Case Report
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Organ Donation Following Brain Death Due to Increased Intracranial Pressure: An Adolescent Case Report

Year 2022, Volume: 16 Issue: 1, 75 - 78, 28.01.2022
https://doi.org/10.12956/tchd.885694

Abstract

Brain death is defined as the irreversible loss of all functions of the brain, the brainstem and cerebellum. Donors with irreversible brain damage and medically healthy organs other than the brain may be suitable organ donors. Despite the great progress on organ transplantation in recent years, the most important problem of organ transplantation is the insufficiency in organ donation. Therefore, it is very important to diagnose brain death in pediatric intensive care units to provide organ donors. Herein, we report a 17-year-old patient who had brain herniation due to increased intracranial pressure and was subsequently diagnosed with brain death. The patient’s organs including the lungs, both kidneys and both corneas were retrieved for donation.

References

  • Rangel-Castilla L, Gopinath S, Robertson CS. Management of intracranial hypertension [published correction appears in Neurol Clin 2008;26: xvii.
  • Türk Nöroloji Derneği Beyin Ölümü Tanı Klavuzu 2014; 20: 101-4.
  • Şantaş G, Şantaş F. Türkiye’de organ bağışının mevcut durumu ve organ bağışında stratejik iletişimin önemi. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 2018;9:163-8.
  • Gündüz RC, Sahin S, Uysal-Yazici M, Ayar G, Yakut HI, et al. Brain death and organ donation of children. The Turkish journal of pediatrics 2014;56:597-603.
  • Sagarin MJ, Chiang V, Sales JC, Barton ED, Wolfe RE, Vissers RMW, et al. Rapid sequence intubation for pediatric emergency airway management. Pediatr Emerg Care 2002;18:417‐23.
  • Gerardi MJ, Sacchetti AD, Cantor RM, Santamaria JP, Gauche M, Lucid W, et al. Rapid-sequence intubation of the pediatric patient. Pediatric Emergency Medicine Committee of the American College of Emergency Physicians. Ann Emerge Med 1996;28:55-74.
  • Yasa no. 2238 29 Mayıs 1979 Organ ve Doku Alınması, Saklanması, Aşılanması ve Nakli Hakkında Kanun. TC Resmi Gazete 3 June 1979; 16655: 1-4. Doku, Organ Nakli ve Diyaliz Hizmetleri Dairesi Başkanlığı, Türkiye Transplantasyon, Diyaliz İzlem Sistemleri, erişim 19.04.2020 https://organkds.saglik.gov.tr/dss/PUBLIC/Public Default2.aspx
  • Haberal M. Historical evolution of kidney and liver transplantation in Turkey. Transplant Proc1995;27:2771-4.
  • Türk Toraks Derneği, Ülkemizde Akciğer Nakli, erişim 19.04.2020, https://www.toraks.org.tr/halk/News.aspx? detail=3810 https://www.aa.com.tr/tr/saglik/turkiye-genelinde-gecen-yil-9-bin-477-organ-ve-doku-nakli-yapildi/1690942 erişim tarihi 18 ocak 2021.
  • Bayrakcı B, Çocuk Yoğun Bakım Ünitesinde Organ Donörünün Tıbbi Bakımı. Yoğun Bakım Dergisi 2004;4:186-9.
  • Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya, VN, et al. Management of the potential organ donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Crit Care Med 2015; 43: 1291–325.
  • Park J, Yang NR, Lee YJ, Hong KS. A Single-Center Experience with an Intensivist-Led Brain-Dead Donor Management Program. Ann Transplant 2018;23:828‐35
  • Friedman AL, Marquez E, Lewis JA. Organ Donation is an Indication for Renal Replacement Therapy (RRT). Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/organ-donation-is-an-indication-for-renal-replacement-therapy-rrt/. Accessed June 12, 2020.

Kafa İçi Basınç Artışı Sendromundan Beyin Ölümü ve Organ Donasyonuna Giden Bir Adölesan Olgu Sunumu

Year 2022, Volume: 16 Issue: 1, 75 - 78, 28.01.2022
https://doi.org/10.12956/tchd.885694

Abstract

Beyin, beyin sapı ve serebellum fonksiyonlarının geri dönüşümsüz kaybı beyin ölümü olarak tanımlanmaktadır. Geri dönüşümsüz beyin hasarı saptanan, tıbben beyin dışındaki organları sağlıklı olan donörler uygun organ donörü olabilirler. Son yıllarda organ naklindeki büyük gelişmelere rağmen, organ naklinin en önemli sorunu organ bağışındaki yetersizliktir. Bu nedenle organ donörü sağlanması açısından çocuk yoğun bakım ünitelerinde beyin ölümü tanısı koymak oldukça önemlidir. Burada 17 yaşında kafa içi basınç artışı sendromuna (KİBAS) bağlı beyin herniasyonu olan ve sonrasında beyin ölümü tanısı alan, böbrek, kornea ve akciğer nakli için donör olan bir olgu sunulmuştur.

