DÜZENLİ EGZERSİZ YAPAN OBEZ VE FAZLA KİLOLU BİREYLERDE D VİTAMİNİ REPLASMANININ KİLO KAYBI VE ANTİOKSİDAN DENGE ÜZERİNE ETKİSİNİN DEĞERLENDİRİLMESİ

Öz

Obezite ve egzersizin, metabolik süreçler ve O2 kullanımının orantısal artışı sonucunda serbest radikal oluşumunu ve oksidatif stresi artırdığı vurgulanmaktadır. Çalışmamızda düzenli egzersiz yapan, Beden Kütle İndeksi (BKİ)≥25 kg/m2 bireylerde D vitamini takviyesinin kilo kaybı ve antioksidan denge üzerine etkisini araştırmak amaçlanmıştır. Kayseri’de bir spor salonuna kayıtlı, düzenli egzersiz yapan, D vitamini yetersizliği saptanmış (serum 25(OH)D<30 ng/ml) 44 gönüllü, çalışma (n=26) ve kontrol (n=18) grubu olmak üzere ikiye ayrılmıştır. Çalışma grubundaki bireylere 3 ay süresince, ayda bir defa 300.000 IU/ml D3 içeren D vitamini ampulü oral yoldan verilmiş; kontrol grubundaki bireylere ise herhangi bir replasman uygulanmamıştır. Araştırma sonucunda, çalışma grubunun total antioksidan seviyesinde (TAS) istatistiksel olarak anlamlı olmayan bir artış; total oksidan seviyelerinde (TOS) ise istatistiksel olarak anlamlı düzeyde düşüş gözlemlenmiştir. Kontrol grubunda, serum 25(OH)D ve TAS seviyelerinde anlamlı düzeyde azalma; TOS seviyesinde ise anlamlı olmayan bir artış saptanmıştır. Ayrıca serum 25(OH)D seviyesi ile BKİ ve vücut yağ oranı arasında anlamlı negatif korelasyon; TAS seviyesi arasında ise anlamlı düzeyde pozitif korelasyon saptanmıştır. Sonuç olarak, düzenli spor yapan kişilerde D vitamini replasmanının, kilo kaybı üzerinde anlamlı bir etkisi olmamakla birlikte bireylerin antioksidan dengesi üzerinde olumlu etki gösterdiği gözlemlenmiştir.

Anahtar Kelimeler

• D vitamini
• Obezite
• Egzersiz
• Oksidatif stres
• Kilo kaybı

EVALUATION OF THE EFFECT OF VITAMIN D REPLACEMENT ON WEIGHT LOSS AND ANTIOXIDANT BALANCE IN OBESE AND OVERWEIGHT INDIVIDUALS WHO EXERCISE REGULARLY

Abstract

It is emphasized that obesity and exercise increase free radical formation and oxidative stress as a result of the proportional increase in metabolic processes and O2 use. In our study, it was aimed to investigate the effects of vitamin D replacement on weight loss and antioxidant balance in individuals with a Body Mass Index (BMI)≥25 kg/m2 who exercise regularly. 44 volunteers registered in a gym in Kayseri, exercising regularly, and confirmed to have vitamin D deficiency (serum 25(OH)D<30 ng/ml) were divided into two groups as study (n=26) and control (n=18) groups. Vitamin D ampoules containing 300,000 IU/ml D3 was given orally once a month to the individuals in the study group for 3 months, the individuals in the control group did not receive any replacement. As a result of the research, it was observed a statistically non-significant increase in the total antioxidant level (TAS) of the study group; a statistically significant decrease in total oxidant levels (TOS). In the control group, it was found a significant decrease in serum 25(OH)D and TAS levels; a non-significant increase in the TOS level. In addition, there was a significant negative correlation between serum 25(OH)D level and BMI and body fat ratio; a significant positive correlation was found between TAS level. As a result, it was observed that vitamin D replacement did not have a significant effect on weight loss in people who regularly exercise, but had a positive effect on the antioxidant balance of individuals.

Keywords

• Vitamin D
• Obesity
• Exercise
• Oxidative stress
• Weight loss

Kaynakça

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