Araştırma Makalesi
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Yıl 2025, Cilt: 10 Sayı: 4, 920 - 935, 30.12.2025
https://doi.org/10.30622/tarr.1800377

Öz

Kaynakça

  • Aaltonen, K. (2023). Austerity, economic hardship and access to medications: a repeated cross-sectional population survey study, 2013–2020. J Epidemiol Community Health, 77(3), 160-167. https://doi.org/10.1136/jech-2022-219706
  • Alexander, G. C., & Qato, D. M. (2020). Ensuring access to medications in the US during the COVID-19 pandemic. JAMA, 324(1), 31–32. https://doi.org/10.1001/jama.2020.6016
  • Al-Hanawi, M. K., & Keetile, M. (2024). Determinants of out-of-pocket expenditure on medicines among adults in Saudi Arabia: a cross-sectional study. Frontiers in medicine, 11, 1478412. https://doi.org/10.3389/fmed.2024.1478412
  • Baltagi, B. H. (2008). Econometric analysis of panel data (Vol. 4, pp. 135-145). Chichester: John Wiley & Sons. https://doi.org/10.1007/978-3-030-53953-5
  • Belloni, A., Morgan, D., & Paris, V. (2016). Pharmaceutical expenditure and policies: Past trends and future challenges. OECD Publishing.
  • Bölükbaşı, N., Işık, H., & Söyler, S. (2020). Relationships between pharmaceutical expenditures and life expectancy: Assessment for Turkey and OECD countries. Sağlık Akademisyenleri Dergisi, 7(3), 183–187.
  • Bölükbaşı, N., Işık, H., ve Söyler, S. (2021). Sağlık harcamaları ve ilaç harcamaları ilişkisi: Türkiye ve OECD ülkeleri açısından bir karşılaştırma. Uluslararası Sağlık Yönetimi ve Stratejileri Araştırma Dergisi, 7(1), 47–56.
  • Clemente, J., Marcuello, C., & Montanes, A. (2007). Editorial identification of treatment effects. Health Economics, 17, 1187–1206.
  • Costa-Font, J., Kanavos, P., & Rovira, J. (2007). Determinants of out-of-pocket pharmaceutical expenditure and access to drugs in Catalonia. Applied Economics, 39(5), 541–551. https://doi.org/10.1080/00036840500438947
  • Cylus, J., Glymour, M. M., & Avendano, M. (2015). Health effects of unemployment benefit program generosity. American Journal of Public Health, 105(2), 317–323. https://doi.org/10.2105/AJPH.2014.302253
  • Driscoll, J. C., & Kraay, A. C. (1998). Consistent covariance matrix estimation with spatially dependent panel data. Review of Economics and Statistics, 80(4), 549–560. https://doi.org/10.1162/003465398557825
  • Du, J., Yang, X., Chen, M., & Wang, Z. (2019). Socioeconomic determinants of out-of-pocket pharmaceutical expenditure among middle-aged and elderly adults based on the China Health and Retirement Longitudinal Survey. BMJ Open, 9(7), e024936. https://doi.org/10.1136/bmjopen-2018-024936
  • Godman, B., Malmström, R. E., Diogene, E., Gray, A., Jayathissa, S., Timoney, A., ... & Gustafsson, L. L. (2015). Are new models needed to optimize the utilization of new medicines to sustain healthcare systems? Expert Review of Clinical Pharmacology, 8(1), 77–94. https://doi.org/10.1586/17512433.2015.990380
  • Imani, A., Rasekh, H. R., & Golestani, M. (2014). The relationship between pharmaceutical expenditures, health care expenditures and gross domestic product in Iran: 1999–2008. Pharmaceutical Sciences, 18(1), 9–17.
  • Joshi, J. M., Dalei, N. N., & Mehta, P. (2021). Estimation of gross refining margin of Indian petroleum refineries using Driscoll-Kraay standard error estimator. Energy Policy, 150, 112148. https://doi.org/10.1016/j.enpol.2021.112148
  • Kadkhodamanesh, A., Varahrami, V., Zarei, L., Peiravian, F., Hadidi, M., & Yousefi, N. (2021). Investigation of the determinants of pharmaceutical expenditure share of GDP in Iran and selected OECD countries. Journal of Pharmaceutical Policy and Practice, 14(1), 82. https://doi.org/10.1186/s40545-021-00371-2
  • Leivaditis, V., Ntais, C., Fanourgiakis, J., Mulita, F., & Kontodimopoulos, N. (2025). International experience in the management of pharmaceutical expenditure: A narrative literature review. British Journal of Hospital Medicine, 86(3), 1–19. https://doi.org/10.12968/hmed.2024.0676
  • Machado, M., O'Brodovich, R., Krahn, M., & Einarson, T. R. (2011). International drug price comparisons: Quality assessment. Revista Panamericana de Salud Pública, 29(1), 46–51.
  • Maniadakis, N., Kourlaba, G., Zavali, M., Zampoulakis, D., & Mylonas, C. (2016). Factors affecting pharmaceutical expenditures: A systematic review. Value in Health, 19(7), A457.