References

  • Rangel-Castilla L, Gopinath S, Robertson CS. Management of intracranial hypertension [published correction appears in Neurol Clin 2008;26: xvii.
  • Türk Nöroloji Derneği Beyin Ölümü Tanı Klavuzu 2014; 20: 101-4.
  • Şantaş G, Şantaş F. Türkiye’de organ bağışının mevcut durumu ve organ bağışında stratejik iletişimin önemi. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 2018;9:163-8.
  • Gündüz RC, Sahin S, Uysal-Yazici M, Ayar G, Yakut HI, et al. Brain death and organ donation of children. The Turkish journal of pediatrics 2014;56:597-603.
  • Sagarin MJ, Chiang V, Sales JC, Barton ED, Wolfe RE, Vissers RMW, et al. Rapid sequence intubation for pediatric emergency airway management. Pediatr Emerg Care 2002;18:417‐23.
  • Gerardi MJ, Sacchetti AD, Cantor RM, Santamaria JP, Gauche M, Lucid W, et al. Rapid-sequence intubation of the pediatric patient. Pediatric Emergency Medicine Committee of the American College of Emergency Physicians. Ann Emerge Med 1996;28:55-74.
  • Yasa no. 2238 29 Mayıs 1979 Organ ve Doku Alınması, Saklanması, Aşılanması ve Nakli Hakkında Kanun. TC Resmi Gazete 3 June 1979; 16655: 1-4. Doku, Organ Nakli ve Diyaliz Hizmetleri Dairesi Başkanlığı, Türkiye Transplantasyon, Diyaliz İzlem Sistemleri, erişim 19.04.2020 https://organkds.saglik.gov.tr/dss/PUBLIC/Public Default2.aspx
  • Haberal M. Historical evolution of kidney and liver transplantation in Turkey. Transplant Proc1995;27:2771-4.
  • Türk Toraks Derneği, Ülkemizde Akciğer Nakli, erişim 19.04.2020, https://www.toraks.org.tr/halk/News.aspx? detail=3810 https://www.aa.com.tr/tr/saglik/turkiye-genelinde-gecen-yil-9-bin-477-organ-ve-doku-nakli-yapildi/1690942 erişim tarihi 18 ocak 2021.
  • Bayrakcı B, Çocuk Yoğun Bakım Ünitesinde Organ Donörünün Tıbbi Bakımı. Yoğun Bakım Dergisi 2004;4:186-9.
  • Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya, VN, et al. Management of the potential organ donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Crit Care Med 2015; 43: 1291–325.
  • Park J, Yang NR, Lee YJ, Hong KS. A Single-Center Experience with an Intensivist-Led Brain-Dead Donor Management Program. Ann Transplant 2018;23:828‐35
  • Friedman AL, Marquez E, Lewis JA. Organ Donation is an Indication for Renal Replacement Therapy (RRT). Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/organ-donation-is-an-indication-for-renal-replacement-therapy-rrt/. Accessed June 12, 2020.
There are 13 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section CASE REPORTS
Authors

Emine Gulsah Torun 0000-0003-2005-7082

Mutlu Uysal Yazıcı 0000-0001-7377-4718

Ebru Azapağası 0000-0002-0684-8219

Fatih Mehmet Akif Özdemir 0000-0003-4820-1234

Nesrin Ceylan 0000-0001-5844-1261

Publication Date January 28, 2022
Submission Date February 25, 2021
Published in Issue Year 2022 Volume: 16 Issue: 1

Cite

Vancouver Torun EG, Uysal Yazıcı M, Azapağası E, Özdemir FMA, Ceylan N. Kafa İçi Basınç Artışı Sendromundan Beyin Ölümü ve Organ Donasyonuna Giden Bir Adölesan Olgu Sunumu. Turkish J Pediatr Dis. 2022;16(1):75-8.


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