Association between Epicardial Adipose Tissue Thickness and Left Ventricular Diastolic Functions

Yıl 2020, Cilt: 10 Sayı: 3, 390 - 396, 15.09.2020

Sabiye Yılmaz , Saadet Demirtas Inci , Kahraman Coşansu , Huseyin Gündüz , Harun Kılıç

https://doi.org/10.31832/smj.732042

Öz

Objective: Epicardial adipose tissue (EAT) has been found to be associated
with the diastolic dysfunction in recent years, but this relationship has not
been fully elucidated. Echocardiography is a non-invasive, simple, cost
effective and accessible approach to assess EAT thickness, which can be performed easily.
The aim of this study was to evaluate the effectiveness of EAT on prediction of
diastolic dysfunction.

Materials
and Methods: A total of 138
patients without any cardiovascular,
inflammatory, autoimmune and cancer disease, were enrolled. Our study was performed in the Cardiology clinic of
Sakarya University Training and Research Hospital between May 2019 and December
2019. Subjects were divided into two groups, those with and without
diastolic dysfunctions. Conventional echocardiography parameters
and tissue Doppler imaging (TDI) were performed to evaluate left ventricular
functions. EAT thickness on the free wall
of the right ventricle in parasternal long-axis view were measured using
transthoracic echocardiography.

Results: In
comparison with the non- diastolic
dysfunction group, patients with diastolic dysfunction had
significantly higher epicardial fat thickness (5.98±1.52 mm vs 4.32±1.03 mm; p<0.001).
The multivariate regression analysis indicated that EAT independently predicts diastolic dysfunction (OR, 0.278, 95%CI
0.396 to 1.400)

Conclusions:
According to the findings of this study, EAT thickness is an independent
predictor for the development of diastolic
dysfunction in patients without cardiovascular disease.

Anahtar Kelimeler

adipose tissue, echocardiography, epicardium, left ventricular function

Kaynakça

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