Araştırma Makalesi
BibTex RIS Kaynak Göster

Sağ Ventrikül Fonksiyonunun Kardiyovasküler Cerrahide Mortalite ve Reoperasyon Oranları Üzerindeki Etkisi

Yıl 2024, Cilt: 14 Sayı: 4, 388 - 397, 31.12.2024
https://doi.org/10.31832/smj.1563340

Öz

Amaç: Bu çalışmada, triküspit kapak cerrahisi geçiren hastalarda preoperatif sağ ventrikül (SV) fonksiyonunun mortalite, reoperasyon ve diğer postoperatif sonuçlar üzerindeki etkisinin araştırılması amaçlandı.
Yöntemler: Retrospektif olarak gerçekleştirilen bu çalışmada, triküspit kapak cerrahisi geçiren 100 hasta incelendi. Hastalar, preoperatif SV fonksiyonlarına göre normal, hafif depresif, orta depresif ve ciddi depresif olmak üzere dört gruba ayrıldı. Sağ ventrikül fonksiyonu ekokardiyografik parametrelerle değerlendirildi ve postoperatif mortalite, morbidite, reoperasyon gereksinimi ve ek işlem oranları, cinsiyet ve yaş gibi demografik veriler analiz edildi.
Bulgular: Ciddi depresif SV fonksiyonuna sahip hastalarda mortalite oranları anlamlı derecede yüksek bulundu (p<0.001). Reoperasyon ve ek işlem oranları da SV fonksiyonundaki bozulma ile artış gösterdi (p<0.05). Cerrahi türü (sternotomi veya torakotomi) açısından gruplar arasında anlamlı bir fark bulunamadı (p=0.714).
Sonuç: Sağ ventrikül disfonksiyonu, triküspit kapak cerrahisi geçiren hastalarda postoperatif mortalite ve reoperasyon oranlarını önemli ölçüde artırmaktadır. Preoperatif SV fonksiyonunun dikkatli bir şekilde değerlendirilmesi, cerrahi sonuçların iyileştirilmesinde kritik öneme sahiptir.