  • Morgan, S. G. (2005). Booming prescription drug expenditure: A population-based analysis of age dynamics. Medical Care, 43(10), 996–1008. https://doi.org/10.1097/01.mlr.0000178217.84354.f1
  • Morgan, S., & Cunningham, C. (2011). Population aging and the determinants of healthcare expenditures: The case of hospital, medical and pharmaceutical care in British Columbia, 1996 to 2006. Healthcare Policy, 7(1), 68–81.
  • Mousnad, M. A., Shafie, A. A., & Ibrahim, M. I. (2014). Systematic review of factors affecting pharmaceutical expenditures. Health Policy, 116(2–3), 137–146. https://doi.org/10.1016/j.healthpol.2014.03.010
  • Nguyen, A., Guttentag, A., Li, D., & Meijgaard, J. V. (2022). The impact of job and insurance loss on prescription drug use: a panel data approach to quantifying the health consequences of unemployment during the COVID-19 pandemic. International Journal of Health Services, 52(3), 312-322. https://doi.org/10.1177/00207314221078749
  • OECD. (2025a). OECD data: Indicators. OECD. Retrieved April 28, 2025, from, https://www.oecd.org/en/data/indicators.html?orderBy=mostRelevant&page=0&facetTags=oecd-languages%3Aen
  • OECD. (2025b). Pharmaceutical spending (indicator). OECD Data. Retrieved April 28, 2025, from https://www.oecd.org/en/data/indicators/pharmaceutical-spending.html
  • Sanwald, A., & Theurl, E. (2017). Out-of-pocket expenditures for pharmaceuticals: Lessons from the Austrian household budget survey. The European Journal of Health Economics, 18, 435–447. https://doi.org/10.1007/s10198-016-0797-y
  • Shaikh, M., & Gandjour, A. (2019). Pharmaceutical expenditure and gross domestic product: Evidence of simultaneous effects using a two-step instrumental variables strategy. Health Economics, 28(1), 101–122. https://doi.org/10.1002/hec.3832
  • Son, B. W. (2017). Pharmaceutical spending and policy implications. Journal of Applied Business and Economics, 19(9), 125–135.
  • Şahin, B. E. (2012). Kamu Harcamaları İçinde İlaç Harcamalarının Yeri ve Ekonomik Büyüme İlişkisi [Yayınlanmamış Doktora Tezi] İstanbul Üniversitesi Sosyal Bilimeler Enstitüsü
  • Şenol, O., Akbulut, F., Gençtürk, M., ve Gökkaya, D. (2022). Ekonomik değişkenlerin ilaç harcamaları üzerine etkisinin panel veri analiz yöntemi ile incelenmesi. Journal of Management and Economics Research, 20(2), 54–75. https://doi.org/10.11611/yead.979567
  • Thomas, R. K., & Thomas, R. K. (2021). Health services demand and utilization. In Health Services Planning (pp. 91–114). Springer.
  • Tichy, E. M., Hoffman, J. M., Suda, K. J., Rim, M. H., Tadrous, M., Cuellar, S., ... & Schumock, G. T. (2022). National trends in prescription drug expenditures and projections for 2022. American Journal of Health-System Pharmacy, 79(14), 1158–1172. https://doi.org/10.1093/ajhp/zxab160
  • Tichy, E. M., Hoffman, J. M., Tadrous, M., Rim, M. H., Suda, K. J., Cuellar, S., ... & Schumock, G. T. (2023). National trends in prescription drug expenditures and projections for 2023. American Journal of Health-System Pharmacy, 80(14), 899–913. https://doi.org/10.1093/ajhp/zxad086
  • Top, M., ve Tarcan, M. (2004). Türkiye ilaç ekonomisi ve ilaç harcamaları 1998–2003 dönemi değerlendirmesi. Liberal Düşünce, 9, 95–110.
  • Vandegrift, D., & Datta, A. (2006). Prescription drug expenditures in the United States: The effects of obesity, demographics, and new pharmaceutical products. Southern Economic Journal, 73(2), 515–529. https://doi.org/10.1002/j.2325-8012.2006.tb00784.x
  • Wooldridge, J. M. (2010). Econometric analysis of cross section and panel data. MIT press.
  • Xiong, Y., Cui, Y., & Zhang, X. (2022). Pharmaceutical expenditure and total health-care expenditure in OECD countries and China: Bidirectional Granger causality on the basis of health level. Expert Review of Pharmacoeconomics & Outcomes Research, 22(3), 505–512. https://doi.org/10.1080/14737167.2019.1605292
  • Zeitouny, S., McGrail, K., Tadrous, M., Wong, S. T., Cheng, L., & Law, M. (2024). Impact of the COVID-19 pandemic on prescription drug use and costs in British Columbia: A retrospective interrupted time series study. BMJ Open, 14(1), e070031. https://doi.org/10.1136/bmjopen-2022-070031

