Larinks
kanseri en sık rastlanılan baş boyun kanseridir. En yaygın görülen tipi skuamöz
hücreli karsinomdur. Larinksin nöroendokrin tümörleri ise çok nadir (< %1)
görülür.1,8 Burada larinkste çok
nadir görülen küçük hücreli karsinom olgusu sunulacaktır.
1. Ferlito, A., Silver, C. E., Bradford, C. R. Rinaldo, A. Neuroendocrine neoplasms of the larynx: an overview. Head & neck. 2009 31(12):1634-1646.
2. Miki, K., Orita, Y., Nose, S., Hirai, M., Noyama, Y., Domae, S., et al. Neuroendocrine carcinoma of the larynx presenting as a primary unknown carcinoma. Auris Nasus Larynx. 2012 39(1): 98-102.
3. Özlük, Y. "Larinksin küçük hücreli nöroendokrin karsinomlarında TTF-1 ekspresyonu." Türk Patoloji Dergisi. 2005 21: 17-20.
4. Van der Laan, T. P., Plaat, B. E., Van der Laan, B. F., Halmos, G. B. Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta‐analysis of 436 reported cases. Head & neck. 2015 37(5): 707-715.
5. Kalai, U., Madan, K., Jain, D., Mohan, A., Guleria, R. Laryngeal metastasis from lung cancer. Lung India: official organ of Indian Chest Society.2015 32(3): 268.
6. Ferlito, A., Rinaldo, A. Primary and secondary small cell neuroendocrine carcinoma of the larynx: a review. Head & neck, 2008 30(4): 518-524.
7. Iqbal, M. S., Paleri, V., Moor, J., Dobrowsky, W., Kelly, C., Kovarik, J. Small cell neuroendocrine carcinoma of larynx: case series and literature review. The Journal of Laryngology & Otology, 2015 129(9): 910-915.
8. Baugh RF, Wolf GT, Beals TF, Krause CJ, Forastiere A. Small cell carcinoma of the larynx: results of therapy Laryngoscope. 1986 Nov; 96(11):1283-90
9. Barker, J. L., Glisson, B. S., Garden, A. S., El‐Naggar, A. K., Morrison, W. H., Ang, K. K., et al. Management of nonsinonasal neuroendocrine carcinomas of the head and neck. Cancer. 2003 98(11): 2322-2328.
10. Soga, J., Osaka, M., Yakuwa, Y. Laryngeal endocrinomas (carcinoids and relevant neoplasms): analysis of 278 reported cases. Journal of experimental & clinical cancer research: CR, 2002, 21(1):5-13.
Larynx
cancer is the most common head and neck cancer. The most common type is
squamous cell carcinoma. Neuroendocrine tumors of the larynx are very rare
(<1%).1,8 Here, a very rare case of small cell carcinoma of the
larynx will be presented.
1. Ferlito, A., Silver, C. E., Bradford, C. R. Rinaldo, A. Neuroendocrine neoplasms of the larynx: an overview. Head & neck. 2009 31(12):1634-1646.
2. Miki, K., Orita, Y., Nose, S., Hirai, M., Noyama, Y., Domae, S., et al. Neuroendocrine carcinoma of the larynx presenting as a primary unknown carcinoma. Auris Nasus Larynx. 2012 39(1): 98-102.
3. Özlük, Y. "Larinksin küçük hücreli nöroendokrin karsinomlarında TTF-1 ekspresyonu." Türk Patoloji Dergisi. 2005 21: 17-20.
4. Van der Laan, T. P., Plaat, B. E., Van der Laan, B. F., Halmos, G. B. Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta‐analysis of 436 reported cases. Head & neck. 2015 37(5): 707-715.
5. Kalai, U., Madan, K., Jain, D., Mohan, A., Guleria, R. Laryngeal metastasis from lung cancer. Lung India: official organ of Indian Chest Society.2015 32(3): 268.
6. Ferlito, A., Rinaldo, A. Primary and secondary small cell neuroendocrine carcinoma of the larynx: a review. Head & neck, 2008 30(4): 518-524.
7. Iqbal, M. S., Paleri, V., Moor, J., Dobrowsky, W., Kelly, C., Kovarik, J. Small cell neuroendocrine carcinoma of larynx: case series and literature review. The Journal of Laryngology & Otology, 2015 129(9): 910-915.
8. Baugh RF, Wolf GT, Beals TF, Krause CJ, Forastiere A. Small cell carcinoma of the larynx: results of therapy Laryngoscope. 1986 Nov; 96(11):1283-90
9. Barker, J. L., Glisson, B. S., Garden, A. S., El‐Naggar, A. K., Morrison, W. H., Ang, K. K., et al. Management of nonsinonasal neuroendocrine carcinomas of the head and neck. Cancer. 2003 98(11): 2322-2328.
10. Soga, J., Osaka, M., Yakuwa, Y. Laryngeal endocrinomas (carcinoids and relevant neoplasms): analysis of 278 reported cases. Journal of experimental & clinical cancer research: CR, 2002, 21(1):5-13.
Özçelik Korkmaz M, Genç S, Güven M. Larinksin Küçük Hücreli Karsinomu Olgu Sunumu. Sakarya Tıp Dergisi. Eylül 2018;8(3):663-668. doi:10.31832/smj.403153