Cavarga I, Kocan P, Böör A, et al. Surgical management of bronchopulmonary carcinoid tumors: experience over 8 years and review of the literature. Tumori. 2010; 96: 84-9.
  • Cao C, Yan TD, Kennedy C, Hendel N, Bannon PG, McCaughan BC. Bronchopulmonary carcinoid tumors: long-term outcomes after resection. Ann Thorac Surg. 2011; 91: 339-43.
  • Rea F, Rizzardi G, Zuin A, et al. Outcome and surgical strategy in bronchial carcinoid tumors: single institution experience with 252 patients. Eur J Cardiothorac Surg 2007; 31: 186-91.
  • Brokx H, Risse E, Paul M, et al. Initial bronchoscopic treatment for patients with intraluminal bronchial carcinoids. J Thorac Cardiovasc Surg 2007; 133: 973-978.

Bronkopulmoner karsinoid tümörler: 15 olgu sunumu

Yıl 2013, , 60 - 64, 01.06.2013
https://doi.org/10.5505/sakaryamj.2013.19981

Öz

Amaç: Bronkopulmoner karsinoid tümörler nadir olup tüm akciğer tümörlerinin %5'inden azını oluştururlar. Bu çalışmada kliniğimizde cerrahi tedavi uygulanan karsinoid tümörlü olguların klinik özellikleri, tedavi biçimleri ve sonuçlarının literatür verileri ışığında değerlendirilmesi amaçlandı. Materyal ve Metot: Ocak 2000 ve Aralık 2010 yılları arasında kliniğimizde karsinoid tümör tanısı alıp cerrahi ile tedavi edilen 15 olgu geriye dönük olarak incelendi. Hastaların yaşı, cinsiyeti, semptomlar, lezyonun lokalizasyonu, teşhisi, tedavi biçimi ve morbidite ve mortalite oranları ile hastane yatış süreleri gözden geçirildi. Bulgular: Olguların 8'i (%53.3) erkek, 7'si (%46.7) kadındı. Ortalama yaş 38.7 idi. Olgulardan 14'ünde tipik karsinoid tümör görülürken bir olguda atipik karsinoid tümör tespit edildi. Olguların 14'ünde karsinoid tümör ana bronş veya lob bronşuna yerleşirken bir olguda periferik yerleşim söz konusu idi. Olgulardan 8'ine (%53.3) lobektomi, 3 olguya bilobektomi inferior, 1 olguya sleeve üst lobektomi, 2 olguya bronkoplastik rezeksiyon ve 1 olguya wedge rezeksiyon uygulandı. Postoperatif sadece bir olguda atelektazi gelişti. Olguların hiçbirinde hastane mortalitesi gözlenmedi. Ortalama hastane yatış süresi 9.2 (5-13 gün) gün idi.Sonuç: Bronkopulmoner karsinoid tümörlerde normal akciğer dokusu korunarak tümörün tam rezeksiyonu yüz güldürücü sonuçlara sahiptir.

Kaynakça

  • Fuks L, Fruchter O, Amital A, Fox BD, Abdel Rahman N, Kramer MR. Long-term follow-up of flexible bronchoscopic treatment for bronchial carcinoids with curative intent. Diagn Ther Endosc. 2009; 2009: 782961.
  • Mezzetti M, Raveglia F, Panigalli T, et al. Assessment of outcomes in typical and atypical carcinoids according to latest WHO classification. Ann Thorac Surg.2003; 76: 1838-1842.
  • Ginsberg RJ. Carcinoid tumors. In: Shields TW, Lo Cicero J, Ponn RB; eds. General Thoracic Surgery. Philadelphia: Lippincott Williams and Wilkins, 2000:1493-1504.
  • Arrigoni MG, Woolner LB, Bernatz PE. Atypical carcinoid tumors of the lung. J Thorac Cardiovasc Surg.1972; 64: 413-21.
  • Rosado de Christenson M, Abbott GF, Kirejczyk WM, Galvin JR, Travis WD. Thoracic carcinoids: radiologic-pathologic correlation. RadioGraphics 1999;19: 707-736.
  • Davilla DG, Dunn WF, Tazelaar HD, Pairolero PC. Bronchial carcinoid tumors. Mayo Clin Poc 1993; 68: 795-803.
  • Yazici Z, Topal U, Gebitekin C, Tolunay S, Tuncel E. Bronchial carcinoids: clinical and radiological findings. Turk J Diagn Intervent Radiol 2001; 7: 359-365.
  • McCaughan BC, Martini N, Bains MS. Bronchial carcinoids. Review of 124 cases. J Thorac Cardiovasc Surg 1985; 89: 8-17.
  • Magid D, Siegelman SS, Eggleston JC, Fishman EK, Zerhouni EA. Pulmonary carcinoid tumors: CT assessment. J Comput Assist Tomogr 1989; 13: 244-7.
  • Zweibel BR, Austin JHM, Grimes MM. Bronchial carcinoid tumors: Assesment with CT of location and intratumoral calsification in 31 patients. Radiology 1991; 179: 483-436.
  • Bini A, Brandolini J, Cassanelli N, et al. Typical and atypical pulmonary carcinoids: our institutional experience. Interact Cardiovasc Thorac Surg 2008; 7: 415-418.
  • Gustafsson BI, Kidd M, Chan A, Malfertheiner MV, Modlin IM. Bronchopulmonary neuroendocrine tumors. Cancer 2008; 113:5- 21
  • Belak J, Kudlac M, Zak V, Cavarga I, Kocan P, Böör A, et al. Surgical management of bronchopulmonary carcinoid tumors: experience over 8 years and review of the literature. Tumori. 2010; 96: 84-9.
  • Cao C, Yan TD, Kennedy C, Hendel N, Bannon PG, McCaughan BC. Bronchopulmonary carcinoid tumors: long-term outcomes after resection. Ann Thorac Surg. 2011; 91: 339-43.
  • Rea F, Rizzardi G, Zuin A, et al. Outcome and surgical strategy in bronchial carcinoid tumors: single institution experience with 252 patients. Eur J Cardiothorac Surg 2007; 31: 186-91.
  • Brokx H, Risse E, Paul M, et al. Initial bronchoscopic treatment for patients with intraluminal bronchial carcinoids. J Thorac Cardiovasc Surg 2007; 133: 973-978.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Yener Aydın Bu kişi benim

Yavuz Selim İntepe Bu kişi benim

Hasan Kaynar Bu kişi benim

Atila Türkyılmaz Bu kişi benim

Atilla Eroğlu Bu kişi benim

Yayımlanma Tarihi 1 Haziran 2013
Gönderilme Tarihi 7 Eylül 2015
Yayımlandığı Sayı Yıl 2013

Kaynak Göster

AMA Aydın Y, İntepe YS, Kaynar H, Türkyılmaz A, Eroğlu A. Bronkopulmoner karsinoid tümörler: 15 olgu sunumu. Sakarya Tıp Dergisi. Haziran 2013;3(2):60-64. doi:10.5505/sakaryamj.2013.19981

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