OECD Ülkelerinde İlaç Harcamalarının Belirleyicileri

Yıl 2025, Cilt: 10 Sayı: 4, 920 - 935, 30.12.2025
https://doi.org/10.30622/tarr.1800377

Öz

İlaç harcamaları, 1970’ten bu yana GSYİH’nin payı olarak istikrarlı bir şekilde artmaktadır. Bununla birlikte, toplam sağlık harcamaları da artmıştır. Sonuç olarak, ilaç harcamaları OECD ülkelerinde toplam sağlık harcamaları içindeki ortalama payını korumuş ve %15’e yakın bir orana ulaşmıştır. Ülkeler genelinde, kişi başına ilaç harcamaları göreceli gelirlere bağlı olmakla birlikte kurumsal özelliklerden de etkilenmektedir. Bu nedenle, ilaç harcamalarındaki eğilimler, genel sağlık harcama modellerinin belirlenmesinde büyük rol oynamaktadır. İlaç harcamalarındaki eğilimler; mevcut ilaçların fiyatlarındaki değişiklikler, tüketilen hacimdeki dalgalanmalar ve kullanılan ilaçların terapötik bileşimindeki farklılaşmaların birleşiminden kaynaklanabilir. Bu bileşenler ise demografik ve epidemiyolojik eğilimler, ilaç pazarlarının dinamikleri ile tıp uygulamaları ve ilaç politikalarındaki değişiklikler gibi çeşitli faktörlerden etkilenebilir. Bu çalışma, ilaç harcamalarını etkileyen faktörleri belirlemek amacıyla tasarlanmıştır. Çalışmada, OECD veri tabanına kayıtlı 26 ülkeye ait veriler analize dâhil edilmiştir. Araştırma kapsamında, 2015-2022 yıllarını kapsayan dönem incelenmiştir. Çalışmanın amacı doğrultusunda, bağımlı değişken olarak kişi başına yapılan toplam ilaç harcamaları kullanılmıştır. Bağımsız değişkenler ise sağlık harcamalarının GSYİH içindeki payı, bireylerin sağlık algısı, kişi başına gelir, işsizlik oranı, alkol tüketimi, 65 yaş üstü nüfus oranı ve Covid-19 pandemisi olarak belirlenmiştir. Araştırmada panel veri analizi yöntemi uygulanmıştır. Analizler sonucunda, sağlık harcamalarının GSYİH içindeki payının, kişi başına gelirin ve Covid-19 pandemisinin kişi başına yapılan ilaç harcamaları üzerinde pozitif etkisi olduğu bulunmuştur. Ayrıca, işsizlik oranının ve 65 yaş üstü nüfus oranının ilaç harcamaları üzerinde negatif etkisi olduğu tespit edilmiştir. Son olarak, sağlık algısı ve alkol tüketiminin kişi başına yapılan ilaç harcamaları üzerinde anlamlı bir etkisinin bulunmadığı belirlenmiştir. Bu doğrultuda, politika yapıcıların sağlık bütçelerini planlarken yalnızca demografik eğilimlere değil, aynı zamanda ekonomik büyüme dinamiklerine ve istihdam politikalarına da odaklanmaları gerekmektedir.

