Bir Çocuk Olguda Orf Hastalığı

Öz

Orf hastalığı, Parapoxvirus ailesinden Orf virüsün etken olduğu zoonotik bir enfeksiyon hastalığıdır. Koyun ve keçilerde yaygın olarak görülmektedir. Koyun, kuzu ve keçilerin ağız etrafında ve yün bulunmayan kısımlarında papülloveziküler ve kabuklanmış lezyonlara yol açar ve lezyonun kabuğundan çevreye yayılır. Küçükbaş hayvancılıkla uğraşanlarda sıklıkla ellerde nodüller ile kendini gösterir. Kendini sınırlayan ve tedavisiz iyileşen bir hastalık olmakla birlikte; akla gelmediği zaman şarbon gibi ülkemizde endemik olan diğer zoonotik hastalıklarla karıştırılabilir. Bu nedenle orf hastalığının bilinmesi, gereksiz ileri tetkik ve tedavileri engelleyecektir. Orf hastalığı kişisel hijyen önlemleri ile önlenebilen bir hastalıktır. Bu yazıda, 13 yaşındaki bir çocukta, öykü ve fizik muayene ile tanısı konulan bir orf olgusu sunuldu.

Anahtar Kelimeler

• Çocuk, Ektima, Kontagiozum, Orf, Parapoxvirus

Orf Disease in a Child

Öz

Orf disease is a zoonotic infectious disease caused by the Orf virus which is a member of the Parapoxvirus family. It is commonly seen in sheep and goats. It leads to papulovesicular and crusted sores around the mouth and the parts without wool of sheep, lambs and goats. Orf disease often manifests with hand nodules in people engaged in sheep and goat husbandry. The disease is self-limited and heals without treatment. Orf disease skin lesions can be misdiagnosed as other endemic zoonotic infections such as anthrax in our country if the disorder is not considered. Knowledge of Orf disease will therefore prevent unnecessary further evaluation and treatments. Orf disease can be prevented by personal hygiene measures. In this report, a 13-year-old boy with Orf disease who was diagnosed with the history and physical examination is presented

Anahtar Kelimeler

• Child, Ecthyma, Contagiosum, Orf, Parapoxvirus

Kaynakça

1. Büttner M, Rziha HJ. Parapoxviruses: From the lesion to the viral genome. J Vet Med B Infect Dis Vet Public Health 2002;49:7-16.
2. Karakas A, Oguzoglu TC, Coskun O, Artuk C, Mert G, Gul HC, et al. First molecular characterization of a Turkish orf virus strain from a human based on a partial B2L sequence. Arch Virol 2013;158:1105-8.
3. Centers for Disease Control and Prevention (CDC). Human Orf Virus Infection from Household Exposures — United States, 2009– 2011. MMWR Morb Mortal Wkly Rep 2012;61:245-8.
4. McCabe D, Weston B, Storch G. Treatment of orf poxvirus lesion with cidofovir cream. Pediatr Infect Dis J 2003;22: 1027-8.
5. Lederman ER, Austin C, Trevino I, Reynolds MG, Swanson H, Cherry B, et al. ORF virus infection in children: Clinical characteristics, transmission, diagnostic methods, and future therapeutics. Pediatr Infect Dis J 2007;26:740-4.
6. Haig DM, McInnes CJ. Immunity and counter-immunity during infection with the parapoxvirus orf virus. Virus Res 2002;88:3-16.
7. Turan E, Yurt N, Erdemir AT, Gürel MS. Fasiyal Orf. Turk J Dermatol 2012; 6:58-60.
8. Simmons JF, Hafernick AC. Painless, red nodule on the finger of a veterinary student. Am Fam Physician 2012;86:77-8.

9. Gurel MS, Ozardali I, Bitiren M, San I, Zeren H. Giant orf on the nose. Eur J Dermatol 2002;12:183-5.
10. Duchateau NC, Aerts O, Lambert J. Autoinoculation with Orf virus (ecthyma contagiosum). Int J Dermatol 2014;53:e60-2.
11. Rieger H, Wetterkamp D, Kühn J, Langer M. Ecthyma contagiosum (Orf) as an uncommon differential diagnosis of infections of the hand. Unfallchirurg 2003;106:204-6.
12. Al-Qattan MM. Orf infection of the hand. J Hand Surg Am 2011;36:1855-8.
13. Bayindir Y, Bayraktar M, Karadag N, Ozcan H, Kayabas U, Otlu B, et al. Investigation and analysis of a human orf outbreak among people living on the same farm. New Microbiol 2011;34:37-43.
14. Midilli K, Erkiliç A, Kuşkucu M, Analay H, Erkiliç S, Benzonana N, et al. Nosocomial outbreak of disseminated orf infection in a burn unit, Gaziantep, Turkey, October to December 2012. Euro Surveill 2013;18:20425.