Yıl 2019, Cilt 1 , Sayı 1, Sayfalar 34 - 41 2019-08-30

In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?

Murat ŞAHİN [1] , Kemal PEKER [2] , Ali Seydi BOZKURT [3]


Objectives: Postdural puncture headache (PDPH) is a complication that may arise following spinal anesthesia. We investigated whether homocysteine and C-reactive protein levels may be associated in the development of PDPH in patients that received spinal anesthesia.

Materials and Methods: In order to determine homocysteine and C-reactive protein (CRP) levels, blood samples were taken from patients before and one day following spinal anesthesia. A total of 100 male patients were enrolled in the study. The mean age of the patients was 29 years old. Out of all the patients, a total of 6 developed headaches. The Mann-Whitney U-test was used to compare homocysteine and CRP levels between patients that did and did not develop headaches.

Results: Homocysteine levels before and after the operation were higher in subjects that developed a headache as compared to patients that did not develop headaches (p<0.001). CRP levels did not differ significantly between patients with headaches and patients that did not experience them (p>0.05).

Conclusions: High blood levels of homocysteine in patients with PDPH might be used as a biomarker so to predict the development of PDPH. However, future larger, multi-center studies are needed to further elucidate this association.

Spinal Anesthesia, Postdural Puncture Headache, Homocysteine, C-Reactive Proteine
  • Referans 1.Bedirli N, Akkaya T: Postspinal Başağrısı. Anestezi Dergisi. 2010:18(3):135-140
Birincil Dil en
Konular Temel Sağlık Hizmetleri
Bölüm Research Articles
Yazarlar

Yazar: Murat ŞAHİN
Kurum: AMASYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, ANESTEZİYOLOJİ VE REANİMASYON ANABİLİM DALI
Ülke: Turkey


Yazar: Kemal PEKER
Kurum: SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, GENEL CERRAHİ ANABİLİM DALI
Ülke: Turkey


Yazar: Ali Seydi BOZKURT
Kurum: ERZİNCAN BİNALİ YILDIRIM ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, ÜROLOJİ ANABİLİM DALI
Ülke: Turkey


Destekleyen Kurum Erzincan Binali Yıldırım Üniversitesi Bilimsel Araştırma Projesi
Proje Numarası 2012/12.01.08
Tarihler

Yayımlanma Tarihi : 30 Ağustos 2019

Bibtex @araştırma makalesi { sshs599681, journal = {Sabuncuoglu Serefeddin Health Sciences}, issn = {2667-6338}, address = {Amasya Üniversitesş Sabuncuoğlu Şerefeddin Sağlık Hizmetleri Meslek Yüksek Okulu İpekköy/Amasya}, publisher = {Amasya Üniversitesi}, year = {2019}, volume = {1}, pages = {34 - 41}, doi = {}, title = {In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?}, key = {cite}, author = {ŞAHİN, Murat and PEKER, Kemal and BOZKURT, Ali Seydi} }
APA ŞAHİN, M , PEKER, K , BOZKURT, A . (2019). In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?. Sabuncuoglu Serefeddin Health Sciences , 1 (1) , 34-41 . Retrieved from https://dergipark.org.tr/tr/pub/sshs/issue/48459/599681
MLA ŞAHİN, M , PEKER, K , BOZKURT, A . "In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?". Sabuncuoglu Serefeddin Health Sciences 1 (2019 ): 34-41 <https://dergipark.org.tr/tr/pub/sshs/issue/48459/599681>
Chicago ŞAHİN, M , PEKER, K , BOZKURT, A . "In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?". Sabuncuoglu Serefeddin Health Sciences 1 (2019 ): 34-41
RIS TY - JOUR T1 - In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache? AU - Murat ŞAHİN , Kemal PEKER , Ali Seydi BOZKURT Y1 - 2019 PY - 2019 N1 - DO - T2 - Sabuncuoglu Serefeddin Health Sciences JF - Journal JO - JOR SP - 34 EP - 41 VL - 1 IS - 1 SN - 2667-6338- M3 - UR - Y2 - 2019 ER -
EndNote %0 Sabuncuoglu Serefeddin Health Sciences In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache? %A Murat ŞAHİN , Kemal PEKER , Ali Seydi BOZKURT %T In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache? %D 2019 %J Sabuncuoglu Serefeddin Health Sciences %P 2667-6338- %V 1 %N 1 %R %U
ISNAD ŞAHİN, Murat , PEKER, Kemal , BOZKURT, Ali Seydi . "In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?". Sabuncuoglu Serefeddin Health Sciences 1 / 1 (Ağustos 2019): 34-41 .
AMA ŞAHİN M , PEKER K , BOZKURT A . In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?. SSHS. 2019; 1(1): 34-41.
Vancouver ŞAHİN M , PEKER K , BOZKURT A . In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?. Sabuncuoglu Serefeddin Health Sciences. 2019; 1(1): 41-34.