Kaynakça

  • Aaltonen, K. (2023). Austerity, economic hardship and access to medications: a repeated cross-sectional population survey study, 2013–2020. J Epidemiol Community Health, 77(3), 160-167. https://doi.org/10.1136/jech-2022-219706
  • Alexander, G. C., & Qato, D. M. (2020). Ensuring access to medications in the US during the COVID-19 pandemic. JAMA, 324(1), 31–32. https://doi.org/10.1001/jama.2020.6016
  • Al-Hanawi, M. K., & Keetile, M. (2024). Determinants of out-of-pocket expenditure on medicines among adults in Saudi Arabia: a cross-sectional study. Frontiers in medicine, 11, 1478412. https://doi.org/10.3389/fmed.2024.1478412
  • Baltagi, B. H. (2008). Econometric analysis of panel data (Vol. 4, pp. 135-145). Chichester: John Wiley & Sons. https://doi.org/10.1007/978-3-030-53953-5
  • Belloni, A., Morgan, D., & Paris, V. (2016). Pharmaceutical expenditure and policies: Past trends and future challenges. OECD Publishing.
  • Bölükbaşı, N., Işık, H., & Söyler, S. (2020). Relationships between pharmaceutical expenditures and life expectancy: Assessment for Turkey and OECD countries. Sağlık Akademisyenleri Dergisi, 7(3), 183–187.
  • Bölükbaşı, N., Işık, H., ve Söyler, S. (2021). Sağlık harcamaları ve ilaç harcamaları ilişkisi: Türkiye ve OECD ülkeleri açısından bir karşılaştırma. Uluslararası Sağlık Yönetimi ve Stratejileri Araştırma Dergisi, 7(1), 47–56.
  • Clemente, J., Marcuello, C., & Montanes, A. (2007). Editorial identification of treatment effects. Health Economics, 17, 1187–1206.
  • Costa-Font, J., Kanavos, P., & Rovira, J. (2007). Determinants of out-of-pocket pharmaceutical expenditure and access to drugs in Catalonia. Applied Economics, 39(5), 541–551. https://doi.org/10.1080/00036840500438947
  • Cylus, J., Glymour, M. M., & Avendano, M. (2015). Health effects of unemployment benefit program generosity. American Journal of Public Health, 105(2), 317–323. https://doi.org/10.2105/AJPH.2014.302253
  • Driscoll, J. C., & Kraay, A. C. (1998). Consistent covariance matrix estimation with spatially dependent panel data. Review of Economics and Statistics, 80(4), 549–560. https://doi.org/10.1162/003465398557825
  • Du, J., Yang, X., Chen, M., & Wang, Z. (2019). Socioeconomic determinants of out-of-pocket pharmaceutical expenditure among middle-aged and elderly adults based on the China Health and Retirement Longitudinal Survey. BMJ Open, 9(7), e024936. https://doi.org/10.1136/bmjopen-2018-024936
  • Godman, B., Malmström, R. E., Diogene, E., Gray, A., Jayathissa, S., Timoney, A., ... & Gustafsson, L. L. (2015). Are new models needed to optimize the utilization of new medicines to sustain healthcare systems? Expert Review of Clinical Pharmacology, 8(1), 77–94. https://doi.org/10.1586/17512433.2015.990380
  • Imani, A., Rasekh, H. R., & Golestani, M. (2014). The relationship between pharmaceutical expenditures, health care expenditures and gross domestic product in Iran: 1999–2008. Pharmaceutical Sciences, 18(1), 9–17.
  • Joshi, J. M., Dalei, N. N., & Mehta, P. (2021). Estimation of gross refining margin of Indian petroleum refineries using Driscoll-Kraay standard error estimator. Energy Policy, 150, 112148. https://doi.org/10.1016/j.enpol.2021.112148
  • Kadkhodamanesh, A., Varahrami, V., Zarei, L., Peiravian, F., Hadidi, M., & Yousefi, N. (2021). Investigation of the determinants of pharmaceutical expenditure share of GDP in Iran and selected OECD countries. Journal of Pharmaceutical Policy and Practice, 14(1), 82. https://doi.org/10.1186/s40545-021-00371-2
  • Leivaditis, V., Ntais, C., Fanourgiakis, J., Mulita, F., & Kontodimopoulos, N. (2025). International experience in the management of pharmaceutical expenditure: A narrative literature review. British Journal of Hospital Medicine, 86(3), 1–19. https://doi.org/10.12968/hmed.2024.0676
  • Machado, M., O'Brodovich, R., Krahn, M., & Einarson, T. R. (2011). International drug price comparisons: Quality assessment. Revista Panamericana de Salud Pública, 29(1), 46–51.
  • Maniadakis, N., Kourlaba, G., Zavali, M., Zampoulakis, D., & Mylonas, C. (2016). Factors affecting pharmaceutical expenditures: A systematic review. Value in Health, 19(7), A457.
