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AUDIOLOGIC FINDINGS IN PARKINSON'S DISEASE

Yıl 2025, Cilt: 6 Sayı: 1, 190 - 200, 28.02.2025
https://doi.org/10.70813/ssd.1598913

Öz

Purpose: This study aimed to describe the audiologic findings of individuals with Parkinson's Disease and investigate the relationship between hearing impairments and the disease.
Methods: Thirty-nine individuals aged 47-80 with idiopathic Parkinson's Disease were included as the study group, and 20 individuals aged 48-78 without neurological disorder were included as the control group. 0,125-8 kHz pure tone audiometry, speech audiometry, the standardized Mini-Mental test, tympanometry, and the ipsilateral acoustic reflex test were performed by applying descriptive statistics or comparing groups.
Results: There were no significant differences between the study and control groups for pure tone mean, speech recognition threshold, speech discrimination score, and most comfortable hearing level between the right and left ears and between the groups (p≥0.005). Acoustic reflex thresholds of 0,5-2 kHz in 21 individuals and 4 kHz in 18 individuals in the study group; acoustic reflex thresholds of 0,5-2 kHz in 15 individuals and 4 kHz in 14 individuals in the control group. According to the data obtained, there was no statistically significant difference between the two groups regarding acoustic reflex thresholds obtained in the 0,5-4 kHz range (p≥0.005).
Conclusion: There was no difference between the study group and the control group in terms of pure tone average, 0,125-8 kHz air conduction and 0,5-4 kHz bone conduction hearing thresholds, speech recognition threshold, speech discrimination score, most comfortable hearing level, and ipsilateral acoustic reflex results for the right and left ears. However, the thresholds were higher in individuals diagnosed with Parkinson's disease, especially in 6 and 8 kHz hearing thresholds.

