Zinc Spray for Treatment of Acrodermatitis Enteropathica: A Case Report

Yıl 2024, , 320 - 322, 24.09.2024

Emine Özdemir , Methiye Doğan , Esra Babayiğit , Nuriye Tarakçı , Hüseyin Altunhan

https://doi.org/10.12956/tchd.1479575

Öz

Acrodermatitis enteropathica is a rare disorder caused by zinc deficiency. The classic triad of symptoms includes perioral dermatitis, diarrhea, and alopecia. A rare cause of the acquired form is zinc deficiency due to total parenteral nutrition. Diagnosis can be challenging due to nonspecific symptoms. This paper presents a case of acrodermatitis enteropathica in a 5-month-old infant who had been on total parenteral nutrition since birth. Unlike the literature, the patient’s clinical improvement was observed with zinc spray and zinc cream treatment.

Anahtar Kelimeler

Acrodermatitis enteropathica, Zinc deficiency, Zinc spray

Akrodermatitis Enteropatika Tedavisinde Çinko Sprey: Olgu sunumu

Öz

Akrodermatitis enteropatika çinko eksikliğinin neden olduğu nadir görülen bir hastalıktır. Klasik triadı perioral dermatit, diyare ve alopesidir. Kazanılmış formunun nadir bir nedeni total parenteral beslenmeye bağlı eksik çinko alımıdır. Belirti ve bulguları spesifik olmadığı için tanı koymak zordur. Biz bu makalede doğduğundan beri total parenteral beslenen 5 aylık bir hastada gelişen akrodermatitis enteropatika olgusunun literatürden farklı olarak çinko sprey ve çinko krem tedavisi ile görülen klinik iyileşmesini sunuyoruz.

Anahtar Kelimeler

Akrodermatitis enteropatika, Çinko eksikliği, Çinko sprey

Kaynakça

• Glutsch V, Hamm H, Goebeler M. Zinc and skin: an update. J Dtsch Dermatol Ges 2019;17:589-96.
• Saper RB, Rash R. Zinc: an essential micronutrient. Am Fam Physician 2009;79:768-72.
• Baruch D, Naga L, Driscoll M, Kao G. Acrodermatitis enteropathica from zinc-deficient total parenteral nutrition. Cutis 2018;101:450-3.
• Wiznia LE, Bhansali S, Brinster N, Al-Qaqaa YM, Orlow SJ, Oza V. Acquired acrodermatitis enteropathica due to zinc-depleted parenteral nutrition. Pediatr Dermatol 2019;36:520-3.
• Maverakis E, Fung MA, Lynch PJ, Draznin M, Michael DJ, Ruben B, et al. Acrodermatitis enteropathica and an overview of zinc metabolism. J Am Acad Dermatol 2007;56:116-24.
• D’Amico G, De Laet C, Smits G, Salik D, Deprez G, Vilain C, et al. Acquired Zinc Deficiency Mimicking Acrodermatitis Enteropathica in a Breast-Fed Premature Infant. Pediatr Rep 2021;13:444-9.
• Alwadany MM, Al Wadani AF, Almarri FH, Alyami HS, Al-Subaie MA. Acrodermatitis Enteropathica: A Rare Case with Lifelong Implications. Cureus 2023;15:e37783.
• Cleminson K, Hull PR, Price E, Green PJ. Acute onset of blisters in an infant with acrodermatitis enteropathica: A case report. SAGE Open Med Case Rep 2021;9:2050313X20984119.
• Önder S, Erdem H, Dere G. An Acrodermatitis Enteropathica Case. Van Med J2019; 26: 261-4.
• Proli F, Margiotta G, Ferretti S, Drosi A, Valentini P, Buonsenso D, et al. Acrodermatitis enteropathica during parenteral nutrition: a pediatric case report. Acta Biomed 2023;94:e2023180.
• Ciampo IRLD, Sawamura R, Ciampo LAD, Fernandes MIM. Acrodermatitis Enteropathica: Clinical Manifestations and Pediatric Diagnosis. Rev Paul Pediatr 2018;36:238-41.
• Okhovat JP, O’Leary R, Hu M, Zussman J, Binder S, Worswick S. Acrodermatitis enteropathica in a patient with short bowel syndrome. Cutis 2017;100: E4-E6.