  • Morgan, S. G. (2005). Booming prescription drug expenditure: A population-based analysis of age dynamics. Medical Care, 43(10), 996–1008. https://doi.org/10.1097/01.mlr.0000178217.84354.f1
  • Morgan, S., & Cunningham, C. (2011). Population aging and the determinants of healthcare expenditures: The case of hospital, medical and pharmaceutical care in British Columbia, 1996 to 2006. Healthcare Policy, 7(1), 68–81.
  • Mousnad, M. A., Shafie, A. A., & Ibrahim, M. I. (2014). Systematic review of factors affecting pharmaceutical expenditures. Health Policy, 116(2–3), 137–146. https://doi.org/10.1016/j.healthpol.2014.03.010
  • Nguyen, A., Guttentag, A., Li, D., & Meijgaard, J. V. (2022). The impact of job and insurance loss on prescription drug use: a panel data approach to quantifying the health consequences of unemployment during the COVID-19 pandemic. International Journal of Health Services, 52(3), 312-322. https://doi.org/10.1177/00207314221078749
  • OECD. (2025a). OECD data: Indicators. OECD. Retrieved April 28, 2025, from, https://www.oecd.org/en/data/indicators.html?orderBy=mostRelevant&page=0&facetTags=oecd-languages%3Aen
  • OECD. (2025b). Pharmaceutical spending (indicator). OECD Data. Retrieved April 28, 2025, from https://www.oecd.org/en/data/indicators/pharmaceutical-spending.html
  • Sanwald, A., & Theurl, E. (2017). Out-of-pocket expenditures for pharmaceuticals: Lessons from the Austrian household budget survey. The European Journal of Health Economics, 18, 435–447. https://doi.org/10.1007/s10198-016-0797-y
  • Shaikh, M., & Gandjour, A. (2019). Pharmaceutical expenditure and gross domestic product: Evidence of simultaneous effects using a two-step instrumental variables strategy. Health Economics, 28(1), 101–122. https://doi.org/10.1002/hec.3832
  • Son, B. W. (2017). Pharmaceutical spending and policy implications. Journal of Applied Business and Economics, 19(9), 125–135.
  • Şahin, B. E. (2012). Kamu Harcamaları İçinde İlaç Harcamalarının Yeri ve Ekonomik Büyüme İlişkisi [Yayınlanmamış Doktora Tezi] İstanbul Üniversitesi Sosyal Bilimeler Enstitüsü
  • Şenol, O., Akbulut, F., Gençtürk, M., ve Gökkaya, D. (2022). Ekonomik değişkenlerin ilaç harcamaları üzerine etkisinin panel veri analiz yöntemi ile incelenmesi. Journal of Management and Economics Research, 20(2), 54–75. https://doi.org/10.11611/yead.979567
  • Thomas, R. K., & Thomas, R. K. (2021). Health services demand and utilization. In Health Services Planning (pp. 91–114). Springer.
  • Tichy, E. M., Hoffman, J. M., Suda, K. J., Rim, M. H., Tadrous, M., Cuellar, S., ... & Schumock, G. T. (2022). National trends in prescription drug expenditures and projections for 2022. American Journal of Health-System Pharmacy, 79(14), 1158–1172. https://doi.org/10.1093/ajhp/zxab160
  • Tichy, E. M., Hoffman, J. M., Tadrous, M., Rim, M. H., Suda, K. J., Cuellar, S., ... & Schumock, G. T. (2023). National trends in prescription drug expenditures and projections for 2023. American Journal of Health-System Pharmacy, 80(14), 899–913. https://doi.org/10.1093/ajhp/zxad086
  • Top, M., ve Tarcan, M. (2004). Türkiye ilaç ekonomisi ve ilaç harcamaları 1998–2003 dönemi değerlendirmesi. Liberal Düşünce, 9, 95–110.
  • Vandegrift, D., & Datta, A. (2006). Prescription drug expenditures in the United States: The effects of obesity, demographics, and new pharmaceutical products. Southern Economic Journal, 73(2), 515–529. https://doi.org/10.1002/j.2325-8012.2006.tb00784.x
  • Wooldridge, J. M. (2010). Econometric analysis of cross section and panel data. MIT press.
  • Xiong, Y., Cui, Y., & Zhang, X. (2022). Pharmaceutical expenditure and total health-care expenditure in OECD countries and China: Bidirectional Granger causality on the basis of health level. Expert Review of Pharmacoeconomics & Outcomes Research, 22(3), 505–512. https://doi.org/10.1080/14737167.2019.1605292
  • Zeitouny, S., McGrail, K., Tadrous, M., Wong, S. T., Cheng, L., & Law, M. (2024). Impact of the COVID-19 pandemic on prescription drug use and costs in British Columbia: A retrospective interrupted time series study. BMJ Open, 14(1), e070031. https://doi.org/10.1136/bmjopen-2022-070031