Kaynakça

  • Ren B, Spitzer E, Geleijnse ML, et al. Right ventricular systolic function in patients undergoing transcatheter aortic valve implantation: A systematic review and meta-analysis. International journal of cardiology. Apr 15 2018;257:40-45. doi:10.1016/j.ijcard.2018.01.117
  • Anastasiou V, Papazoglou AS, Moysidis DV, et al. The prognostic value of right ventricular longitudinal strain in heart failure: A systematic review and meta-analysis. Nov 2023;28(6):1383-1394. doi:10.1007/s10741-023-10329-y
  • Hameed A, Condliffe R, Swift AJ, Alabed S, Kiely DG, Charalampopoulos A. Assessment of Right Ventricular Function-a State of the Art. Current heart failure reports. Jun 2023;20(3):194-207. doi:10.1007/s11897-023-00600-6
  • Edward J, Banchs J, Parker H, Cornwell W. Right ventricular function across the spectrum of health and disease. Feb 14 2023;109(5):349-355. doi:10.1136/heartjnl-2021-320526
  • Hamandi M, George TJ, Smith RL, Mack MJ. Current outcomes of tricuspid valve surgery. Progress in cardiovascular diseases. Nov-Dec 2019;62(6):463-466. doi:10.1016/j.pcad.2019.11.014
  • Pfannmueller B, Misfeld M, Haensig M, Davierwala P, Mohr FW. Tricuspid Valve Repair after Previous Mitral Valve Surgery. The Thoracic and cardiovascular surgeon. Dec 2017;65(8):601-605. doi:10.1055/s-0037-1605362
  • Brener MI, Lurz P, Hausleiter J, et al. Right Ventricular-Pulmonary Arterial Coupling and Afterload Reserve in Patients Undergoing Transcatheter Tricuspid Valve Repair. Journal of the American College of Cardiology. Feb 8 2022;79(5):448-461. doi:10.1016/j.jacc.2021.11.031
  • Galloo X, Meucci MC, Stassen J, et al. Right Ventricular Reverse Remodeling After Tricuspid Valve Surgery for Significant Tricuspid Regurgitation. Structural heart: The journal of the Heart Team. Jan 2023;7(1):100101. doi:10.1016/j.shj.2022.100101
  • Davidson LJ, Tang GHL, Ho EC, et al. The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association. Circulation. May 28 2024;149(22):e1223-e1238. doi:10.1161/cir.0000000000001232
  • Bellofiore A, Chesler NC. Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature. Annals of biomedical engineering. Jul 2013;41(7):1384-98. doi:10.1007/s10439-013-0752-3
  • Lam PH, Keramida K, Filippatos GS, et al. Right Ventricular Ejection Fraction and Beta-Blocker Effect in Heart Failure With Reduced Ejection Fraction. Journal of cardiac failure. Jan 2022;28(1):65-70. doi:10.1016/j.cardfail.2021.07.026
  • Samarai D, Ingemansson SL, Gustafsson R, Thilén U, Hlebowicz J. Global longitudinal strain correlates to systemic right ventricular function. Cardiovascular ultrasound. Jan 27 2020;18(1):4. doi:10.1186/s12947-020-0186-7
  • Nagueh SF. Left Ventricular Diastolic Function: Understanding Pathophysiology, Diagnosis, and Prognosis With Echocardiography. JACC Cardiovascular imaging. Jan 2020;13(1 Pt 2):228-244. doi:10.1016/j.jcmg.2018.10.038
  • Altmayer S, Nazarian S, Han Y. Left Ventricular Dysfunction in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): Can We Separate ARVC From Other Arrhythmogenic Cardiomyopathies? Journal of the American Heart Association. Dec 2020;9(23):e018866. doi:10.1161/jaha.120.018866
  • Tello K, Wan J, Dalmer A, et al. Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension. Circulation Cardiovascular imaging. Sep 2019;12(9):e009047. doi:10.1161/circimaging.119.009047
  • Petersen J, Reichenspurner H, Pecha S. Atrial fibrillation surgery with a focus on patients with reduced left ventricular function and heart failure. Europace : European pacing, arrhythmias, and cardiac electrophysiology: Journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. Apr 1 2020;22(4):517-521. doi:10.1093/europace/euaa016
  • Lanspa MJ, Cirulis MM, Wiley BM, et al. Right Ventricular Dysfunction in Early Sepsis and Septic Shock. Chest. Mar 2021;159(3):1055-1063. doi:10.1016/j.chest.2020.09.274
  • Jussli-Melchers J, Scheewe J, Hansen JH, et al. Right ventricular outflow tract reconstruction with the Labcor® stentless valved pulmonary conduit. European journal of cardio-thoracic surgery: Official journal of the European Association for Cardio-thoracic Surgery. Feb 1 2020;57(2):380-387. doi:10.1093/ejcts/ezz200
  • William V, El Kilany W. Assessment of right ventricular function by echocardiography in patients with chronic heart failure. The Egyptian heart journal : (EHJ): Official bulletin of the Egyptian Society of Cardiology. Sep 2018;70(3):173-179. doi:10.1016/j.ehj.2018.04.009
  • Awad EML, Mahmoud AH, Maghrby KS, Taha NM, Ibrahim AM. Short-term prognostic value of TAPSE, RVFAC and Tricuspid S' wave peak systolic velocity after first acute myocardial infarction. BMC research notes. Apr 1 2020;13(1):196. doi:10.1186/s13104-020-05040-2
  • Sanchez PA, O'Donnell CT, Francisco N, Santana EJ. Right Ventricular Dysfunction Patterns among Patients with COVID-19 in the Intensive Care Unit: A Retrospective Cohort Analysis. Oct 2023;20(10):1465-1474. doi:10.1513/AnnalsATS.202303-235OC
  • Kant S, Banerjee D, Sabe SA, Sellke F, Feng J. Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction. Frontiers in medicine. 2023;10:1110532. doi:10.3389/fmed.2023.1110532
  • Mattei A, Strumia A, Benedetto M. Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery. Nov 17 2023;12(22)doi:10.3390/jcm12227152
  • Varma PK, Srimurugan B, Jose RL, Krishna N, Valooran GJ, Jayant A. Perioperative right ventricular function and dysfunction in adult cardiac surgery-focused review (part 2-management of right ventricular failure). Indian journal of thoracic and cardiovascular surgery. Mar 2022;38(2):157-166. doi:10.1007/s12055-021-01226-w
  • Kunigo T, Yoshikawa Y, Yamamoto S, Yamakage M. Preoperative right ventricular dysfunction requires high vasoactive and inotropic support during off-pump coronary artery bypass grafting. General thoracic and cardiovascular surgery. Jun 2021;69(6):934-942. doi:10.1007/s11748-020-01557-2
  • Merlo A, Cirelli C, Vizzardi E. Right Ventricular Dysfunction before and after Cardiac Surgery: Prognostic Implications. Mar 11 2024;13(6)doi:10.3390/jcm13061609
  • Scudiero F, Silverio A. Long-Term Prognostic Impact of Right Ventricular Dysfunction in Patients with COVID-19. Jan 26 2022;12(2)doi:10.3390/jpm12020162

