Fertility relevant hormones in men with spinal cord injury: case control study

Yıl 2012, Cilt: 2 Sayı: 2, 71 - 76, 01.06.2012

Cevdet Serkan Gökkaya Özer Güzel N. Kutay Ordu Gökkaya Özgür Demirdal Süleyman Bulut Cüneyt Özden Halil Uçan Ali Memiş

https://doi.org/10.5505/sakaryamj.2012.75047

Öz

Objective: Individual and social effects of spinal cord injury is an important cause of morbidity. After the spinal cord injury substantial hormonal changes are seen. The aim of the study was to evaluate the fertility-related hormonal profiles and the clinic implications in men with traumatic spinal cord injury. Materials and Methods: Total of 59 patients with spinal cord injury (complete (Group 1, n = 41) and incomplete (Group 2, n = 18)) and 54 healthy volunteers (Group 3) participated in this study. Blood samples were collected for determination of FSH, LH, Prolactin, tTestosteron, sTestosteron, DHEA-S, estradiol levels of all patients and volunteers included in the study. In addition, all patients and volunteers completed IIEF (International Index of Erectile Function) questionnaire. Patients (Group 1 and Group 2) and healthy volunteers (Group 3) were compared with each other.Results: PRL levels of both SCI groups (Group 1 and Group 2), were significantly higher (p

Anahtar Kelimeler

Spinal cord injury, hormones, sexual dysfunction

Spinal kord yaralanmalı erkeklerde fertilite ilişkili hormonlar: vaka-kontrol çalışması

Öz

Amaç: Omurilik yaralanmaları bireysel ve toplumsal etkileri olan önemli bir morbidite nedenidir. Yaralanma sonrası önemli hormonal değişiklikler görülür. Çalışmamızda omurilik yaralanmalı erkek hastalarda fertilite ilişkili hormonal parametreleri ve klinik yansımalarını değerlendirdik.Gereç ve Yöntemler: Çalışmamıza komplet (Grup 1 n=41) ve inkomplet (Grup 2 n=18) spinal yaralanması olan toplam 59 hasta ile 54 sağlıklı gönüllü (Grup 3) dahil edildi. Çalışmaya dahil edilen tüm hasta ve gönüllülerden FSH, LH, Prolaktin, tTestosteron, sTestosteron, DHEA-S, Östradiol seviyelerinin tespiti için kan numuneleri alındı. Ayrıca tüm hasta ve gönüllülere İİEF (Uluslararası Ereksiyon İşlevi Değerlendirme) formu uygulandı. Hastalar (Grup 1 ve Grup 2) ile sağlıklı gönüllüler (Grup 3) ve her grup birbiri ile karşılaştırıldı.Bulgular: Hastaların tamamında (Grup 1 ve Grup 2) PRL düzeyleri kontrol grubundan (Grup 3) daha yüksekti (p

Anahtar Kelimeler

Omurilik yaralanması, hormonlar, seksüel disfonksiyon

Kaynakça

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