7 - 16 Yaş Çocuklarda Obezite Ve Allerjik Solunum Yolu Hastalığı İlişkisi

Öz

Giriş: Obezite ve astım prevelansı tüm dünyada birbirine paralel artış göstermektedir.Amaç: Obezite ve astım prevelansı tüm dünyada birbirine paralel artış göstermektedir. Bu çalışmada çocuklarda obezite ve allerjik solunum yolu hastalığı ilişkisini araştırmak amaçlanmıştır.Yöntemler: Yaşları 7-16 arasında 52' si obez, 87 olgu çalışmaya alınmıştır. Allerjik solunum yolu hastalığı öykü, fizik inceleme, anket, epidermal deri ve solunum fonksiyon testi ve ile değerlendirilmiştir. Astım tanısı tekrarlayan vizing atakları öyküsü, allerjik rinit tanısı uygun öykü ve epidermal deri testleri ile konulmuştur. Bulgular: Allerjik solunum yolu hastalığı %26,4 olguda belirlenmiştir. Bunların %57' si sadece allerjik rinit, %26' sı sadece astım ve % 17' si astım ve birlikte allerjik rinit tanısı almıştır. Obez ve obez olmayan kontrol olgular astım veya allerjik rinit tanısı açısından farklılık göstermemiştir (sırasıyla p=0.304 ve p=0.46). Atopik duyarlanma olguların %31' inde saptanmış ve obezlerde kontrollere göre anlamlı yüksek bulunmuştur (p=0.033). Sonuç: Obez çocuklarda atopik duyarlanma daha fazla görülmesine rağmen, astım ve allerjik rinit sıklığı obez olmayanlara göre farklı bulunmamıştır.

Anahtar Kelimeler

• Astım, atopi, obezite

THE RELATION BETWEEN OBESITY AND ALLERGIC AIRWAY DISEASES IN 7-16 YEARS OLD CHILDREN

Öz

Background:The prevelance of obesity and asthma have increased in parallel all around the world.Aim: We aimed to study the relationship between obesity and allergic airway diseases in children.Methods: 87 children seven to 16 years old, 52 of whom were obese, were included in the study. Allergic airway disease was evaluated by history, physical examination, questionnaire, skin prick and pulmonary function tests. Diagnosis of asthma or allergic rhinitis was made by history of recurrent wheezing episodes and history and skin prick tests, respectively.Results: Allergic airway disease was detected in 26,4% of cases. Among them allergic rhinitis, asthma and concomitant asthma and allergic rhinitis were found in 57%, 26% and 17% of cases, respectively. Obese and non-obese children did not differ considering asthma (p=0.304) and allergic rhinitis (p=0.46). Atopic sensitization was found in 31% of the cases. Obese children had significantly more frequent atopic sensitization than the control children (p=0.033).Conclusion: Although atopic sensitization was more common in obese children, the frequency of asthma and allergic rhinitis was not different in obese and non-obese children

Anahtar Kelimeler

• Asthma, atopy, obesity

Kaynakça

1. Troiano RP, Flegal KM. Overweight children and adolescents: description, epidemiology, and dermographics. Pediatrics
2. Schachter LM, Peat JK, Salome CM. Asthma and atopy in overweight 1998;101:497-504.
3. Cinaz P, Çamurdan MO, Maral I,Bideci A, Bakar C, Demirel F, Durukan E. 6-16 yaş arası 12.589 çocukta obesite sıklığı ve risk faktörleri. VIII. Ulusal Pediatrik Endokrinoloji Kongre Özet Kitabı, Erzurum 2003, S:230
4. Von Mutis E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax 2001;56: 835-838.
5. Kries von R, Hermann M, Grunert VP, von Mutius E: Is obesity a risk 3.The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 1998;351:1225-1232.
6. Gold DR, Damokosh AI, Dockery DW, Berkeycs. Body-mass index as a predictor of incident asthma in a prospective cohort of children. Pediatric Pulmonol 2003; 36: 514-521.
7. Saraçlar Y, Kuyucu S, Tuncer A, Şekerel B, Saçkesen C, Kocabaş C. 14. Chinn S, Rona RJ. Can the increase in body mass index explain the P r e va l e n c e o f a s t h m a t i c p h e n o t y p e s a n d b r o n ch i a l hyperresponsiveness in Turkish schoolchildren: an International Study of Asthma and Allergies in Childhood (ISAAC) phase 2 study. Ann Allergy Asthma Immunol 2003;91: 477-484.
8. To T, Vydykhan TN, Dell S, Tassoudji M, Harris JK. Is obesity associated with asthma in young children? J Pediatr 2004;144: 162- 168.

9. Çamurdan MO, Cinaz P, Bideci A, Demirel F, Bakar C, Bumin MA. 7- 16 yaş arası çocuklarda VKİ değerlerinin dağılımı. 8. Ulusal Pediatrik Endokrinoloji Kongresi 16-21 Aralık 2003 Erzurum Kongre Kitabı. S:135.
10. Figueroa-Munoz JI, Chinn S, Rona RJ. Association between obesity and asthma in 411 year old children in the UK. Thorax 2001;56: 133- 137.
11. Jarvis D, Chinn S, Potts J, Burney P: Association of body mass index with respiratory symptoms and atopy: results from the European Community respiratory Health Survey. Clin Exp allergy 2002;32: 831- 837.
12. Huang SL, Shiao GM, Chou P: Association between body mass index and allergy in teenage girls in Twain. Clin Exp Allergy 1999; 29: 323- 329.
13. Sangi H, Mueller WH. Which measure of body fat distribution is best for epidemiologic research among adolescents? Am J Epidemiol 1991;133:870-883.
14. Valdivia G, Shaheen S, Sterne J. Body mass index, asthma symptoms and IgE in young adults. Eur Respir J 1999;14(Suppl 30):142s.
15. Chinn S. Hughes JM, Rona RJ. Trends in growth and obesity in ethnic 9. Xu B, Jarvelin MR, Pekkanen J. Body build and atopy. J Allergy Clin groups in Britain. Arch Dis Child 1998;78: 513-517.