İnsan Parainfluenza Virüsü 'nün Çocuk Sağlığı Üzerindeki Etkileri: Bir Klinik Araştırma

Yıl 2024, ERKEN GÖRÜNÜMLÜ MAKALELER, 1 - 4

Furkan Kalaycı , Ece Karaköse , Ayça Çırak , Metin Yiğit

https://doi.org/10.12956/tchd.1487615

Öz

Amaç: Bu çalışma, İnsan Parainfluenza Virüsü (HPIV) enfeksiyonlarının çocuklarda klinik özelliklerini belirlemek, morbidite ve mortalite oranlarını değerlendirmek, ve kronik hastalıkların bu enfeksiyonların seyrine etkisini araştırmak amacıyla yapılmıştır.

Gereç ve Yöntemler: Araştırma, Ağustos 2019-Temmuz 2023 tarihleri arasında Ankara Bilkent Şehir Hastanesi Çocuk Hastanesi’ne başvuran, solunum yolu viral panelinde HPIV pozitifliği saptanan 0-18 yaş arası çocuklar üzerinde retrospektif ve kesitsel olarak yapılmıştır. Çoklu virüs pozitifliği gösteren hastalar çalışma dışında bırakılmıştır. İstatistiksel analizler SPSS 23.0 kullanılarak gerçekleştirilmiş ve p < 0.050 anlamlı kabul edilmiştir.

Bulgular: Çalışmaya 160 hasta dahil edildi ve bunların %61.2’si erkek, %38.8’i kadındı. En sık başvuru şikayetleri öksürük (%66.3) ve ateş (%52.5)’di. Hastaların %41.2’si yatırılarak tedavi edilmiş, %19.6’sı yoğun bakım ünitesinde
tedavi görmüştür. İnvaziv veya noninvaziv mekanik ventilasyon ihtiyacı %10 olarak gözlenmiştir. Akciğer infiltrasyonu ve kronik hastalık varlığının hipoksi ile istatistiksel olarak anlamlı ilişkisi bulunmuştur (p<0.001).

Sonuç: HPIV enfeksiyonları genellikle hafif seyirli olsa da, kronik hastalığı olan çocuklarda ciddi morbiditelere ve yoğun bakım ihtiyacına yol açabilmektedir. Bu bulgular, HPIV enfeksiyonu olan çocuklarda dikkatli klinik değerlendirme ve yakın takip gerekliliğini vurgulamaktadır. Çalışma, pediatrik yaş grubunda HPIV enfeksiyonlarının yönetimi ve tedavi stratejilerinin belirlenmesine katkı sağlayabilir.

Anahtar Kelimeler

Çocuk, Parainfluenza Virüs, Pnömoni, Üst Solunum Yolu Enfeksiyon

The Impact of Human Parainfluenza Virus on Child Health: A Clinical Study

Öz

Objective: This study aims to identify the clinical characteristics of Human Parainfluenza Virus (HPIV) infections in children, evaluate morbidity and mortality rates, and investigate the impact of chronic diseases on the course of these infections.

Material and Methods: The research was conducted retrospectively and cross-sectionally on children aged 0-18 who tested positive for HPIV in the respiratory viral panel at Ankara Bilkent City Hospital Children’s Hospital between August 2019 and July 2023. Patients with multiple virus positivity were excluded from the study.

Results: The study included 160 patients, of whom 61.2% were male and 38.8% were female. The most common presenting symptoms were cough (66.3%) and fever (52.5%). Of the patients, 41.2% were treated as inpatients, and 19.6% received care in the intensive care unit. The need for invasive or noninvasive mechanical ventilation was observed in 10% of the patients. There was a statistically significant association between the presence of lung infiltration and chronic disease with hypoxia (p < 0.001).

Conclusion: While HPIV infections are generally mild, they can lead to significant morbidity and the need for intensive care in children with chronic diseases. These findings highlight the necessity for careful clinical evaluation and close monitoring of children with HPIV infections. The study’s results may contribute to the management and treatment strategies for HPIV infections in the pediatric population.

Anahtar Kelimeler

Child, Parainfluenza Virus, Pneumonia, Upper Respiratory Tract Infection

Kaynakça

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