Acute Iron Poisoning in Children: An Ongoing Important Pediatric Emergency
Öz
Objective: Iron containing drugs are one of the most commonly prescribed drugs in our country and accidental or
suicidal poisoning continues to be an important pediatric emergency. Our aim was to evaluate the clinical, laboratory,
radiologic findings, and treatment approaches of children hospitalized with acute iron poisoning.
Material and Methods: The clinical, laboratory, and radiologic findings of and treatment approaches for 17 patients
aged 14 months-15 years hospitalized with acute iron poisoning were reviewed.
Results: The mean age was 37±35.2 months. Iron poisoning was accidental in 16 patients. The mean duration
between drug intake and hospital admission was 177±149 minutes. The mean ingested amount of iron was 35.4±19
mg/kg. The mean blood iron level was 232±136 mcg/dl. There was no significant relationship between the reported
dose of ingested iron and the blood iron level (p>0.05). There was no significant relationship between blood iron level
and ingestion time (p>0.05). Laboratory results revealed metabolic acidosis in 3 patients, respiratory acidosis in one
patient, leucocytosis in one patient, and prolonged activated partial thromboplastin time in one patient. The patients’
findings were not consistent with blood iron levels. Whole bowel irrigation and IV deferoxamine were used in 3 patients.
There was no death. The mean hospitalization duration was 2.8±1.1 days.
Conclusion: Accidental iron poisoning continues to be an important pediatric emergency. There are no correlations
between blood iron levels and the amount of ingested iron or the ingestion time. There was also no correlation between
the blood iron levels and the clinical, laboratory and radiographic findings in our study.
Anahtar Kelimeler
Kaynakça
- 1. Jayashree M, Singhi S. Changing trends and predictors of outcome in patients with acute poisoning admitted to the intensive care. J Trop Pediatr 2011;57:340-6.
- 2. Smolinske SC, Kaufman MM. Consumer perception of household hazardous materials. Clin Toxicol 2007;45:522-5.
- 3. Chang TP, Rangan C. Iron poisoning: A literature-based review of epidemiology, diagnosis, and management. Pediatr Emerg Care 2011;27:978-85.
- 4. Baranwal AK, Singhi SC. Acute iron poisoning: Management guidelines. Indian Pediatr. 2003;40:534-40.
- 5. Madiwale T, Liebelt E. Iron: Not a benign therapeutic drug. Curr Opin Pediatr 2006;18:174-9.
- 6. Skoczynska A, Kwiecinska D, Kielbinski M, Lukaszewski M. Acute iron poisoning in adult female. Hum Exp Toxicol 2007;26:663-6.
- 7. Porter JB. Concepts and goals in the management of transfusional iron overload. Am J Hematol 2007;82:1136-9.
- 8. Sipahi T, Karakurt C, Bakirtas A, Tavil B. Acute iron ingestion. Indian J Pediatr 2002;69:947-9.
Ayrıntılar
Birincil Dil
İngilizce
Konular
İç Hastalıkları
Bölüm
Araştırma Makalesi
Yazarlar
Yayımlanma Tarihi
30 Aralık 2018
Gönderilme Tarihi
18 Eylül 2017
Kabul Tarihi
7 Kasım 2017
Yayımlandığı Sayı
Yıl 2018 Cilt: 12 Sayı: 4