Öz
Dünyada en sık görülen genetik geçişli hastalıklardan biri olan beta talasemi, ülkemizde de önemli bir sağlık sorunu olmaya devam etmektedir. Ülkemizde beta talasemi taşıyıcılık oranı %2 civarındadır. Taşıyıcı olanların genellikle normal görünümde olmaları tarama programlarının gerekliliğini ortaya koymaktadır. Beta talaseminin sık görüldüğü yerlerden biri olan Muğla’da düzenli yapılan tarama programları sayesinde yeni hasta olguların sayısında da önemli derecede azalma olmuştur.
Anahtar Kelimeler
Beta talasemi majör Beta talasemi minör Hemoglobinopati Muğla
Kaynakça
- Cao A, Galanello R. Beta-thalassemia. Genet Med 2010;12:61-76.
- Guler E, Caliskan U, Albayrak C, Karacan M. Prevalence of beta- thalassemia and sickle cell anemia trait in premarital screening in Konya urban area, Turkey. J Pediatr Hematol Oncol 2007;29: 783-5.
- Bozkurt G. Thalassemia prevention and control program in the Turkish Republic of Northern Cyprus. In: Bozkurt G (ed). 2nd. International Thalassemia Summer School. KKTC:Girne, 2002: 41.
- Bozkurt G. Results from the North Cyprus thalassemia prevention program. Hemoglobin 2007;31:257-64.
- Amato A, Grisanti P, Lerone M, Ponzini D, Di Biagio P, Cappabianca MP, et al. Prevention strategies for severe hemoglobinopathies in endemic and nonendemic immigration countries: The Latium example. Prenat Diagn 2009;29:1171-4.
- Silvestroni E, Bianco I. Screening for microcytemia in Italy: Analysis of data collected in the past 30 years. Am J Hum Genet 1975;27:198-212.
- Çavdar AO, Arcasoy A. The incidence of beta-thalassemia and abnornal hemoglobins in Turkey. Acta Hematol 1971;45:313-8.
- Akar N, Çavdar AO, Dessi E, Loi A, Pirastu M,Cao A. Thalassemia mutations in Turkish populations. J Med Genet 1987;24:378-9
- Cao A, Pirastu M, Rosatelli MC. The prenatal diagnosis of thalassaemia. Br J Haematol 1986;63:215-20.
Öz
As one of the most common genetically inherited diseases in the world, beta thalassemia continues to be a major health problem in our country, too. In our country, the carrier rate is around 2%. The carriers’ appearance is usually normal and this reveals the necessity of screening programs. In Mugla, which is one of the places where thalassemia is frequently seen, occured a significant reduction in the number of cases, through regularly conducted screening programs
Anahtar Kelimeler
Beta thalassemia major Beta thalassemia minor Hemoglobinopathies Mugla
Kaynakça
- Cao A, Galanello R. Beta-thalassemia. Genet Med 2010;12:61-76.
- Guler E, Caliskan U, Albayrak C, Karacan M. Prevalence of beta- thalassemia and sickle cell anemia trait in premarital screening in Konya urban area, Turkey. J Pediatr Hematol Oncol 2007;29: 783-5.
- Bozkurt G. Thalassemia prevention and control program in the Turkish Republic of Northern Cyprus. In: Bozkurt G (ed). 2nd. International Thalassemia Summer School. KKTC:Girne, 2002: 41.
- Bozkurt G. Results from the North Cyprus thalassemia prevention program. Hemoglobin 2007;31:257-64.
- Amato A, Grisanti P, Lerone M, Ponzini D, Di Biagio P, Cappabianca MP, et al. Prevention strategies for severe hemoglobinopathies in endemic and nonendemic immigration countries: The Latium example. Prenat Diagn 2009;29:1171-4.
- Silvestroni E, Bianco I. Screening for microcytemia in Italy: Analysis of data collected in the past 30 years. Am J Hum Genet 1975;27:198-212.
- Çavdar AO, Arcasoy A. The incidence of beta-thalassemia and abnornal hemoglobins in Turkey. Acta Hematol 1971;45:313-8.
- Akar N, Çavdar AO, Dessi E, Loi A, Pirastu M,Cao A. Thalassemia mutations in Turkish populations. J Med Genet 1987;24:378-9
- Cao A, Pirastu M, Rosatelli MC. The prenatal diagnosis of thalassaemia. Br J Haematol 1986;63:215-20.
Ayrıntılar
| Diğer ID | JA38SY98NM |
|---|---|
| Bölüm | Derleme |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Ağustos 2015 |
| Gönderilme Tarihi | 1 Ağustos 2015 |
| Yayımlandığı Sayı | Yıl 2015 Cilt: 9 Sayı: 3 |