Determinants of Pharmaceutical Expenditures in OECD Countries

Yıl 2025, Cilt: 10 Sayı: 4, 920 - 935, 30.12.2025
https://doi.org/10.30622/tarr.1800377

Öz

Pharmaceutical expenditure has been increasing steadily as a share of GDP since 1970. However, total health expenditure has also increased. As a result, pharmaceutical expenditure has maintained its average share of total health expenditure in OECD countries, reaching close to 15 percent. Across countries, per capita pharmaceutical expenditures depend on relative incomes but are also influenced by institutional characteristics. Therefore, trends in pharmaceutical expenditures play a major role in determining overall health expenditure patterns. Trends in pharmaceutical expenditure can result from a combination of changes in the prices of available medicines, fluctuations in the volume used, and variations in the therapeutic composition of the medicines used. These components can be influenced by a variety of factors, including demographic and epidemiological trends, the dynamics of pharmaceutical sectors, and changes in medical practice and drug policies. This study is designed to determine the factors affecting pharmaceutical expenditures. In the study, data from 26 countries registered in the OECD database were included in the analysis. Within the scope of the study, the period covering the years 2015-2022 was examined. For the purpose of the study, total per capita pharmaceutical expenditures were used as the dependent variable. The independent variables were determined as the share of health expenditures in GDP, individuals' perception of health, per capita income, unemployment rate, alcohol consumption, population over 65, and the Covid-19 pandemic. The panel data analysis method was applied in the study. As a result of the analyses, it was found that the share of health expenditures in GDP, per capita incomes and the Covid-19 pandemic have a positive effect on per capita drug expenditures. In addition, the unemployment rate and the proportion of the population over the age of 65 have a negative effect on drug expenditures. Finally, health perception and alcohol consumption were found to have no significant effect on per capita drug expenditures. Accordingly, policy makers should focus not only on demographic trends but also on economic growth dynamics and employment policies when planning health budgets.

