Synthesis, Characterization and Investigation of Some Photophysical Properties of Novel Benzothiazole Based Pyridine Derivative

Öz

Benzothiazole and its derivates have been play important role in chemical, biological and pharmacological reactions due to its heterocyclic structure. In this study, fluorescent active novel benzothiazole substitute picolinoyl chloride derivate 6-((2-(benzothiazol-2 yl)phenyl)carbamoyl)picolinoyl chloride (BTPCP) successfully synthesized and characterized. Its structure was identified by classic spectroscopic methods (FT-IR, 1H-NMR and 13C-NMR). Its photophysical properties was investigated by using UV-Vis Spectrophotometer and Fluorescence Spectrophotometer. Benzothiazole substitute picolinoyl chloride derivate (BTPCP) has been shown fluorescence activity The novel fluorescence active BTPCP is expected to find application in especially sensor, different biological and pharmacological studies.

Anahtar Kelimeler

• Benzothiazole
• picolinoyl chloride
• fluorescence
• organic synthesis
• spectroscopic analysis

Synthesis, Characterization and Investigation of Some Photophysical Properties of Novel Benzothiazole Based Pyridine Derivative

Öz

Benzotiyazol ve türevleri, heterosiklik yapıları nedeniyle kimyasal, biyolojik ve farmakolojik reaksiyonlarda önemli rol oynamaktadır. Bu çalışmada, floresan aktif yeni benzotiyazol substitue pikolinoil klorür türevi 6-((2-(benzotiyazol-2il)fenil)karbamoil)pikolinoil klorür (BTPCP) başarıyla sentezlenmiş ve karakterize edilmiştir. Sentezlenen BTPCP’nin molekül yapısı klasik spektroskopik yöntemler (FT-IR, 1H-NMR ve 13C-NMR) kullanılarak belirlenmiştir. BTPCP’nin fotofiziksel özellikleri Uv-Vıs Spektrofotometresi ve Flouresence Spektrofotometresi kullanılarak incelenmiştir. Yapılan incelemeler sonucunda benzotiyazol substitue pikolinoil klorür türevi BTPCP floresans aktivitesi gösterdiği belirlenmiştir. Yeni floresans aktif BTPCP'nin sensör çalışmaları başta olmak üzere, farklı biyolojik ve farmakolojik çalışmalarda uygulama bulması beklenmektedir.

Anahtar Kelimeler

• Benzotiyazol
• Floresans Pikolinoil Klorür Türevi
• Organik Sentez
• Spektroskopik Analiz

Kaynakça

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