Kaynakça

  • Balestrino, R., & Schapira, A. (2020). Parkinson disease. European journal of neurology, 27(1), 27-42.
  • Braak, H., Ghebremedhin, E., Rüb, U., Bratzke, H., & Del Tredici, K. (2004). Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res, 318(1), 121-134. https://doi.org/10.1007/s00441-004-0956-9
  • Daroff, R. B., Fenichel, G. M., Jankovic, J., & Mazziotta, J. C. (2012). Neurology in clinical practice. Elsevier Health Sciences.
  • Folmer, R. L., Vachhani, J., Theodoroff, S. M., Ellinger, R., & Riggins, A. (2017). Auditory Processing Abilities of Parkinson’s Disease Patients. Biomed Research International, 2017, 1-10. https://doi.org/10.1155/2017/2618587
  • Folmer, R. L., Vachhani, J. J., Theodoroff, S. M., Ellinger, R., & Riggins, A. (2017). Auditory Processing Abilities of Parkinson's Disease Patients. Biomed Res Int, 2017, 2618587. https://doi.org/10.1155/2017/2618587
  • Gillies, G. E., Pienaar, I. S., Vohra, S., & Qamhawi, Z. (2014). Sex differences in Parkinson’s disease. Frontiers in neuroendocrinology, 35(3), 370-384.
  • Goossens, T., Vercammen, C., Wouters, J., & van Wieringen, A. (2017). Masked speech perception across the adult lifespan: Impact of age and hearing impairment. Hear Res, 344, 109-124. https://doi.org/10.1016/j.heares.2016.11.004
  • Gökay, N. Y., Gündüz, B., Söke, F., & Karamert, R. (2021). Evaluation of Efferent Auditory System and Hearing Quality in Parkinson's Disease: Is the Difficulty in Speech Understanding in Complex Listening Conditions Related to Neural Degeneration or Aging? J Speech Lang Hear Res, 64(1), 263-271. https://doi.org/10.1044/2020_jslhr-20-00337
  • Güngen, C., Ertan, T., Eker, E., Yaşar, R., & Engin, F. (2002). Standardize mini mental test’in Türk toplumunda hafif demans tan› s› nda geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi, 13(4), 273-281.
  • Jankovic, J. (2008). Parkinson’s disease: clinical features and diagnosis. Journal of neurology, neurosurgery & psychiatry, 79(4), 368-376.
  • Lai, S. W., Liao, K. F., Lin, C. L., Lin, C. L., & Sung, F. C. (2014). Hearing Loss May Be a Non‐motor Feature of Parkinson's disease in older people in Taiwan. European journal of neurology, 21(5), 752-757. https://doi.org/10.1111/ene.12378
  • Lee, A., & Gilbert, R. M. (2016). Epidemiology of Parkinson disease. Neurologic clinics, 34(4), 955-965.
  • Molloy, D. (2014). Standardised Mini-Mental State Examination (SMMSE)-Guidelines for administration and scoring instructions. Am J Psychiatry, 14, 102-105.
  • Pisani, V., Sisto, R., Moleti, A., Di Mauro, R., Pisani, A., Brusa, L., . . . Di Girolamo, S. (2015). An investigation of hearing impairment in de-novo Parkinson's disease patients: A preliminary study. Parkinsonism Relat Disord, 21(8), 987-991. https://doi.org/10.1016/j.parkreldis.2015.06.007
  • Poling, G. L., Kunnel, T. J., & Dhar, S. (2016). Comparing the Accuracy and Speed of Manual and Tracking Methods of Measuring Hearing Thresholds. Ear Hear, 37(5), e336-340. https://doi.org/10.1097/aud.0000000000000317
  • Rabelo, M. B., Lopes, M. d. S., Corona, A. P., Araújo, R. P. C. d., & Nóbrega, A. C. (2018). Hearing Handicap Perception and Hearing Alterations in Individuals With Parkinson's Disease. Revista Cefac, 20(2), 135-144. https://doi.org/10.1590/1982-0216201820213117
  • Shetty, K., Krishnan, S., Thulaseedharan, J. V., Mohan, M., & Kishore, A. (2019). Asymptomatic Hearing Impairment Frequently Occurs in Early-Onset Parkinson's Disease. J Mov Disord, 12(2), 84-90. https://doi.org/10.14802/jmd.18048 Uluyol, S., Kilicaslan, S., Baydar, C., & ŞENER, U. (2016). Hearing impairment and tinnitus severity in Parkinson’s disease. Turkish Journal of Geriatrics/Türk Geriatri Dergisi, 19(4). Vitale, C., Marcelli, V., Abate, T., Pianese, A., Allocca, R., Moccia, M., . . . Cavaliere, M. (2016). Speech discrimination is impaired in parkinsonian patients: Expanding the audiologic findings of Parkinson's disease. Parkinsonism Relat Disord, 22 Suppl 1, S138-143. https://doi.org/10.1016/j.parkreldis.2015.09.040 Vitale, C., Marcelli, V., Allocca, R., Santangelo, G., Riccardi, P., Erro, R., . . . Barone, P. (2012). Hearing Impairment in Parkinson's Disease: Expanding the Nonmotor Phenotype. Movement Disorders, 27(12), 1530-1535. https://doi.org/10.1002/mds.25149

PARKİNSON HASTALIĞINDA ODYOLOJİK BULGULAR

Yıl 2025, Cilt: 6 Sayı: 1, 190 - 200, 28.02.2025
https://doi.org/10.70813/ssd.1598913