Kaynakça

  • Aaltonen, K. (2023). Austerity, economic hardship and access to medications: a repeated cross-sectional population survey study, 2013–2020. J Epidemiol Community Health, 77(3), 160-167. https://doi.org/10.1136/jech-2022-219706
  • Alexander, G. C., & Qato, D. M. (2020). Ensuring access to medications in the US during the COVID-19 pandemic. JAMA, 324(1), 31–32. https://doi.org/10.1001/jama.2020.6016
  • Al-Hanawi, M. K., & Keetile, M. (2024). Determinants of out-of-pocket expenditure on medicines among adults in Saudi Arabia: a cross-sectional study. Frontiers in medicine, 11, 1478412. https://doi.org/10.3389/fmed.2024.1478412
  • Baltagi, B. H. (2008). Econometric analysis of panel data (Vol. 4, pp. 135-145). Chichester: John Wiley & Sons. https://doi.org/10.1007/978-3-030-53953-5
  • Belloni, A., Morgan, D., & Paris, V. (2016). Pharmaceutical expenditure and policies: Past trends and future challenges. OECD Publishing.
  • Bölükbaşı, N., Işık, H., & Söyler, S. (2020). Relationships between pharmaceutical expenditures and life expectancy: Assessment for Turkey and OECD countries. Sağlık Akademisyenleri Dergisi, 7(3), 183–187.
  • Bölükbaşı, N., Işık, H., ve Söyler, S. (2021). Sağlık harcamaları ve ilaç harcamaları ilişkisi: Türkiye ve OECD ülkeleri açısından bir karşılaştırma. Uluslararası Sağlık Yönetimi ve Stratejileri Araştırma Dergisi, 7(1), 47–56.
  • Clemente, J., Marcuello, C., & Montanes, A. (2007). Editorial identification of treatment effects. Health Economics, 17, 1187–1206.
  • Costa-Font, J., Kanavos, P., & Rovira, J. (2007). Determinants of out-of-pocket pharmaceutical expenditure and access to drugs in Catalonia. Applied Economics, 39(5), 541–551. https://doi.org/10.1080/00036840500438947
  • Cylus, J., Glymour, M. M., & Avendano, M. (2015). Health effects of unemployment benefit program generosity. American Journal of Public Health, 105(2), 317–323. https://doi.org/10.2105/AJPH.2014.302253
  • Driscoll, J. C., & Kraay, A. C. (1998). Consistent covariance matrix estimation with spatially dependent panel data. Review of Economics and Statistics, 80(4), 549–560. https://doi.org/10.1162/003465398557825
  • Du, J., Yang, X., Chen, M., & Wang, Z. (2019). Socioeconomic determinants of out-of-pocket pharmaceutical expenditure among middle-aged and elderly adults based on the China Health and Retirement Longitudinal Survey. BMJ Open, 9(7), e024936. https://doi.org/10.1136/bmjopen-2018-024936
  • Godman, B., Malmström, R. E., Diogene, E., Gray, A., Jayathissa, S., Timoney, A., ... & Gustafsson, L. L. (2015). Are new models needed to optimize the utilization of new medicines to sustain healthcare systems? Expert Review of Clinical Pharmacology, 8(1), 77–94. https://doi.org/10.1586/17512433.2015.990380
  • Imani, A., Rasekh, H. R., & Golestani, M. (2014). The relationship between pharmaceutical expenditures, health care expenditures and gross domestic product in Iran: 1999–2008. Pharmaceutical Sciences, 18(1), 9–17.
  • Joshi, J. M., Dalei, N. N., & Mehta, P. (2021). Estimation of gross refining margin of Indian petroleum refineries using Driscoll-Kraay standard error estimator. Energy Policy, 150, 112148. https://doi.org/10.1016/j.enpol.2021.112148
  • Kadkhodamanesh, A., Varahrami, V., Zarei, L., Peiravian, F., Hadidi, M., & Yousefi, N. (2021). Investigation of the determinants of pharmaceutical expenditure share of GDP in Iran and selected OECD countries. Journal of Pharmaceutical Policy and Practice, 14(1), 82. https://doi.org/10.1186/s40545-021-00371-2
  • Leivaditis, V., Ntais, C., Fanourgiakis, J., Mulita, F., & Kontodimopoulos, N. (2025). International experience in the management of pharmaceutical expenditure: A narrative literature review. British Journal of Hospital Medicine, 86(3), 1–19. https://doi.org/10.12968/hmed.2024.0676
  • Machado, M., O'Brodovich, R., Krahn, M., & Einarson, T. R. (2011). International drug price comparisons: Quality assessment. Revista Panamericana de Salud Pública, 29(1), 46–51.
  • Maniadakis, N., Kourlaba, G., Zavali, M., Zampoulakis, D., & Mylonas, C. (2016). Factors affecting pharmaceutical expenditures: A systematic review. Value in Health, 19(7), A457.
  • Morgan, S. G. (2005). Booming prescription drug expenditure: A population-based analysis of age dynamics. Medical Care, 43(10), 996–1008. https://doi.org/10.1097/01.mlr.0000178217.84354.f1