Impact of Right Ventricular Function on Mortality and Reoperation Rates in Cardiovascular Surgery

Yıl 2024, Cilt: 14 Sayı: 4, 388 - 397, 31.12.2024
https://doi.org/10.31832/smj.1563340

Öz

Objective: This study aimed to investigate the impact of preoperative right ventricular (RV) function on postoperative outcomes such as mortality, reoperation rates, valve size, and other clinical variables in patients undergoing tricuspid valve surgery.
Methods: This retrospective study included 100 patients who underwent tricuspid valve surgery. Patients were categorized into four groups based on preoperative RV function: normal, mildly depressed, moderately depressed, and severely depressed. RV function was assessed using echocardiographic parameters, including tricuspid annular plane systolic excursion (TAPSE), tissue Doppler imaging (TDI), mean pulmonary artery pressure (MPAB), and valve size. Postoperative outcomes, including mortality and reoperation rates, were analyzed.
Results: Patients with severely depressed RV function had significantly higher mortality rates (p=0.035). Reoperation rates also increased as RV function worsened (p=0.006). No significant difference was found between groups regarding valve size (p>0.05) or the type of surgery (sternotomy or thoracotomy) (p=0.714).
Conclusion: Right ventricular dysfunction significantly increases postoperative mortality and reoperation rates in patients undergoing tricuspid valve surgery. Careful preoperative evaluation of RV function, including valve size, is critical for improving surgical outcomes.

Etik Beyan

This study received ethical approval from the 1nd Clinical Research Ethics Committee of Ankara Bilkent City Hospital on 07.06.2023, with decision number TABED-1-24-529. The study, was reviewed and unanimously approved in terms of ethical considerations.

Destekleyen Kurum

Not applicable.

Teşekkür

Not applicable.