Öz

Amaç: Bu çalışmanın amacı Parkinson Hastalığı olan bireylerin odyolojik bulgularını tanımlamak ve işitme bozuklukları ile hastalık arasındaki ilişkiyi araştırmaktır.
Yöntem: Araştırmaya idiopatik Parkinson Hastalığı tanısı almış 47-80 yaş aralığında 39 birey çalışma grubu olarak ve herhangi bir nörolojik bozukluğu olmayan 48-78 yaş aralığında 20 birey kontrol grubu olarak çalışmaya dahil edilmiştir. Bu katılımcılara 0,125-8 kHz saf ses odyometri, konuşma odyometrisi, standardize Mini Mental test, timpanometri ve ipsilateral akustik refleks testi uygulanarak tanımlayıcı istatistikler verilmiş veya gruplar arası karşılaştırmalar yapılmıştır.
Bulgular: Çalışma ve kontrol grupları için sağ ve sol kulak arasında ve gruplar arasında saf ses ortalaması, konuşmayı tanıma eşiği, konuşmayı ayırt etme skoru ve en rahat duyma seviyesi sonuçları için anlamlı farklılık bulunamamıştır (p≥0,005). Çalışma grubunda 21 katılımcıda 0,5-2 kHz, 18 katılımcıda 4 kHz akustik refleks eşikleri; kontrol grubunda 15 katılımcıda 0,5-2 kHz, 14 katılımcıda 4 kHz akustik refleks eşikleri elde edilmiştir. Elde edilen verilere göre iki grup arasında 0,5-4 Hz aralığında elde edilen akustik refleks eşikleri açısından da istatistiksel olarak anlamlı farklılık bulunmamıştır (p≥0,005).
Sonuç: Çalışma grubu ile kontrol grubu arasında sağ ve sol kulak için saf ses ortalaması, 0,125-8 kHz hava yolu, 0,5-4 kHz kemik yolu işitme eşikleri, konuşmayı tanıma eşiği, konuşmayı ayırt etme skoru, en rahat duyma seviyesi ve ipsilateral akustik refleks sonuçları açısından farklılık tespit edilememiştir. Ancak, özellikle 6 ve 8 kHz frekans işitme eşiklerinde Parkinson tanılı bireylerde eşiklerin daha yüksek olduğu ifade edilebilmektedir.

