Ankilozan Spondilitli Hastalarda Retina ve Koroid Kalınlığının Sedimentasyon Hızı ile İlişkisi

Abstract

Amaç: Sistemik olarak aktif, göz tutulumu bulunmayan Ankilozan Spondiltlilerde (AS) eritrosit sedimentasyon hızı (ESR) ile retina ve kororidal kalınlık bağlantısının araştırılması.

Gereç ve Yöntem: Romatoloji kliniğinde AS tanısı ile takip edilen, göz bölümüne konsülte edilen, göz tutulumu bulumayan kişilerile demografik olarak bunlara benzer göz kliniğinde takip edilen normal kişiler çalışmaya alındı. Kan testi sonrası göz muayenesi ve OCT ölçümü 1 saat içerisinde yapıldı. Merkezi makula kalınlığı(CMT), merkezi subfoveal koroid kalınlığı(CSCT), retina sinirlifi kalınlığı(RNFL), OCT cihazı ile ölçüldü. Çıkan sonuçlar, SPSS programı ile kontrol grubu ve AS’liler arasında ve AS’liler de kendi içinde, sedimentasyon hızına göre değerlendirildi.

Bulgular ve Sonuç: AS’li hastaların ortalama yaşı 35.8 ve ortalama hastalık süreleri 6.38 yıl idi. Ortalama ESR seviyesi 18.2 mm/H idi. Sırasıyla ortalama olarak CSCT 321.00µ, CMT 255.56µ ve RNFL 99.87µ kalınlığında idiler. Kontrol grubunda ise sırasıyla bu değerler 317.21µ, 259.02µ ve 100.98µ kalınlığında idi. CSCT, CMT ve RNFL kalınlıkları bakımından AS'liler ve normal grup arasında fark izlenmedi. AS'li hastalar ESR seviyesine göre kendi aralarında kıyaslandığında ise bu verilerin hiçbirinin ESR ile bağlantısı kurulamadı. Çalışmamızda göz tutulumu olmayan, sistemik olarak aktif AS’lilerde ESR seviyesi ile retina ve koroid kalınlık bağlantısı araştırıldı ve herhangi bir bağlantı kurulamadı.

Keywords

• ESR,AS,koroid

The Investigation of the Relationship Between Retinal and Choroidal Thickness By Sedimentation Rate for Patients with Ankylosing Spondylitis

Abstract

Objective: The investigation of the relationship between retinal and choroidal thickness with Erythrocyte Sedimentation Rate(ESR) for systematically active ankylosing spondylitis patients without ocular involvement.

 

Materials and Methods: Among the patients being followed-up with a diagnosis of AS in the rheumatology clinic, those with proper conditions who required eye consultation and normal people demographically similar to these patients being inspected in the eye section were included in the study. After blood test, eye examination and OCT measurements were performed within one hour. Central macular thickness(CMT), central subfoveal choroidal thickness(CSCT), and retinal nerve fiber layer(RNFL) thickness were measured with OCT. Results were obtained with SPSS evaluated for patients with AS compared to normal people and within the group with AS according to ESR level.

 

Results and Conclusion: The mean age of participating patients was 35.8, mean of disease duration was 6.38 years and average ESR level was 18.2mm/H. Average CSCT thickness of patients with AS was 321.00µ, average CMT thickness was 255.56µ and average RNFL thickness was 99.87µ. CSCT, CMT and RNFL thickness of control group participants were as follows: 317.21µ, 259.02µ and 100.98µ. No significant difference was observed with regard to CSCT, CMT and RNFL thickness values between patients with AS and the control group. When patients with AS were evaluated among themselves, a connection between ESR level and CSCT, CMT and RNFL thickness could not be established. In our study, we could not establish a connection between ESR level and CSCT, CMT, and RNFL.

Keywords

• ESR,AS,choroid

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