Kaynakça

  • Ren B, Spitzer E, Geleijnse ML, et al. Right ventricular systolic function in patients undergoing transcatheter aortic valve implantation: A systematic review and meta-analysis. International journal of cardiology. Apr 15 2018;257:40-45. doi:10.1016/j.ijcard.2018.01.117
  • Anastasiou V, Papazoglou AS, Moysidis DV, et al. The prognostic value of right ventricular longitudinal strain in heart failure: A systematic review and meta-analysis. Nov 2023;28(6):1383-1394. doi:10.1007/s10741-023-10329-y
  • Hameed A, Condliffe R, Swift AJ, Alabed S, Kiely DG, Charalampopoulos A. Assessment of Right Ventricular Function-a State of the Art. Current heart failure reports. Jun 2023;20(3):194-207. doi:10.1007/s11897-023-00600-6
  • Edward J, Banchs J, Parker H, Cornwell W. Right ventricular function across the spectrum of health and disease. Feb 14 2023;109(5):349-355. doi:10.1136/heartjnl-2021-320526
  • Hamandi M, George TJ, Smith RL, Mack MJ. Current outcomes of tricuspid valve surgery. Progress in cardiovascular diseases. Nov-Dec 2019;62(6):463-466. doi:10.1016/j.pcad.2019.11.014
  • Pfannmueller B, Misfeld M, Haensig M, Davierwala P, Mohr FW. Tricuspid Valve Repair after Previous Mitral Valve Surgery. The Thoracic and cardiovascular surgeon. Dec 2017;65(8):601-605. doi:10.1055/s-0037-1605362
  • Brener MI, Lurz P, Hausleiter J, et al. Right Ventricular-Pulmonary Arterial Coupling and Afterload Reserve in Patients Undergoing Transcatheter Tricuspid Valve Repair. Journal of the American College of Cardiology. Feb 8 2022;79(5):448-461. doi:10.1016/j.jacc.2021.11.031
  • Galloo X, Meucci MC, Stassen J, et al. Right Ventricular Reverse Remodeling After Tricuspid Valve Surgery for Significant Tricuspid Regurgitation. Structural heart: The journal of the Heart Team. Jan 2023;7(1):100101. doi:10.1016/j.shj.2022.100101
  • Davidson LJ, Tang GHL, Ho EC, et al. The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association. Circulation. May 28 2024;149(22):e1223-e1238. doi:10.1161/cir.0000000000001232
  • Bellofiore A, Chesler NC. Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature. Annals of biomedical engineering. Jul 2013;41(7):1384-98. doi:10.1007/s10439-013-0752-3
  • Lam PH, Keramida K, Filippatos GS, et al. Right Ventricular Ejection Fraction and Beta-Blocker Effect in Heart Failure With Reduced Ejection Fraction. Journal of cardiac failure. Jan 2022;28(1):65-70. doi:10.1016/j.cardfail.2021.07.026
  • Samarai D, Ingemansson SL, Gustafsson R, Thilén U, Hlebowicz J. Global longitudinal strain correlates to systemic right ventricular function. Cardiovascular ultrasound. Jan 27 2020;18(1):4. doi:10.1186/s12947-020-0186-7
  • Nagueh SF. Left Ventricular Diastolic Function: Understanding Pathophysiology, Diagnosis, and Prognosis With Echocardiography. JACC Cardiovascular imaging. Jan 2020;13(1 Pt 2):228-244. doi:10.1016/j.jcmg.2018.10.038
  • Altmayer S, Nazarian S, Han Y. Left Ventricular Dysfunction in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): Can We Separate ARVC From Other Arrhythmogenic Cardiomyopathies? Journal of the American Heart Association. Dec 2020;9(23):e018866. doi:10.1161/jaha.120.018866
  • Tello K, Wan J, Dalmer A, et al. Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension. Circulation Cardiovascular imaging. Sep 2019;12(9):e009047. doi:10.1161/circimaging.119.009047
  • Petersen J, Reichenspurner H, Pecha S. Atrial fibrillation surgery with a focus on patients with reduced left ventricular function and heart failure. Europace : European pacing, arrhythmias, and cardiac electrophysiology: Journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. Apr 1 2020;22(4):517-521. doi:10.1093/europace/euaa016
