Retrospective evaluation of patients followed up in the oncology clinic.

Yıl 2015, Cilt: 5 Sayı: 2, 77 - 81, 07.09.2015

Serdar Olt Hasan Ergenç Meltem Baykara Erkan Arpacı Selçuk Yaylacı Hakan Demirci Ali Tamer

https://doi.org/10.5505/sakaryamj.2015.72687

Öz

Aim: To evaluate characteristics of the oncology patients accompanied by the current literature.Materials and Methods: We scanned archive files of 1252 cancer patients followed up in our oncology clinic between the years 2010 and 2012. We documented patients age, gender, primary tumor localization, cigarette and alcohol consumption, presence of cancer in family, presence of diabetes mellitus, presence of metastasis at the time of diagnosis, and cancer prevalence according to the gender. Results: 54.3% of the 1252 patients included in the study were female and 45.7 were male. The average age of patients were 63. 0.8% of patients were using alcohol and 30.4% of patients were smoking cigarette. Primary tumor localization ratios were; 25% breast, 18.9% lung, 12.5% colon, 8.5% rectum, 7.5% stomach, 3% ovarium, 2.1% primary unknow origin, 2% endometrium, 1.9% prostate and 1.5% pancreas respectively. The most commonly diagnosed type of cancer was breast cancer in woman and lung cancer in man.Conclusion: In our study the most common cancer types were; breast cancer, lung cancer and colon cancer respectively. We want to highlight the necessity of cancer screening programs for early diagnosis of cancer because of its poor prognosis, high mortality rates and high cost of treatment.

Anahtar Kelimeler

Cancer, epidemiology, cancer screening programs

Onkoloji kliniğinde takip ettiğimiz hastaların geriye dönük incelenmesi.

Öz

Amaç: Onkoloji kliniğimizde takip ettiğimiz hastaların özelliklerini ortaya koymak ve güncel literatür bilgileri eşliğinde yorumlamak.Gereç ve Yöntem: Onkoloji kliniğimizde 2010-2012 yılları arasında takip ettiğimiz 1252 kanser hastasının dosyaları retrospektif olarak değerlendirildi. Hastaların primer tümör lokalizasyonu, yaşı, cinsiyeti, ailede kanser öyküsü olup olmadığı, diyabetes mellitus varlığı, sigara ve alkol kullanımı, cinsiyete göre en sık görülen kanser tipleri ve tanı anında metastaz varlığı dökümante edildi. Bulgular: Çalışmaya dahil edilen 1252 hastanın 680'i (%54.3) kadın, 572'i (%45.7) erkekti. Tüm hastaların yaş ortalaması 63 idi. Hastaların 10'u (%0.8) alkol, 381'i (%30.4) sigara kullanıyordu. Ailede kanser öyküsü olan hasta sayısı 185 (%14.8) ve tanı anında diyabetik olan hasta sayısı 166 (%13,3) olarak kaydedildi. Hastaların 324'ü (%25) meme kanseri, 237'si (%18.9) akciğer kanseri, 157'si (%12.5) kolon kanseri, 107'si (%8.5) rektum kanseri, 94'ü (%7.5) mide kanseri, 38'i (%3) over kanseri, 27'si (%2.1) primeri bilinmeyen kanser, 26'sı (%2) endometrium kanseri, 24'ü (%1.9) prostat kanseri, 19'u (%1.5) pankreas kanseri, 14'ü (%1.1) testis kanseri ve 185'i (%14.7) diğer kanserler olarak saptandı. Tanı anında hastaların %41.1'inde metastaz saptandı. Erkek hastalarda en sık saptanan 3 kanser türü sırasıyla; akciğer kanseri (%35.9), kolorektal kanser (%23) ve mide kanseri (%10.8) olarak saptandı. Kadın hastalarda en sık saptanan üç kanser türü sırasıyla; meme kanseri (%46.6), kolorektal kanser (%18.4) ve akciğer kanseri (%5.2) olarak saptandı.Sonuç: Çalışmamızda tüm hastalarda en sık görülen ilk üç malignite sırasıyla; meme kanseri, akciğer kanseri ve kolon kanseri olarak tespit edildi. Evresi yüksek kanserlerde yüksek mortalite ve tedavi maliyetleri ile düşük prognoz düşünüldüğünde erken tanı açısından kanser tarama programlarının etkin bir şekilde uygulanmasının gerekliliğini vurgulamak istedik.