Kaynakça

  • Balestrino, R., & Schapira, A. (2020). Parkinson disease. European journal of neurology, 27(1), 27-42.
  • Braak, H., Ghebremedhin, E., Rüb, U., Bratzke, H., & Del Tredici, K. (2004). Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res, 318(1), 121-134. https://doi.org/10.1007/s00441-004-0956-9
  • Daroff, R. B., Fenichel, G. M., Jankovic, J., & Mazziotta, J. C. (2012). Neurology in clinical practice. Elsevier Health Sciences.
  • Folmer, R. L., Vachhani, J., Theodoroff, S. M., Ellinger, R., & Riggins, A. (2017). Auditory Processing Abilities of Parkinson’s Disease Patients. Biomed Research International, 2017, 1-10. https://doi.org/10.1155/2017/2618587
  • Folmer, R. L., Vachhani, J. J., Theodoroff, S. M., Ellinger, R., & Riggins, A. (2017). Auditory Processing Abilities of Parkinson's Disease Patients. Biomed Res Int, 2017, 2618587. https://doi.org/10.1155/2017/2618587
  • Gillies, G. E., Pienaar, I. S., Vohra, S., & Qamhawi, Z. (2014). Sex differences in Parkinson’s disease. Frontiers in neuroendocrinology, 35(3), 370-384.
  • Goossens, T., Vercammen, C., Wouters, J., & van Wieringen, A. (2017). Masked speech perception across the adult lifespan: Impact of age and hearing impairment. Hear Res, 344, 109-124. https://doi.org/10.1016/j.heares.2016.11.004
  • Gökay, N. Y., Gündüz, B., Söke, F., & Karamert, R. (2021). Evaluation of Efferent Auditory System and Hearing Quality in Parkinson's Disease: Is the Difficulty in Speech Understanding in Complex Listening Conditions Related to Neural Degeneration or Aging? J Speech Lang Hear Res, 64(1), 263-271. https://doi.org/10.1044/2020_jslhr-20-00337
  • Güngen, C., Ertan, T., Eker, E., Yaşar, R., & Engin, F. (2002). Standardize mini mental test’in Türk toplumunda hafif demans tan› s› nda geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi, 13(4), 273-281.
  • Jankovic, J. (2008). Parkinson’s disease: clinical features and diagnosis. Journal of neurology, neurosurgery & psychiatry, 79(4), 368-376.
  • Lai, S. W., Liao, K. F., Lin, C. L., Lin, C. L., & Sung, F. C. (2014). Hearing Loss May Be a Non‐motor Feature of Parkinson's disease in older people in Taiwan. European journal of neurology, 21(5), 752-757. https://doi.org/10.1111/ene.12378
  • Lee, A., & Gilbert, R. M. (2016). Epidemiology of Parkinson disease. Neurologic clinics, 34(4), 955-965.
  • Molloy, D. (2014). Standardised Mini-Mental State Examination (SMMSE)-Guidelines for administration and scoring instructions. Am J Psychiatry, 14, 102-105.
  • Pisani, V., Sisto, R., Moleti, A., Di Mauro, R., Pisani, A., Brusa, L., . . . Di Girolamo, S. (2015). An investigation of hearing impairment in de-novo Parkinson's disease patients: A preliminary study. Parkinsonism Relat Disord, 21(8), 987-991. https://doi.org/10.1016/j.parkreldis.2015.06.007
  • Poling, G. L., Kunnel, T. J., & Dhar, S. (2016). Comparing the Accuracy and Speed of Manual and Tracking Methods of Measuring Hearing Thresholds. Ear Hear, 37(5), e336-340. https://doi.org/10.1097/aud.0000000000000317
  • Rabelo, M. B., Lopes, M. d. S., Corona, A. P., Araújo, R. P. C. d., & Nóbrega, A. C. (2018). Hearing Handicap Perception and Hearing Alterations in Individuals With Parkinson's Disease. Revista Cefac, 20(2), 135-144. https://doi.org/10.1590/1982-0216201820213117
  • Shetty, K., Krishnan, S., Thulaseedharan, J. V., Mohan, M., & Kishore, A. (2019). Asymptomatic Hearing Impairment Frequently Occurs in Early-Onset Parkinson's Disease. J Mov Disord, 12(2), 84-90. https://doi.org/10.14802/jmd.18048 Uluyol, S., Kilicaslan, S., Baydar, C., & ŞENER, U. (2016). Hearing impairment and tinnitus severity in Parkinson’s disease. Turkish Journal of Geriatrics/Türk Geriatri Dergisi, 19(4). Vitale, C., Marcelli, V., Abate, T., Pianese, A., Allocca, R., Moccia, M., . . . Cavaliere, M. (2016). Speech discrimination is impaired in parkinsonian patients: Expanding the audiologic findings of Parkinson's disease. Parkinsonism Relat Disord, 22 Suppl 1, S138-143. https://doi.org/10.1016/j.parkreldis.2015.09.040 Vitale, C., Marcelli, V., Allocca, R., Santangelo, G., Riccardi, P., Erro, R., . . . Barone, P. (2012). Hearing Impairment in Parkinson's Disease: Expanding the Nonmotor Phenotype. Movement Disorders, 27(12), 1530-1535. https://doi.org/10.1002/mds.25149
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri (Diğer)
Bölüm Araştırma Makaleleri
Yazarlar

Büşra Kaynakoğlu 0000-0003-0528-1086

Mustafa Gokcan 0000-0002-4160-7349

Yayımlanma Tarihi 28 Şubat 2025
Gönderilme Tarihi 12 Aralık 2024
Kabul Tarihi 13 Ocak 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 6 Sayı: 1

Kaynak Göster

APA Kaynakoğlu, B., & Gokcan, M. (2025). PARKİNSON HASTALIĞINDA ODYOLOJİK BULGULAR. Selçuk Sağlık Dergisi, 6(1), 190-200. https://doi.org/10.70813/ssd.1598913