  • Lanspa MJ, Cirulis MM, Wiley BM, et al. Right Ventricular Dysfunction in Early Sepsis and Septic Shock. Chest. Mar 2021;159(3):1055-1063. doi:10.1016/j.chest.2020.09.274
  • Jussli-Melchers J, Scheewe J, Hansen JH, et al. Right ventricular outflow tract reconstruction with the Labcor® stentless valved pulmonary conduit. European journal of cardio-thoracic surgery: Official journal of the European Association for Cardio-thoracic Surgery. Feb 1 2020;57(2):380-387. doi:10.1093/ejcts/ezz200
  • William V, El Kilany W. Assessment of right ventricular function by echocardiography in patients with chronic heart failure. The Egyptian heart journal : (EHJ): Official bulletin of the Egyptian Society of Cardiology. Sep 2018;70(3):173-179. doi:10.1016/j.ehj.2018.04.009
  • Awad EML, Mahmoud AH, Maghrby KS, Taha NM, Ibrahim AM. Short-term prognostic value of TAPSE, RVFAC and Tricuspid S' wave peak systolic velocity after first acute myocardial infarction. BMC research notes. Apr 1 2020;13(1):196. doi:10.1186/s13104-020-05040-2
  • Sanchez PA, O'Donnell CT, Francisco N, Santana EJ. Right Ventricular Dysfunction Patterns among Patients with COVID-19 in the Intensive Care Unit: A Retrospective Cohort Analysis. Oct 2023;20(10):1465-1474. doi:10.1513/AnnalsATS.202303-235OC
  • Kant S, Banerjee D, Sabe SA, Sellke F, Feng J. Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction. Frontiers in medicine. 2023;10:1110532. doi:10.3389/fmed.2023.1110532
  • Mattei A, Strumia A, Benedetto M. Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery. Nov 17 2023;12(22)doi:10.3390/jcm12227152
  • Varma PK, Srimurugan B, Jose RL, Krishna N, Valooran GJ, Jayant A. Perioperative right ventricular function and dysfunction in adult cardiac surgery-focused review (part 2-management of right ventricular failure). Indian journal of thoracic and cardiovascular surgery. Mar 2022;38(2):157-166. doi:10.1007/s12055-021-01226-w
  • Kunigo T, Yoshikawa Y, Yamamoto S, Yamakage M. Preoperative right ventricular dysfunction requires high vasoactive and inotropic support during off-pump coronary artery bypass grafting. General thoracic and cardiovascular surgery. Jun 2021;69(6):934-942. doi:10.1007/s11748-020-01557-2
  • Merlo A, Cirelli C, Vizzardi E. Right Ventricular Dysfunction before and after Cardiac Surgery: Prognostic Implications. Mar 11 2024;13(6)doi:10.3390/jcm13061609
  • Scudiero F, Silverio A. Long-Term Prognostic Impact of Right Ventricular Dysfunction in Patients with COVID-19. Jan 26 2022;12(2)doi:10.3390/jpm12020162
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kalp ve Damar Cerrahisi
Bölüm Araştırma Makalesi
Yazarlar

Muhammet Fethi Sağlam 0000-0003-0744-0001

Emrah Uğuz Bu kişi benim 0000-0002-2758-7644

Kemal Erdoğan 0000-0002-2684-7256

Hüseyin Ünsal Erçelik Bu kişi benim 0000-0001-5253-2525

Murat Yücel 0000-0002-9182-0690

Mete Hıdıroğlu 0000-0001-7235-9432

Erol Sener 0000-0002-8295-7249

Erken Görünüm Tarihi 30 Aralık 2024
Yayımlanma Tarihi 31 Aralık 2024
Gönderilme Tarihi 8 Ekim 2024
Kabul Tarihi 16 Aralık 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 14 Sayı: 4

Kaynak Göster

AMA Sağlam MF, Uğuz E, Erdoğan K, Erçelik HÜ, Yücel M, Hıdıroğlu M, Sener E. Impact of Right Ventricular Function on Mortality and Reoperation Rates in Cardiovascular Surgery. Sakarya Tıp Dergisi. Aralık 2024;14(4):388-397. doi:10.31832/smj.1563340

30703

SMJ'de yayınlanan makaleler, Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı kapsamında lisanslanır