Anahtar Kelimeler

Kanser, epidemiyoloji, kanser tarama programları

Kaynakça

• Irwin MR. Depression and insomnia in cancer: prevalence, risk factors, and effects on cancer outcomes. Curr Psychiatry Rep. 2013 Nov;15(11):404.
• Bray F, Ren JS, Masuyer E, Ferlay J. Estimates of global cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer. 2013 Mar 1;132(5):1133-45.
• Turkiewicz D, Miller B, Schache D, ve ark. Young patients with colorectal cancer: how do they fare? Aust NZJ Surg 2001;71:707-710.
• Tárraga López PJ(1), Albero JS(2), Rodríguez-Montes JA(3). Primary and secondary prevention of colorectal cancer Clin Med Insights Gastroenterol. 2014 Jul 14;7:33-46.
• Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, et al. Cancer statistics, 2006. CA Cancer J Clin 2006;56(2):106- 30.
• Dey S. Preventing breast cancer in LMICs via screening and/ or early detection: The real and the surreal. World J Clin Oncol. 2014 Aug 10;5(3):509-19.
• Saslow D, Boetes C, Burke W, et al for the American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 2007;57:75- 89.
• Pisano ED, Gatsonis C, Hendrick E, et al. Diagnostic performance of digital versus film mammography for breast-cancer screening. N Engl J Med. 2005;353:1773- 1783.
• Saslow D, Boetes C, Burke W, et al for the American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 2007;57:75- 89.
• Smith RA, Saslow D, Sawyer KA, et al. American Cancer Society guidelines for breast cancer screening: Update 2003. CA Cancer J Clin. 2003;53:141-169.
• Park YS. Lung cancer screening: subsequent evidences of national lung screening trial. Tuberc Respir Dis (Seoul). 2014 Aug;77(2):55-9. doi: 10.4046/trd.2014.77.2.55.
• Wender R, Fontham E, Barrera E, et al. American Cancer Society lung cancer screening guidelines: CA Cancer Journal for Clinicians. 2013 Mar-Apr;63(2):107-17.
• Levin B, Lieberman DA, McFarland, et al. Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, CA Cancer J Clin. 2008;58: 130–160.
• Hawk ET, Levin B. Colorectal cancer prevention. J Clin Oncol. 2005;23:378–388.
• Hendriks YM, deJong AE, Morreau H, et al. Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): A guide for clinicians. CA Cancer J Clin. 2006;56:213-225.
• Kelloff GJ, Schilsky RL, Alberts DS, Day RW, Guyton KZ, Pearce HL, Peck JC, Phillips R, Sigman CC. Colorectal adenomas: a prototype for the use of surrogate end points in the development of cancer prevention drugs. Clin Cancer Res. 2004;10(11):3908-18.
• Kushi LH, Doyle C, McCullough M, et al. American Cancer Society Guidelines on nutrition and physical activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin. 2012 Jan-Feb;62(1):30-67.
• Levin B, Lieberman DA, McFarland, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin. 2008;58:130-160.
• Rex DK, Kaho CJ, Levin B, et al. Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and US Multi-Society Task Force on Colorectal Cancer. CA Cancer J Clin. 2006;56:160- 167.
• Winawer, SJ, Zauber AG, Fletcher RH, et al. Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. CA Cancer J Clin. 2006;56:143-159.
• Saslow D, Solomon D, Lawson H, et al. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology Screening Guidelines for the Prevention and Early Detection of Cervical Cancer. CA Cancer J Clin. 2012 May- Jun;62(3):147-72.
• Smith RA, Brooks D, Cokkinides V, Salsow D, Brawley OW. Cancer screening in the United States, 2013: A review of current American Cancer Society guidelines, current issues in cancer screening, and new guidance on cervical cancer screening and lung cancer screening. CA Cancer J Clin 2013, Mar-Apr;63:87-105.