  • Morgan, S., & Cunningham, C. (2011). Population aging and the determinants of healthcare expenditures: The case of hospital, medical and pharmaceutical care in British Columbia, 1996 to 2006. Healthcare Policy, 7(1), 68–81.
  • Mousnad, M. A., Shafie, A. A., & Ibrahim, M. I. (2014). Systematic review of factors affecting pharmaceutical expenditures. Health Policy, 116(2–3), 137–146. https://doi.org/10.1016/j.healthpol.2014.03.010
  • Nguyen, A., Guttentag, A., Li, D., & Meijgaard, J. V. (2022). The impact of job and insurance loss on prescription drug use: a panel data approach to quantifying the health consequences of unemployment during the COVID-19 pandemic. International Journal of Health Services, 52(3), 312-322. https://doi.org/10.1177/00207314221078749
  • OECD. (2025a). OECD data: Indicators. OECD. Retrieved April 28, 2025, from, https://www.oecd.org/en/data/indicators.html?orderBy=mostRelevant&page=0&facetTags=oecd-languages%3Aen
  • OECD. (2025b). Pharmaceutical spending (indicator). OECD Data. Retrieved April 28, 2025, from https://www.oecd.org/en/data/indicators/pharmaceutical-spending.html
  • Sanwald, A., & Theurl, E. (2017). Out-of-pocket expenditures for pharmaceuticals: Lessons from the Austrian household budget survey. The European Journal of Health Economics, 18, 435–447. https://doi.org/10.1007/s10198-016-0797-y
  • Shaikh, M., & Gandjour, A. (2019). Pharmaceutical expenditure and gross domestic product: Evidence of simultaneous effects using a two-step instrumental variables strategy. Health Economics, 28(1), 101–122. https://doi.org/10.1002/hec.3832
  • Son, B. W. (2017). Pharmaceutical spending and policy implications. Journal of Applied Business and Economics, 19(9), 125–135.
  • Şahin, B. E. (2012). Kamu Harcamaları İçinde İlaç Harcamalarının Yeri ve Ekonomik Büyüme İlişkisi [Yayınlanmamış Doktora Tezi] İstanbul Üniversitesi Sosyal Bilimeler Enstitüsü
  • Şenol, O., Akbulut, F., Gençtürk, M., ve Gökkaya, D. (2022). Ekonomik değişkenlerin ilaç harcamaları üzerine etkisinin panel veri analiz yöntemi ile incelenmesi. Journal of Management and Economics Research, 20(2), 54–75. https://doi.org/10.11611/yead.979567
  • Thomas, R. K., & Thomas, R. K. (2021). Health services demand and utilization. In Health Services Planning (pp. 91–114). Springer.
  • Tichy, E. M., Hoffman, J. M., Suda, K. J., Rim, M. H., Tadrous, M., Cuellar, S., ... & Schumock, G. T. (2022). National trends in prescription drug expenditures and projections for 2022. American Journal of Health-System Pharmacy, 79(14), 1158–1172. https://doi.org/10.1093/ajhp/zxab160
  • Tichy, E. M., Hoffman, J. M., Tadrous, M., Rim, M. H., Suda, K. J., Cuellar, S., ... & Schumock, G. T. (2023). National trends in prescription drug expenditures and projections for 2023. American Journal of Health-System Pharmacy, 80(14), 899–913. https://doi.org/10.1093/ajhp/zxad086
  • Top, M., ve Tarcan, M. (2004). Türkiye ilaç ekonomisi ve ilaç harcamaları 1998–2003 dönemi değerlendirmesi. Liberal Düşünce, 9, 95–110.
  • Vandegrift, D., & Datta, A. (2006). Prescription drug expenditures in the United States: The effects of obesity, demographics, and new pharmaceutical products. Southern Economic Journal, 73(2), 515–529. https://doi.org/10.1002/j.2325-8012.2006.tb00784.x
  • Wooldridge, J. M. (2010). Econometric analysis of cross section and panel data. MIT press.
  • Xiong, Y., Cui, Y., & Zhang, X. (2022). Pharmaceutical expenditure and total health-care expenditure in OECD countries and China: Bidirectional Granger causality on the basis of health level. Expert Review of Pharmacoeconomics & Outcomes Research, 22(3), 505–512. https://doi.org/10.1080/14737167.2019.1605292
  • Zeitouny, S., McGrail, K., Tadrous, M., Wong, S. T., Cheng, L., & Law, M. (2024). Impact of the COVID-19 pandemic on prescription drug use and costs in British Columbia: A retrospective interrupted time series study. BMJ Open, 14(1), e070031. https://doi.org/10.1136/bmjopen-2022-070031
Toplam 38 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Politikası, Hastane İşletmeciliği
Bölüm Araştırma Makalesi
Yazarlar

İsmail Biçer 0000-0003-1878-0546

Gönderilme Tarihi 9 Ekim 2025
Kabul Tarihi 16 Aralık 2025
Yayımlanma Tarihi 30 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 10 Sayı: 4

Kaynak Göster

APA Biçer, İ. (2025). OECD Ülkelerinde İlaç Harcamalarının Belirleyicileri. Turkish Academic Research Review, 10(4), 920-935. https://doi.org/10.30622/tarr.1800377

Turkish Academic Research Review 
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